Long-term complications of critical care

Desai, Sanjay V.; Law, Tyler J.; Needham, Dale M.

doi:10.1097/ccm.0b013e3181fd66e5

Cited by 718 publications

(616 citation statements)

References 140 publications

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“…8 • Clinically significant signs and symptoms of posttraumatic stress disorder occur in 28% of ICU survivors. 2,9 These signs and symptoms may not improve and have been reported in patients studied 8 years after ICU discharge. 2 …”

Section: Psychological Impairmentsmentioning

confidence: 90%

“…2,9 These signs and symptoms may not improve and have been reported in patients studied 8 years after ICU discharge. 2 …”

Section: Psychological Impairmentsmentioning

confidence: 90%

“…2,5,6 Cognitive function improves in some patients during the first year after discharge, but patients may not return to their pre-ICU level of cognitive functioning. 2,5,6 • 75% of ICU survivors with acute respiratory distress syndrome experience neurocognitive impairment at hospital discharge. These impairments are still present 1 year later in 46% and 6 years later in 25%.…”

Section: Mortality Ratesmentioning

confidence: 99%

“…7 • In ICU survivors more than 65 years old who had severe sepsis, post-ICU cognitive impairment lasts up to 8 years. 2 …”

Section: Mortality Ratesmentioning

confidence: 99%

“…11 • 50% of ICU survivors require caregiver assistance 1 year after ICU discharge. 2,12,13 The support required may range from assistance with activities of daily living to full care.…”

Section: Return To Previous Statusmentioning

confidence: 99%

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Long-Term Consequences of Critical Illness: A New Opportunity For High-Impact Critical Care Nurses

Harvey

Davidson

2011

Critical Care Nurse

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Section: Psychological Impairmentsmentioning

confidence: 90%

“…2,9 These signs and symptoms may not improve and have been reported in patients studied 8 years after ICU discharge. 2 …”

Section: Psychological Impairmentsmentioning

confidence: 90%

Section: Mortality Ratesmentioning

confidence: 99%

“…7 • In ICU survivors more than 65 years old who had severe sepsis, post-ICU cognitive impairment lasts up to 8 years. 2 …”

Section: Mortality Ratesmentioning

confidence: 99%

“…11 • 50% of ICU survivors require caregiver assistance 1 year after ICU discharge. 2,12,13 The support required may range from assistance with activities of daily living to full care.…”

Section: Return To Previous Statusmentioning

confidence: 99%

See 3 more Smart Citations

Long-Term Consequences of Critical Illness: A New Opportunity For High-Impact Critical Care Nurses

Harvey

Davidson

2011

Critical Care Nurse

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Clinical Outcomes Among Patients With 1-Year Survival Following Intensive Care Unit Treatment for COVID-19

Heesakkers¹,

Hoeven²,

Corsten

et al. 2022

JAMA

200

158

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IMPORTANCE One-year outcomes in patients who have had COVID-19 and who received treatment in the intensive care unit (ICU) are unknown.OBJECTIVE To assess the occurrence of physical, mental, and cognitive symptoms among patients with COVID-19 at 1 year after ICU treatment. DESIGN, SETTING, AND PARTICIPANTS An exploratory prospective multicenter cohort study conducted in ICUs of 11 Dutch hospitals. Patients (N = 452) with COVID-19, aged 16 years and older, and alive after hospital discharge following admission to 1 of the 11 ICUs during the first COVID-19 surge (March 1, 2020, until July 1, 2020) were eligible for inclusion. Patients were followed up for 1 year, and the date of final follow-up was June 16, 2021. EXPOSURES Patients with COVID-19 who received ICU treatment and survived 1 year after ICU admission. MAIN OUTCOMES AND MEASURES The main outcomes were self-reported occurrence of physical symptoms (frailty [Clinical Frailty Scale score Ն5], fatigue [Checklist Individual Strength-fatigue subscale score Ն27], physical problems), mental symptoms (anxiety [Hospital Anxiety and Depression {HADS} subscale score Ն8], depression [HADS subscale score Ն8], posttraumatic stress disorder [mean Impact of Event Scale score Ն1.75]), and cognitive symptoms (Cognitive Failure Questionnaire-14 score Ն43) 1 year after ICU treatment and measured with validated questionnaires. RESULTS Of the 452 eligible patients, 301 (66.8%) patients could be included, and 246 (81.5%) patients (mean [SD] age, 61.2 [9.3] years; 176 men [71.5%]; median ICU stay, 18 days [IQR, 11 to 32]) completed the 1-year follow-up questionnaires. At 1 year after ICU treatment for COVID-19, physical symptoms were reported by 182 of 245 patients (74.3% [95% CI, 68.3% to 79.6%]), mental symptoms were reported by 64 of 244 patients (26.2% [95% CI, 20.8% to 32.2%]), and cognitive symptoms were reported by 39 of 241 patients (16.2% [95% CI, 11.8% to 21.5%]). The most frequently reported new physical problems were weakened condition (95/244 patients [38.9%]), joint stiffness (64/243 patients [26.3%]) joint pain (62/243 patients [25.5%]), muscle weakness (60/242 patients [24.8%]) and myalgia (52/244 patients [21.3%]). CONCLUSIONS AND RELEVANCEIn this exploratory study of patients in 11 Dutch hospitals who survived 1 year following ICU treatment for COVID-19, physical, mental, or cognitive symptoms were frequently reported.

