2023
DOI: 10.21203/rs.3.rs-3236592/v1
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Long-term effects of ipragliflozin on blood pressure in patients with type 2 diabetes: Insights from the randomized PROTECT study

Abstract: Background/Aims Although previous reports have shown that sodium-glucose cotransporter-2 (SGLT2) inhibitors have a blood pressure (BP) lowering effect, relevant long-term data is limited. This study aimed to evaluate the effect of the SGLT2 inhibitor ipragliflozin on BP, and associations between BP reduction and changes in cardiometabolic variables in patients with type 2 diabetes. Methods This was a sub-analysis of the PROTECT (Prevention of atherosclerosis by SGLT2 inhibitor: multicenter, randomized contro… Show more

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