Long-term complications after phacoemulsification for cataract removal in dogs: 172 cases (1995–2002)

Sigle, Kelly J.; Nasisse, M P

doi:10.2460/javma.228.1.74

Cited by 117 publications

(204 citation statements)

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“…With these results of humidity kept in mind, it can explain why corneal sensitivity values (filament length) obtained in the present study are lower than those obtained in previous studies (Barrett et al, 1991;Good et al, 2003;Dorbandt et al, 2017). Although some previous studies in humans and dogs demonstrated the analgesic action of flurbiprofen and ketorolac (Sigle and Nasisse, 2006;Maca et al, 2010), the present study suggests that the ophthalmic application of these two drugs do not promote analgesic activity on corneal nociceptor activity in healthy canine eyes. Another recent study (Dorbandt et al, 2017) also demonstrated a lack of analgesic activity after topical application of flurbiprofen to canine eyes.…”

Section: Introductioncontrasting

confidence: 56%

“…Topical NSAIDS are primarily used for inflammatory ocular conditions such as the suppression of uveitis that may be present before and after intraocular surgery http://www.openveterinaryjournal.com R. Cantarella et al Open Veterinary Journal, (2017), Vol. 7(3): 254-260 ________________________________________________________________________________________________________ 255 (Giuliano, 2004;Sigle and Nasisse, 2006;Kim et al, 2010;Maca et al, 2010;Klein et al, 2011). Chen et al (1997) showed that the application of topical NSAID ophthalmic solutions effectively reduced corneal sensitivity as well as the sensitivity of polymodal nociceptors.…”

Section: Introductionmentioning

confidence: 99%

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Effects of topical flurbiprofen sodium, diclofenac sodium, ketorolac tromethamine and benzalkonium chloride on corneal sensitivity in normal dogs

Cantarella¹,

Oliveira²,

Dorbandt³

et al. 2017

Open Vet J.

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To evaluate corneal sensitivity by using the Cochet-Bonnet® esthesiometer in normal canine eyes at different time points following instillation of three different topical non-steroidal anti-inflammatory drugs (flurbiprofen sodium 0.03%, diclofenac sodium 0.1% and ketorolac tromethamine 0.5%) and benzalkonium chloride 0.01%. Six healthy mixed breed dogs from the same litter were used in two different stages. First, one drop of flurbiprofen sodium 0.03% and diclofenac sodium 0.1% in each eye; second, one drop of ketorolac tromethamine 0.5% and benzalkonium chloride 0.01% in each eye. Baseline esthesiometry was obtained before eye drop application and every 15 minutes thereafter until a total of 105 minutes of evaluation time. A one-week interval was allowed between the two treatment phases. Statistical analysis was used to compare means according to time of evaluation and drug used. Diclofenac sodium 0.1% decreased corneal sensitivity at 75 and 90 minutes (P > 0.015) with possible interference on neuronal nociceptive activity and analgesic effect while ketorolac tromethamine 0.5% did not show any variation for esthesiometry means along the evaluation. Flurbiprofen sodium 0.03% resulted in increased esthesiometry values 30 minutes after instillation (P > 0.013), increasing corneal sensitivity and possibly producing a greater irritant corneal effect over its analgesic properties. Benzalkonium chloride 0.01% significantly increased corneal sensitivity at 15 minutes of evaluation (P > 0.001), most likely resulting from its irritating effect. Esthesiometry did not allow a definite conclusion over the analgesic effect of the NSAIDs tested; however it was effective in detecting fluctuations in corneal sensitivity.

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Section: Introductioncontrasting

confidence: 56%

Section: Introductionmentioning

confidence: 99%

Effects of topical flurbiprofen sodium, diclofenac sodium, ketorolac tromethamine and benzalkonium chloride on corneal sensitivity in normal dogs

Cantarella¹,

Oliveira²,

Dorbandt³

et al. 2017

Open Vet J.

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“…Phacoemulsification normally reduces surgical trauma where access to the lens is gained through a small incision on the ocular surface (Pereira et al 1999, Özgen-cil 2005, Sigle & Nasisse 2006. Moreover, it allows the most efficient removal of the lens material, minimizing endothelial damage (Özgencil 2005, Sigle & Nasisse 2006.…”

Section: Introductionmentioning

confidence: 99%

A and B mode ultrasonography in preoperative evaluation of lens and posterior segment of dogs eyes with cataract

