Long-Term Evaluation of Low-Density Cement: Laboratory Studies and Field
Application

Al-Yami, Abdullah; Nasr‐El‐Din, Hisham A.; Al-Saleh, Salah; Al-Humaidi, Ahmed S.; Miller, Clayton; