Long-term Effects of Oxidative Stress in Volleyball Players

Martinović, Jelena; Dopsaj, Violeta; Dopsaj, M. J.; Kotur‐Stevuljević, Jelena; Vujović, Ana; Stefanović, Aleksandra; Nešić, G

doi:10.1055/s-0029-1238289

Cited by 50 publications

(42 citation statements)

References 23 publications

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“…When the sample is added to the colored solution obtained by mixing a ferric chloride solution with a thiocyanate derivative solution, decoloration results. The intensity of the decoloration is spectrophotometrically detectable at 505 nm and is proportional to the ability of plasma to reduce ferric ions [34], [37]. The results are expressed in µmol/L of the reduced ferric ions.…”

Section: Methodsmentioning

confidence: 99%

Status of Systemic Oxidative Stresses in Patients with Primary Open-Angle Glaucoma and Pseudoexfoliation Syndrome

et al. 2012

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BackgroundThe involvement of local and systemic oxidative stress in intraocular pressure (IOP) elevation and optic nerve damage has been hypothesized in the pathogenesis of glaucoma. To test this, we measured the systemic levels of prooxidants and antioxidants by analyzing the blood biochemistry in patients with glaucoma.MethodsPeripheral blood samples were collected from Japanese patients with primary open-angle glaucoma (PG) (n = 206), exfoliation syndrome (EX) (n = 199), and controls (n = 126). Plasma levels of lipid peroxides, ferric-reducing activity, and thiol antioxidant activity were measured by diacron reactive oxygen metabolites (dROM), biological antioxidant potential (BAP), and sulfhydryl (SH) tests, respectively, using a free radical analyzer.ResultsIn the PG, EX, and control groups, the mean ± standard deviation values were 355±63, 357±69, and 348±56 (U. Carr), respectively, for dROM; 1,951±282, 1,969±252, and 2,033±252 (µmol/L), respectively, for BAP (µmol/L); and 614±98, 584±91, and 617±99 (µmol/L), respectively, for SH. The differences in the BAP values were significant between the PG and control groups (p = 0.0062), for SH between the EX and control groups (p = 0.0017), and for SH between the PG and EX groups (p = 0.0026). After adjustment for differences in age and sex among groups using multiple regression analysis, lower BAP values were correlated significantly with PG (p = 0.0155) and EX (p = 0.0049). Higher dROM values with and without glaucoma were correlated with female gender, and lower SH values with older age. There were no significant differences between the higher (≥21 mmHg) and lower (<21 mmHg) baseline IOPs in the PG group or between the presence or absence of glaucoma in the EX group.ConclusionsLower systemic antioxidant capacity that measured by ferric-reducing activity is involved in the pathogenesis of PG and EX.

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Section: Methodsmentioning

confidence: 99%

Status of Systemic Oxidative Stresses in Patients with Primary Open-Angle Glaucoma and Pseudoexfoliation Syndrome

et al. 2012

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“…In the present study, however, we evaluated oxidative stress and antioxidant potential through all phases of the TH protocol. A proper evaluation of oxidative stress is obtained by measuring the relative balance of oxidative stress and biological antioxidant potential [21, 49], meaning that the measurement of BAP should always form part of this process. …”

Section: Discussionmentioning

confidence: 99%

Status of Systemic Oxidative Stress during Therapeutic Hypothermia in Patients with Post-Cardiac Arrest Syndrome

Dohi

Miyamoto

Fukuda

et al. 2013

Oxidative Medicine and Cellular Longevity

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Therapeutic hypothermia (TH) is thought to be due to the downregulation of free radical production, although the details of this process remain unclear. Here, we investigate changes in oxidative stress and endogenous biological antioxidant potential during TH in patients with post-cardiac arrest syndrome (PCAS). Nineteen PCAS patients were enrolled in the study. Brain temperature was decreased to the target temperature of 33°C, and it was maintained for 24 h. Patients were rewarmed slowly (0.1°C/h, <1°C/day). The generation of reactive oxygen metabolites (ROMs) was evaluated in plasma samples by d-ROM test. Plasma antioxidant capacity was measured by the biological antioxidant potential (BAP) test. Levels of d-ROMs and BAP levels during the hypothermic stage (33°C) were suppressed significantly compared with pre-TH induction levels (P < 0.05), while both d-ROM and BAP levels increased with rewarming (33–36°C) and were correlated with brain temperature. Clinical monitoring of oxidative stress and antioxidant potential is useful for evaluating the redox state of patients undergoing TH after PCAS. Additional therapy to support the antioxidant potential in the rewarming stage following TH may reduce some of the observed side effects associated with the use of TH.

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“…Because the nature of reactive oxygen species is very active, it is difficult to measure them effectively. Recently, oxidative modified molecules and antioxidants were used as reliable parameters for monitoring oxidative stress [9,10]. In this study, we measured AOPP levels, MDA levels and SOD activity to evaluate the oxidative stress status, which is favorable to investigate the relationship between oxidative stress and age-related bone loss.…”

Section: Discussionmentioning

confidence: 99%

“…Superoxide dismutases (SOD) are antioxidant enzymes that disproportionate superoxide to hydrogen peroxide and dioxygen [8]. AOPP, MDA, and SOD were frequently used as the reliable parameters for estimating oxidative stress status [9,10]. Increase of the AOPP and MDA and the decrease of SOD were observed in many patients [11], which suggested that oxidative stress might play an important role in any pathophysiologic processes, including aging [12] and postmenopausal bone loss [7].…”

Section: Introductionmentioning

confidence: 99%