Long-term Efficacy of Repeat Argon Laser Trabeculoplasty

Feldman, Robert M.; Katz, L. Jay; Spaeth, George L.; Crapotta, Joseph A.; Fahmy, Iman; Ali, Moones A

doi:10.1016/s0161-6420(91)32176-6

Cited by 51 publications

(30 citation statements)

References 13 publications

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“…In fact, this could explain the mixed success of repeated argon LT, in that the thermal damage of argon LT may exceed the therapeutic effects upon retreatment. The results of repeated treatments of argon LT are inconsistent, ranging from unsuccessful to approximately 70% successful 1 year after retreatment [24,50]. The higher rates of success are usually seen in cases that previously showed at least 1 year of success following initial treatment of argon LT [50].…”

Section: Discussionmentioning

confidence: 99%

“…The results of repeated treatments of argon LT are inconsistent, ranging from unsuccessful to approximately 70% successful 1 year after retreatment [24,50]. The higher rates of success are usually seen in cases that previously showed at least 1 year of success following initial treatment of argon LT [50]. Unfortunately, the success or retreatment is short-term, with IOP controlled in 11-15% of cases at 2 years, and with IOP controlled in none at 5 years [50].…”

Section: Discussionmentioning

confidence: 99%

“…The higher rates of success are usually seen in cases that previously showed at least 1 year of success following initial treatment of argon LT [50]. Unfortunately, the success or retreatment is short-term, with IOP controlled in 11-15% of cases at 2 years, and with IOP controlled in none at 5 years [50]. In contrast, there are no studies showing the success of repeat diode laser trabeculoplasty.…”

Section: Discussionmentioning

confidence: 99%

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Optical properties of human trabecular meshwork in the visible and near-infrared region

et al. 1999

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

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Optical properties of human trabecular meshwork in the visible and near-infrared region

et al. 1999

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“…The incidence of iritis, post-laser IOP spikes, and peripheral anterior synechiae is significantly reduced with SLT compared to ALT [71][72][73]. Furthermore, the lack of trabecular meshwork scarring makes SLT more amenable to repeat treatment [4,[74][75][76][77].…”

Section: Selective Laser Trabeculoplasty As Initial Treatmentmentioning

confidence: 99%

Laser Trabeculoplasty and Aqueous Dynamics

Lee¹,

Rahmatnejad²,

Waisbourd³

et al. 2016

Glaucoma - Intraocular Pressure and Aqueous Dynamics

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For the past four decades, laser trabeculoplasty has been a staple in the treatment armamentarium against glaucoma. Although the exact mechanism of laser trabeculoplasty has not been fully elucidated, its clinical utility in lowering intraocular pressure has been well established. Aqueous dynamic studies uniformly reveal an increase in aqueous outflow facility at the trabecular meshwork. Accumulating evidence suggests that the mechanism is the result of complex cellular and biochemical processes. Histopathological studies of the trabecular meshwork tissue after argon laser suggest an additional mechanical role. The traditional treatment algorithm for glaucoma placed laser trabeculoplasty as an intermediary between medical therapy and incisional surgery. However, because of the safety profile of selective laser trabeculoplasty, recent studies have challenged this treatment paradigm. One such study was a multicenter trial headed by our department that compared laser trabeculoplasty and medical therapy as initial treatment for glaucoma. We showed a similar efficacy between the two modalities, reinforcing the possibility of using laser as the initial treatment in the right clinical setting.

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“…Argon laser trabeculoplasty (ALT) is a parasurgical technique that allows to reduce the IOP; the success rate is high (70–80%), but it reduces after some years (56% at 2 years, 30–50% at 5 years, 5–30% at 10 years) [2,3,4,5,6]. Retreatment can be performed, but it has a lower success rate [7]. The more recent selective laser trabeculoplasty has a similar efficacy [8,9,10,11].…”

Section: Introductionmentioning

confidence: 99%

Pneumatic Trabeculoplasty versus Argon Laser Trabeculoplasty in Primary Open-Angle Glaucoma

Uva

Longo²,

Reibaldi³

2009

Ophthalmologica

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Aims: To compare the efficacy of pneumatic trabeculoplasty (PNT) and argon laser trabeculoplasty (ALT) in primary open-angle glaucoma (POAG) uncontrolled with two topical therapies. Methods: In a randomized, prospective clinical study, 32 patients received in 1 eye PNT or ALT. Results: At 1 month, in PNT- and in ALT-treated eyes respectively, mean intraocular pressure (IOP) decreased by 3 ± 2.3 and 5.7 ± 1.7 mm Hg (12.7 ± 9.6 and 24.4 ± 7.4%, both paired t test p < 0.001); 5 and 13 eyes (31 vs. 81%, χ² test p = 0.013) had an IOP reduction ≥20%, 7 and 1 eyes had an insufficient effect (IOP >20 mm Hg). Only 1 PNT-treated eye had IOP reduction ≥20% until 4 months. At 6 months, 10 ALT-treated eyes (62.5%) had IOP reduction ≥20%; 15 PNT- and 3 ALT-treated eyes had an insufficient effect (94 vs. 19%, p < 0.001). Transient anterior segment side effects, but not visual field or fundus changes, occurred after both treatments. Conclusions: PNT is less effective than ALT in POAG uncontrolled with two topical therapies.

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Long-term Efficacy of Repeat Argon Laser Trabeculoplasty

Cited by 51 publications

References 13 publications

Optical properties of human trabecular meshwork in the visible and near-infrared region

Optical properties of human trabecular meshwork in the visible and near-infrared region

Laser Trabeculoplasty and Aqueous Dynamics

Pneumatic Trabeculoplasty versus Argon Laser Trabeculoplasty in Primary Open-Angle Glaucoma

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