et al. 2010

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RESUMO.-[Ultrassonografia em modo A e B na avaliação pré-operatória da lente e do segmento posterior de olhos de cães com catarata.] A ultrassonografia do segmento posterior do bulbo do olho é etapa indispensá-vel na avaliação de cães com catarata que serão submetidos à facectomia, uma vez que a oftalmoscopia não é factível quando há opacificação da lente, notadamente nas cataratas maduras. Este estudo avaliou as condições ecográficas da lente cataratogênica e do fundo de olho de cães cursando com catarata. Foram avaliados 30 cães (56 olhos), sendo 10 machos e 20 fêmeas, cursando com catarata em diferentes estágios de desenvolvimento. Realizou-se a ecografia em modo A e B simultaneamente. Os exames revelaram catarata cortical anterior, posterior e nuclear em 12 olhos (21,4%), catarata cortical anterior, posterior, nuclear e capsular posterior em 23 olhos (41%), catarata cortical anterior, posterior e capsular posterior em um olho (1,7%), catarata cortical anterior e nuclear Ultrasonography of the lens and posterior segment is an indispensable step in the preoperative evaluation of dogs with cataracts, since ophthalmoscopy is not feasible when there is opacification of the lens. This study evaluated the echographic conditions of cataractous lens and fundus of the eye in dogs affected by cataracts. The study was conducted in 30 dogs (56 eyes), 10 males and 20 females, with different types of cataracts at different stages of development. Echography in A and B modes, simultaneously, was carried out for the examination of the lens and posterior segment. The examinations revealed anterior cortical, posterior cortical and nuclear cataract in 12 eyes (21.4%), anterior cortical, posterior cortical, nuclear and posterior capsular in 23 eyes (41%), anterior cortical, posterior cortical and posterior capsular cataract in one eye (1.7%), anterior cortical and nuclear cataract in one eye (1.7%), anterior cortical, nuclear and posterior capsular cataract in five eyes (8.9%), and anterior cortical cataract in seven eyes (12.5%). Abnormal ultrasonographic alterations were observed in the posterior segment in 26 eyes evaluated (46.4%). Vitreal degeneration was detected in 12 eyes (21.4%), images of vitreal exudate or hemorrhage in seven eyes (12.5%), persistence of hyaloid artery in four eyes (7.1%) and lens subluxation in three eyes (5.3%). The results obtained reiterate the importance of ultrasonography in canine patients presented for cataract surgery given that alterations of the posterior segment are difficult to identify in a clinical examination when the lens is opacified. em um olho (1,7%), catarata cortical anterior, nuclear e capsular posterior em cinco olhos (8,9%) e catarata cortical anterior em sete olhos (12,5%). Alterações no segmento posterior foram observadas, à ultrassonografia, em 26 olhos avaliados (46,4%). Degeneração vítrea foi detectada em 12 olhos (21,4%), imagens compatíveis com exsudato ou hemorragia em sete olhos (12,5%), persistência da artéria hialóide em quatro olhos (7,1%) e subluxação da lente em t...

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“…In the last decade, phacoemulsification has been becoming a common surgical procedure for restoring vision in veterinary patients with cataract [9,12,19]. Postoperative pain can be caused by intraocular manipulations that irritate intraocular tissue and induce the subsequent inflammatory response in the veterinary patient undergoing ocular surgery including phacoemulsification [13].…”

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confidence: 99%

Effect of Topical Administration of 0.8% Nalbuphine on the Cornea in Dogs after Phacoemulsification

Lee

Lin

Chi

et al. 2013

The Journal of Veterinary Medical Science

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ABSTRACT. It is suggested that topical application of opioids may provide localized analgesia without delay in corneal wound healing. This study was designed to evaluate the effect of topical application of 0.8% nalbuphine on post-operative ocular pain in dogs. Twelve eyes from 11 dogs undergoing phacoemulsification cataract surgery were divided into a nalbuphine group (n=6) and saline group (n=6). Postoperatively, the nalbuphine group received 0.1 ml of topical 0.8% alkalinized nalbuphine (pH 5.6) every 8 hr, and the saline group received 0.1 ml of topical saline (pH 5.9) as a placebo. All dogs received systemic postoperative pain managements with oral tramadol (4 mg/kg) and prednisolone (0.5 mg/kg) every 8 hr. All dogs received pre-and post-ophthalmic examinations. Pain was scored in the dogs using a pain scoring system modified from the University of Melbourne pain scale at 15, 30 and 60 min following the topical treatment on days 1 and 2 (24 and 48 hr after surgery). Eye blink frequency and corneal touch threshold (CTT) were recorded at the same time. There was no statistical difference in the pain score between groups. Significant decreases in CTT, blepharospasm and eye blink frequency were observed after the topical nalbuphine treatment. This indicated that topical application of 0.8% nalbuphine solution can produce a rapid reduction of corneal discomfort in dogs.

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Long-term complications after phacoemulsification for cataract removal in dogs: 172 cases (1995–2002)

Abstract: Evaluation of breed and cataract hypermaturity may aid in the selection of patients. The increasing prevalence of postoperative complications with time indicated that longterm monitoring is warranted.

Cited by 117 publications

References 30 publications

Effects of topical flurbiprofen sodium, diclofenac sodium, ketorolac tromethamine and benzalkonium chloride on corneal sensitivity in normal dogs

Effects of topical flurbiprofen sodium, diclofenac sodium, ketorolac tromethamine and benzalkonium chloride on corneal sensitivity in normal dogs

A and B mode ultrasonography in preoperative evaluation of lens and posterior segment of dogs eyes with cataract

Effect of Topical Administration of 0.8% Nalbuphine on the Cornea in Dogs after Phacoemulsification

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