Long-Term Efficacy and Safety of Nebulized Metaproterenol Solution in Bronchial Asthma

Swarts, Charles L.; Hyde, John S.

doi:10.1378/chest.70.5.617

Chest

1976

DOI: 10.1378/chest.70.5.617

|View full text |Cite

Long-Term Efficacy and Safety of Nebulized Metaproterenol Solution in Bronchial Asthma

Charles L. Swarts

John S. Hyde

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...

Citation Types

Supporting

Mentioning

Contrasting

Year Published

1977

1985

Publication Types

Select...

Article5

Relationship

Self Cite0

Independent5

Authors

Journals

Cited by 7 publications

References 1 publication

Supporting

Mentioning

Contrasting

Order By: Relevance

Metaproterenol Solution in the Treatment of Asthmatic Patients by Intermittent Positive Pressure Breathing

Branscomb

1982

The Journal of Clinical Pharma

View full text Add to dashboard Cite

The effects of five different doses of a 5% inhalant solution of metaproterenol on pulmonary function were compared in a placebo-controlled double-blind cross-over study in 40 asthmatic patients who received the drug via intermittent positive pressure breathing (IPPB). The response to metaproterenol in terms of FVC, FEV1, RA, and FEF25-75% was significantly superior to the placebo response. The effect of metaproterenol set in within 5 minutes of adminstration, and clinically significant improvement in pulmonary function was sustained for 6 hours even at the lowest dose level. Global response evaluations reflected a progressive increase in effectiveness with each successive dose increment. Typical sympathomimetic side effects such as nervousness and shakiness slightly increased in frequency with higher doses. At none of the metaproterenol doses were any clinically significant changes observed in the mean blood pressure and pulse rate values.

show abstract

Metaproterenol Solution in the Treatment of Asthmatic Patients by Intermittent Positive Pressure Breathing

Branscomb

1982

The Journal of Clinical Pharma

View full text Add to dashboard Cite

show abstract

Comparison of metaproterenol, isoetharine and salbutamol in the relief of methacholine-induced bronchospasm in dogs

1985

View full text Add to dashboard Cite

show abstract

Bronchodilator characteristics of nebulized metaproterenol sulfate, isoetharine, and atropine in chronic asthma

Ag¹,

Gs²,

Mr³

et al. 1983

Journal of Allergy and Clinical Immunology

View full text Add to dashboard Cite

scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.

Contact Info

customersupport@researchsolutions.com

10624 S. Eastern Ave., Ste. A-614

Henderson, NV 89052, USA

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

Blog Terms and Conditions API Terms Privacy Policy Contact Cookie Preferences Do Not Sell or Share My Personal Information

Made with 💙 for researchers

Part of the Research Solutions Family.

Long-Term Efficacy and Safety of Nebulized Metaproterenol Solution in Bronchial Asthma

Cited by 7 publications

References 1 publication

Metaproterenol Solution in the Treatment of Asthmatic Patients by Intermittent Positive Pressure Breathing

Metaproterenol Solution in the Treatment of Asthmatic Patients by Intermittent Positive Pressure Breathing

Comparison of metaproterenol, isoetharine and salbutamol in the relief of methacholine-induced bronchospasm in dogs

Bronchodilator characteristics of nebulized metaproterenol sulfate, isoetharine, and atropine in chronic asthma

Contact Info

Product

Resources

About