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Analysis of Anxiety or Depression and Long-term Mortality Among Survivors of Out-of-Hospital Cardiac Arrest

Lee

Cho

et al. 2023

JAMA Netw Open

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ImportanceThe recent American Heart Association guidelines added a sixth link in the chain of survival highlighting recovery and emphasized the importance of psychiatric outcome and recovery for survivors of out-of-hospital cardiac arrest (OHCA). The prevalence of psychiatric disorders among this population was higher than that in the general population.ObjectiveTo examine the prevalence of depression or anxiety and the association of these conditions with long-term mortality among individuals who survive OHCA.Design, Setting, and ParticipantsA longitudinal population-based cohort study was conducted to analyze long-term prognosis in patients hospitalized for OHCA between January 1, 2005, and December 31, 2015, who survived for 1 year or longer. Patients with cardiac arrest due to traumatic or nonmedical causes, such as injuries, poisoning, asphyxiation, burns, or anaphylaxis, were excluded. Data were extracted on depression or anxiety diagnoses in this population within 1 year from the database of the Korean National Health Insurance Service and analyzed April 7, 2022, and reanalyzed January 19 to 20, 2023.Main Outcomes and MeasuresFollow-up data were obtained for up to 14 years, and the primary outcome was long-term cumulative mortality. Long-term mortality among patients with and without a diagnosis of depression or anxiety were evaluated.ResultsThe analysis included 2373 patients; 1860 (78.4%) were male, and the median age was 53.0 (IQR, 44.0-62.0) years . A total of 397 (16.7%) patients were diagnosed with depression or anxiety, 251 (10.6%) were diagnosed with depression, and 227 (9.6%) were diagnosed with anxiety. The incidence of long-term mortality was significantly higher in the group diagnosed with depression or anxiety than in the group without depression or anxiety (141 of 397 [35.5%] vs 534 of 1976 [27.0%]; P = .001). With multivariate Cox proportional hazards regression analysis, the adjusted hazard ratio of long-term mortality for total patients with depression or anxiety was 1.41 (95% CI, 1.17-1.70); depression, 1.44 (95% CI, 1.16-1.79); and anxiety, 1.20 (95% CI, 0.94-1.53).Conclusions and RelevanceIn this study, among the patients who experienced OHCA, those diagnosed with depression or anxiety had higher long-term mortality rates than those without depression or anxiety. These findings suggest that psychological and neurologic rehabilitation intervention for survivors of OHCA may be needed to improve long-term survival.

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Long-term complications of critical care

Cited by 718 publications

References 140 publications

Long-Term Consequences of Critical Illness: A New Opportunity For High-Impact Critical Care Nurses

Long-Term Consequences of Critical Illness: A New Opportunity For High-Impact Critical Care Nurses

Clinical Outcomes Among Patients With 1-Year Survival Following Intensive Care Unit Treatment for COVID-19

Analysis of Anxiety or Depression and Long-term Mortality Among Survivors of Out-of-Hospital Cardiac Arrest

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