Long-term effects of linoleic-acid-enriched diet on albuminuria and lipid levels in Type 1 (insulin-dependent) diabetic patients with elevated urinary albumin excretion

Dullaart, Robin; Beusekamp, BJ; Meijer, S; Hoogenberg, Klaas; Doormaal, Jasper J. van; Sluiter, Willem

doi:10.1007/bf00402550

Cited by 30 publications

(16 citation statements)

References 41 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Recently, Dullart et al (45) observed that a linoleic-acid-enriched diet prevented the decrease in GFR over a 2-year follow-up period in IDDM patients with elevated UAE patients, which suggests that this kind of diet can alter renal hemodynamics. The increased P/S ratios in the LPD and the test diet do not seem to be related to the observed decrease in GFR, because the reduction in GFR was of a similar magnitude, despite a difference in the P/S ratio in the the two diets.…”

Section: Effect Of Ud Lpd and The Test Diet On Hyperfiltering And Nmentioning

confidence: 97%

Chicken and Fish Diet Reduces Glomerular Hyperfiltration in IDDM Patients

1994

View full text Add to dashboard Cite

show abstract

Section: Effect Of Ud Lpd and The Test Diet On Hyperfiltering And Nmentioning

confidence: 97%

Chicken and Fish Diet Reduces Glomerular Hyperfiltration in IDDM Patients

1994

View full text Add to dashboard Cite

show abstract

“…8 Of 48 included randomised controlled trials in the other review, 24 were included in the current review. Of the remaining 24 randomised controlled trials, 10 did not compare reduced fat intake with usual fat intake (they were included as they modified fat), [53][54][55][56][57][58][59][60][61][62][63] and 13 aimed to reduce weight in some or all participants so were ineligible for the current review. [64][65][66][67][68][69][70][71][72][73][74][75][76] Only one trial was eligible for this review but was not included as no data were provided on body weight, body mass index, or waist circumference.…”

Section: Effects Of Reduced Fat Intake On Body Weightmentioning

confidence: 99%

Effect of reducing total fat intake on body weight: systematic review and meta-analysis of randomised controlled trials and cohort studies

Hooper

Abdelhamid

Moore

et al. 2012

BMJ

250

164

View full text Add to dashboard Cite

Objective To investigate the relation between total fat intake and body weight in adults and children.Design Systematic review and meta-analysis of randomised controlled trials and cohort studies. Inclusion criteria Randomised controlled trials and cohort studies of adults or children that compared lower versus usual total fat intake and assessed the effects on measures of body fatness (body weight, body mass index, or waist circumference) after at least six months (randomised controlled trials) or one year (in cohorts). Randomised controlled trials with any intention to reduce weight in participants or confounded by additional medical or lifestyle interventions were excluded. Data sourcesData extraction Data were extracted and validity was assessed independently and in duplicate. Random effects meta-analyses, subgroups, sensitivity analyses, and metaregression were done.Results 33 randomised controlled trials (73 589 participants) and 10 cohort studies were included, all from developed countries. Meta-analysis of data from the trials suggested that diets lower in total fat were associated with lower relative body weight (by 1.6 kg, 95% confidence interval −2.0 to −1.2 kg, I 2 =75%, 57 735 participants). Lower weight gain in the low fat arm compared with the control arm was consistent across trials, but the size of the effect varied. Metaregression suggested that greater reduction in total fat intake and lower baseline fat intake were associated with greater relative weight loss, explaining most of the heterogeneity. The significant effect of a low fat diet on weight was not lost in sensitivity analyses (including removing trials that expended greater time and attention on low fat groups). Lower total fat intake also led to lower body mass index (−0.51 kg/m 2 , 95% confidence interval −0.76 to −0.26, nine trials, I 2 =77%) and waist circumference (by 0.3 cm, 95% confidence interval −0.58 to −0.02, 15 671 women, one trial). There was no suggestion of negative effects on other cardiovascular risk factors (lipid levels or blood pressure). GRADE assessment suggested high quality evidence for the relation between total fat intake and body weight in adults. Only one randomised controlled trial and three cohort studies were found in children and young people, but these confirmed a positive relation between total fat intake and weight gain. ConclusionsThere is high quality, consistent evidence that reduction of total fat intake has been achieved in large numbers of both healthy and at risk trial participants over many years. Lower total fat intake leads to small but statistically significant and clinically meaningful, sustained reductions in body weight in adults in studies with baseline fat intakes of 28-43% of energy intake and durations from six months to over eight years. Evidence supports a similar effect in children and young people. IntroductionThe optimal intake of total fat was debated at the Joint Food and Agriculture Organization of the United Nations/World Health Organization expert consultation on f...

show abstract

“…Diet composition was estimated with a computer-assisted nutrient database (17). In the dietary intervention trial, butter and saturated margarines were replaced by polyunsaturated margarines, and saturated fat from meat and dairy products was restricted (15). Cholesterol was reduced, but total fat intake was unchanged.…”

mentioning

confidence: 96%

“…In addition, we evaluated whether this polymorphism is a determinant of the lipoprotein response to a linoleic acid-enriched, low-cholesterol diet in type 1 diabetes. viously participated in a diet study and were randomized to increase their dietary polyunsaturated:saturated fatty acids ratio to 1.0 by replacement of saturated fat with linoleic acid (15). Venous blood was obtained after a 10-h fast.…”

mentioning

confidence: 99%

Cholesteryl Ester Transfer Protein Gene Polymorphism Is a Determinant of HDL Cholesterol and of the Lipoprotein Response to a Lipid-Lowering Diet in Type 1 Diabetes

Dullaart¹,

Hoogenberg²,

Riemens³

et al. 1997

Diabetes

View full text Add to dashboard Cite

The TaqIB cholesteryl ester transfer protein (CETP) gene polymorphism (B1B2) is a determinant of HDL cholesterol in nondiabetic populations. Remarkably, this gene effect appears to be modified by environmental factors. We evaluated the effect of this polymorphism on HDL cholesterol levels and on the lipoprotein response to a linoleic acid-enriched, low-cholesterol diet in patients with type 1 diabetes. In 44 consecutive type 1 diabetic patients (35 men), CETP polymorphism, apolipoprotein (apo) E genotype, serum lipoproteins, serum CETP activity (measured with an exogenous substrate assay, n = 30), clinical variables, and a diet history were documented. The 1-year response to diet was assessed in 14 type 1 diabetic patients, including 6 B1B1 and 6 B1B2 individuals. HDL cholesterol was higher in 10 B2B2 than in 14 B1B1 homozygotes (1.63 +/- 0.38 vs. 1.24 +/- 0.23 mmol/l, P < 0.01). HDL cholesterol, adjusted for triglycerides and smoking, was 0.19 mmol/l higher for each B2 allele present. CETP activity levels were not significantly different between CETP genotypes. Multiple regression analysis showed that VLDL + LDL cholesterol was associated with dietary polyunsaturated:saturated fatty acids ratio (P < 0.02) and total fat intake (P < 0.05) in the B1B1 homozygotes only and tended to be related to the presence of the apo E4 allele (P < 0.10). In response to diet, VLDL + LDL cholesterol fell (P < 0.05) and HDL cholesterol remained unchanged in 6 B1B1 homozygotes. In contrast, VLDL + LDL cholesterol was unaltered and HDL cholesterol decreased (P < 0.05) in 6 B1B2 heterozygotes (P < 0.05 for difference in change in VLDL + LDL/HDL cholesterol ratio). This difference in response was unrelated to the apo E genotype. Thus, the TaqIB CETP gene polymorphism is a strong determinant of HDL cholesterol in type 1 diabetes. This gene effect is unlikely to be explained by a major influence on the serum level of CETP activity, as an indirect measure of CETP mass. Our preliminary data suggest that this polymorphism may be a marker of the lipoprotein response to dietary intervention.

show abstract

Long-term effects of linoleic-acid-enriched diet on albuminuria and lipid levels in Type 1 (insulin-dependent) diabetic patients with elevated urinary albumin excretion

Cited by 30 publications

References 41 publications

Chicken and Fish Diet Reduces Glomerular Hyperfiltration in IDDM Patients

Chicken and Fish Diet Reduces Glomerular Hyperfiltration in IDDM Patients

Effect of reducing total fat intake on body weight: systematic review and meta-analysis of randomised controlled trials and cohort studies

Cholesteryl Ester Transfer Protein Gene Polymorphism Is a Determinant of HDL Cholesterol and of the Lipoprotein Response to a Lipid-Lowering Diet in Type 1 Diabetes

Contact Info

Product

Resources

About