Long term effect of air pollution on incident hospital admissions: Results from the Italian Longitudinal Study within LIFE MED HISS project

Gandini, Martina; Scarinzi, Cecilia; Bande, Stefano; Berti, Giovanna; Carnà, Paolo; Ciancarella, Luisella; Costa, Giuseppe; Demaria, Moreno; Ghigo, Stefania; Piersanti, Antonio; Rowinski, Maria; Spadea, Teresa; Stroscia, Morena; Cadum, Ennio

doi:10.1016/j.envint.2018.10.020

Cited by 70 publications

(30 citation statements)

References 32 publications

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“…After assessing 58 full‐text for eligibility; we excluded nine studies because of: (1) no PM 2.5 data for the hypertension outcome ( n = 3), (2) increments for the pollutant concentration was change from previous concentration/place ( n = 2), (3) no clear data on hazard ratio, only in a diagram without precise data on hazard ratio and confidence interval ( n = 1), and (4) no specific data on pollutants, only distance from highways/road ( n = 3) (Figure 1). We included 49 articles in qualitative and quantitative synthesis; 5 articles were a joint cohort studies comprising of 2 (Dehbi 2017), 2 (Stockfelt 2018), 3 (Cai 2018), 11 (ESCAPE 2014), and 22 (Beelen 2014) cohorts, adding up to a total of 84 cohorts 1,3,5‐7,9‐52 . There were a total of 28 215 394 subjects from 84 cohorts.…”

Section: Resultsmentioning

confidence: 99%

A time‐to‐event analysis on air pollutants with the risk of cardiovascular disease and mortality: A systematic review and meta‐analysis of 84 cohort studies

Pranata

Vania

Tondas

et al. 2020

J Evidence Based Medicine

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Section: Resultsmentioning

confidence: 99%

A time‐to‐event analysis on air pollutants with the risk of cardiovascular disease and mortality: A systematic review and meta‐analysis of 84 cohort studies

Pranata

Vania

Tondas

et al. 2020

J Evidence Based Medicine

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“…Before that, the ambient air pollution in China had dramatically worsened due to the rapid increase in industrialization, automobile use, and energy consumption since 2000 [31]. The average concentration of PM 2.5 in our study was much higher than those in some western countries [31,32,33]. Hence, the relationship between high PM 2.5 level and outpatient and emergency room visits might not be detected in high concentrations of ambient PM 2.5 .…”

Section: Discussionmentioning

confidence: 70%

Fine Particulate Air Pollution and Hospital Utilization for Upper Respiratory Tract Infections in Beijing, China

Zhang

Tian

Zhang

et al. 2019

IJERPH

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Few studies have examined the association between fine particulate matter (PM2.5) and upper respiratory tract infections (URTI) in urban cities. The principal aim of the present study was to evaluate the short-term impact of PM2.5 on the incidence of URTI in Beijing, China. Data on hospital visits due to URTI from 1 October 2010 to 30 September 2012 were obtained from the Beijing Medical Claim Data for Employees, a health insurance database. Daily PM2.5 concentration was acquired from the embassy of the United States of America (US) located in Beijing. A generalized additive Poisson model was used to analyze the effect of PM2.5 on hospital visits for URTI. We found that a 10 μg/m3 increase in PM2.5 concentration was associated with 0.84% (95% CI, 0.05–1.64%) increase in hospital admissions for URTI at lag 0–3 days, but there were no significant associations with emergency room or outpatient visits. Compared to females, males were more likely to be hospitalized for URTI when the PM2.5 level increased, but other findings did not differ by age group or gender. The study suggests that short-term variations in PM2.5 concentrations have small but detectable impacts on hospital utilization due to URTI in adults.

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“…More in general, the assessment of individual exposures is often derived through averaged values across the monitoring stations at city level or zip-code level [4,12], leading to a possible underestimation of the exposure-outcome relationship [13]. Moreover, time-series or other aggregate study designs have limitations in the ability to assess potential individual effect modifiers, such as smoking habits and occupational exposure [14]. Conversely, the use of data from analytical epidemiological surveys let us overcome these limitations.…”

Section: Introductionmentioning

confidence: 99%

Short-Term Effects of Air Pollution on Cardiovascular Hospitalizations in the Pisan Longitudinal Study

Fasola

Maio

Baldacci

et al. 2021

IJERPH

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Air pollution effects on cardiovascular hospitalizations in small urban/suburban areas have been scantly investigated. Such effects were assessed among the participants in the analytical epidemiological survey carried out in Pisa and Cascina, Tuscany, Italy (2009–2011). Cardiovascular hospitalizations from 1585 subjects were followed up (2011–2015). Daily mean pollutant concentrations were estimated through random forests at 1 km (particulate matter: PM10, 2011–2015; PM2.5, 2013–2015) and 200 m (PM10, PM2.5, NO2, O3, 2013–2015) resolutions. Exposure effects were estimated using the case-crossover design and conditional logistic regression (odds ratio—OR—and 95% confidence interval—CI—for 10 μg/m3 increase; lag 0–6). During the period 2011–2015 (137 hospitalizations), a significant effect at lag 0 was observed for PM10 (OR = 1.137, CI: 1.023–1.264) at 1 km resolution. During the period 2013–2015 (69 hospitalizations), significant effects at lag 0 were observed for PM10 (OR = 1.268, CI: 1.085–1.483) and PM2.5 (OR = 1.273, CI: 1.053–1.540) at 1 km resolution, as well as for PM10 (OR = 1.365, CI: 1.103–1.690), PM2.5 (OR = 1.264, CI: 1.006–1.589) and NO2 (OR = 1.477, CI: 1.058–2.061) at 200 m resolution; significant effects were observed up to lag 2. Larger ORs were observed in males and in subjects reporting pre-existent cardiovascular/respiratory diseases. Combining analytical and routine epidemiological data with high-resolution pollutant estimates provides new insights on acute cardiovascular effects in the general population and in potentially susceptible subgroups living in small urban/suburban areas.

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Long term effect of air pollution on incident hospital admissions: Results from the Italian Longitudinal Study within LIFE MED HISS project

Cited by 70 publications

References 32 publications

A time‐to‐event analysis on air pollutants with the risk of cardiovascular disease and mortality: A systematic review and meta‐analysis of 84 cohort studies

A time‐to‐event analysis on air pollutants with the risk of cardiovascular disease and mortality: A systematic review and meta‐analysis of 84 cohort studies

Fine Particulate Air Pollution and Hospital Utilization for Upper Respiratory Tract Infections in Beijing, China

Short-Term Effects of Air Pollution on Cardiovascular Hospitalizations in the Pisan Longitudinal Study

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