Managing Negative Symptoms of Schizophrenia 2020
DOI: 10.1093/med/9780198840121.003.0003
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Long-term course of negative symptoms in schizophrenia

Abstract: The chapter focuses on the relationship of negative and positive symptoms in schizophrenia. Negative symptoms should be evaluated in a relation to positive symptoms both cross-sectionally and long term (prospectively/retrospectively). Two types of long-term interaction between negative and positive symptoms could be distinguished: (1) relatively synchronized, and (2) relatively desynchronized. Synchronization of negative and positive symptoms is characterized by their unidirectional long-term course. Desynchro… Show more

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“…The following symptoms were collected by Raspopova from Kazakhstan: "emotional decline, socially withdrawn and passive, gross personality changes, narrowing of the range of interests, increasing autism, slowly increasing autism, slight decrease in energy potential, violation of logical harmony and of the purposefulness of thinking; disorganization of psychic activity; a significant decrease in interests and activity characteristic for a given person; emotional impoverishment; increasing social withdrawal (autism); various disorders of The most noticeable difference in the current descriptions of negative symptoms in the English language literature is the inclusion of "personality changes ("personality shift")" in the negative symptom domain in some countries (e.g., Russia, Ukraine, and Kazakhstan) and the proposed analysis of the long-term course and relationship of negative symptoms to positive and other symptom domains during the course of schizophrenia (16,18).…”
Section: Discussionmentioning
confidence: 99%
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“…The following symptoms were collected by Raspopova from Kazakhstan: "emotional decline, socially withdrawn and passive, gross personality changes, narrowing of the range of interests, increasing autism, slowly increasing autism, slight decrease in energy potential, violation of logical harmony and of the purposefulness of thinking; disorganization of psychic activity; a significant decrease in interests and activity characteristic for a given person; emotional impoverishment; increasing social withdrawal (autism); various disorders of The most noticeable difference in the current descriptions of negative symptoms in the English language literature is the inclusion of "personality changes ("personality shift")" in the negative symptom domain in some countries (e.g., Russia, Ukraine, and Kazakhstan) and the proposed analysis of the long-term course and relationship of negative symptoms to positive and other symptom domains during the course of schizophrenia (16,18).…”
Section: Discussionmentioning
confidence: 99%
“…The Russian school also emphasizes the "long-term course of negative symptoms and their relationship" between symptom domains in the course of schizophrenia; for example, it differentiates between a "synchronized" and "desynchronized" course of positive and negative symptoms (18). In the case of a "synchronized" relationship between positive and negative symptoms, the secondary nature of the increase in severity of negative symptoms can be hypothesized, while in the case of a "desynchronized" course, the increase in the severity of negative symptoms is not associated with an increase in positive symptoms.…”
Section: Discussion Evaluationmentioning
confidence: 99%
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