Long-Term Effects of Anxiety on the Metabolic Control of Recently Diagnosed Type 2 Diabetes Patients: Results from the CAIPaDi Cohort Study

Rodríguez-Ramírez, Alejandra Monserrat; Alcántara-Garcés, María Teresa; Hernández-Jiménez, Sergio; García-Ulloa, Ana Cristina; Arcila-Martínez, Denise; Velázquez-Jurado, Héctor; Arizmendi-Rodríguez, Rodrigo Eduardo

doi:10.2147/ndt.s392672

Cited by 3 publications

(2 citation statements)

References 48 publications

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“…Importantly, individuals with T2D are at higher risk of anxiety (20). CBD is known as a potent regulator of inflammation and an effective anxiolytic agent which could help people with T2D to maintain and continue their daily life with higher quality.…”

Section: Discussionmentioning

confidence: 99%

The synergy between cannabidiol and probiotics curtails the glycemic indicators, enhances insulin production, and alleviates the symptoms of type 2 diabetes

Naeini,

Bhandari,

Rogers

et al. 2024

Preprint

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Diabetes continues to challenge healthcare system as one of the most growing epidemics with staggering economic burden. It is estimated that 783 million by 2045 will live with diabetes worldwide, 90% of those cases are type 2 diabetes (T2D). T2D is a multifaceted disease, its treatment requires a holistic approach, beyond single target medications with high efficacy. There is a dire need to explore and invent new and effective therapeutic modalities for T2D.In this study we tested whether a combined formulation of cannabidiol (CBD) and probiotics could control glycemic indices and alleviate symptoms of T2D. We used a mouse model of T2D, replaced their drinking water with a combination of CBD and probiotics formulated as a commercially available beverage.Our findings demonstrated that combination of CBD and probiotics not only reduced the glycemic indices (HbA1c & FBG), but also altered the microbiome profile, promoted beneficial bacteria. Further, the CBD/probiotic combination reduced peripheral inflammatory cytokines and enhanced insulin production in pancreatic islets.In conclusion, our results suggest that consumption of combined CBD and probiotics could be used as a natural, practical, affordable, and safe alternative and complementary therapeutic modality to treat T2D.

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Section: Discussionmentioning

confidence: 99%

The synergy between cannabidiol and probiotics curtails the glycemic indicators, enhances insulin production, and alleviates the symptoms of type 2 diabetes

Naeini,

Bhandari,

Rogers

et al. 2024

Preprint

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show abstract

“…In the subscale "social relations," items highlighted challenges like others finding diabetes unattractive, restricted relationships due to diabetes, social perceptions. In the "emotional worries" subscale, items indicated feeling upset, worried due to diabetes-related issues [14,15,16,17,18] . The "physical complaints" subscale items pointed to pain, skin problems, fatigue, and dry mouth.…”

Section: Discussionmentioning

confidence: 99%

Diabetes-specific quality of life scale (DSQOL): Translation and validation of Urdu short version

Laraib Javaid,

Nasreen Akhtar,

Iffat Batool

et al. 2023

J. Univ. Med. Dent. Coll.

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ABSTRACT BACKGROUND & OBJECTIVE: Quality of life has been affected by numerous psychosocial factors. Thus, for diabetic patients, it was necessary to identify the underlying factors, keeping in view the cultural norms. The objective of the current study was to validate the cultural norms of DSQOL (Diabetes-Specific Quality of Life Scale) through translation into "Urdu" language. METHODOLOGY: A correlational research design was used in the study. Initially, the forward and backward translation method was followed to translate DSQOL. Afterward, the final Urdu translated version (20 items) was tested on a representative sample of 200 diabetic patients to establish its psychometric properties. RESULTS: Internal consistency and correlational matrix of original, Urdu, and English scales yielded reliable results. In the main study, 200 male and female diabetic patients with an age range of 30-70 years and an average of (M±SD;45±8.25) participated. The reliability analysis showed a significant alpha coefficient for five subscales; "Social relations (α= .80), Physical complaints (α=.90), Worries about the future (α= .88), Daily hassles (α= .88), and Emotional worries (α=.87)". The item analysis of Urdu version confirmed the item total correlation of all subscales except three items. Further, CFA confirmed the factor structure of the newly translated Urdu version of DSQOL through AMOS (Analysis of Moment Structure), and the model yielded acceptable model fit indices (CFI=.90; NFI= .90). The Final Urdu version of DSQOL had 20 items. CONCLUSION: The Urdu version of DSQOL is a valid and reliable measure for assessing the diabetics-specific quality of life. This translated tool overcame the cultural barrier with respect to language and norms.

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Differences in mental health status between individuals living with diabetes, and pre-diabetes in Qatar: A cross-sectional study

Mahmoud,

Mahmood

2024

Heliyon

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Long-Term Effects of Anxiety on the Metabolic Control of Recently Diagnosed Type 2 Diabetes Patients: Results from the CAIPaDi Cohort Study

Abstract: Point your SmartPhone at the code above. If you have a QR code reader the video abstract will appear. Or use: https://youtu.be/lpblb_tbnDo

Cited by 3 publications

References 48 publications

The synergy between cannabidiol and probiotics curtails the glycemic indicators, enhances insulin production, and alleviates the symptoms of type 2 diabetes

The synergy between cannabidiol and probiotics curtails the glycemic indicators, enhances insulin production, and alleviates the symptoms of type 2 diabetes

Diabetes-specific quality of life scale (DSQOL): Translation and validation of Urdu short version

Differences in mental health status between individuals living with diabetes, and pre-diabetes in Qatar: A cross-sectional study

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