Long Term Clinical Outcomes of Hydrophilic and Hydrophobic Versions of a Trifocal IOL with the Same Optical Design

Abstract

Purpose To show the visual and refractive outcomes in Asian eyes with cataract when bilaterally implanted with either a hydrophobic FineVision POD F GF or a hydrophilic FineVision POD F intraocular lens (IOL). Methods Forty-six patients were randomized to receive POD F GF or POD F IOLs. Visual and refractive outcomes were assessed up to 24 months post-surgery. Measurements included uncorrected-distance visual acuity, corrected-distance visual acuity (CDVA), distance-corrected intermediate visual acuity (DCIVA), distance-corrected near visual acuity (DCNVA), refraction, defocus curve, photopic and mesopic contrast sensitivity, and patient-reported outcomes. Results Mean spherical equivalent was close to emmetropia for both groups and stable across postoperative visits. Overall, 97.73% and 100% of eyes in the POD F GF IOL group and 95.65% and 100%, of eyes in the POD F IOL group were within ±1.00D of the target refraction at 12 and 24 months, respectively. All patients showed a CDVA of ≥20/25 at 12- and 24-months post-surgery. In both groups, 24 months post-surgery 91% of patients presented a DCIVA of ≥20/25 and 83.3% of patients had a DCNVA of ≥20/25. Defocus curve showed continuous visual acuity, being 20/32 or better in both groups over a 4.00D range between 1.00D and −3.00/-3.50D. Both groups showed good contrast sensitivity values for photopic and mesopic conditions. Overall, 86.4%, 86.4%, and 72.7% of patients implanted with the POD F GF IOL reported not wearing glasses at all for distance, intermediate, and near vision, respectively. These values were 81.8%, 86.4%, and 90.9% for patients implanted with the POD F IOL. Both groups of patients reported similar satisfaction percentages (100% very satisfied/satisfied) and would recommend the procedure (100% definitively yes/probably yes). Conclusion This study demonstrates good visual and refractive outcomes for both the FineVision POD F GF and the FineVision POD F IOLs when implanted in Asian eyes.

Analysis of the Visual Function With the Continuous Transitional Focus Intraocular Lens Precizon Presbyopic

“…The analysis of the binocular defocus curve revealed an extended range of functional vision was provided with the refractive multi-segmented IOL evaluated, as in previous studies analysing the same IOL [7,8]. Speci cally, mean binocular distance-corrected visual acuity was over 0.20 logMAR for defocus levels from + 1.50 to -3.00 D. Alió and colleagues [7] reported in their series evaluating the Precizon Presbyopic IOL that it was able to provide a visual acuity of 0.16 logMAR or better for defocus levels between + 1.00 and − 2.50 D. All these visual outcomes were consistent with those provided by other modalities of presbyopia-correcting IOLs, such as hybrid IOLs combining an extended depth of focus (EDOF) and a diffractive multifocal pro le [13,14] or conventional trifocal diffractive IOLs [15][16][17]. Shin et al [13] reported that the distance-corrected visual acuity in the binocular defocus curve of 35 patients implanted with the Tecnis Synergy™ IOL was 0.11 logMAR or better for the range of defocus levels between + 0.50 and − 2.50 D. Burkhard Dick et al [15] found in a sample of 95 eyes implanted with the Tecnis Synergy IOL and in a sample of 52 eyes implanted with the diffractive trifocal IOL PanOptix that mean corrected-distance visual acuities at the 3-month binocular defocus curve were 0.10 logMAR or better for the defocus levels between + 0.50 and − 3.00 D. The good level of visual rehabilitation achieved with the evaluated IOL agreed with the high level of spectacle independence found (90%).…”

Long-term trifocal toric intraocular lens outcomes in Asian eyes after cataract surgery

“…For the sample size calculation, the following parameters were used: continuous outcome, noninferiority trial, an α of 0.05; a power of 0.95; 2-sided test; an expected SD of outcome of 0.07 logMAR (based on clinical outcomes obtained by the same investigator on the spherical model of this IOL); and a noninferiority limit of 0.04 logMAR. 17 Using the Sealed Envelope Power calculator and to show noninferiority between the study group and the control cohort on monocular CDVA (first implanted eyes only), 80 eyes/patients were needed. 18 With an expected drop-out rate of 15%, a minimum number of 95 patients had to be recruited.…”

Prospects for the Use of Monofocal IOLs with Extended Depth of Focus (EDOF) Instead of Traditional Multifocal (Trifocal) IOLs in Cataract Surgery

“…ИОЛ выполнена из гидрофобного мягкого акрила с УФ-фильтром, число Аббе -55, имеет заднюю ахроматическую дифракционную поверхность для усиления восприятия контрастности и эшелетт дизайн, который позволяет продлевать диапазон фокуса света [10][11][12]. В качестве сравнительных оценивались, в большинстве случаев, традиционные ТФИОЛ («PanOptix», «FineVison» и «Lisa tri 839MP») [13][14][15]. Во всех исследованиях, включенных в данный обзор, была выполнена двусторонняя имплантация.…”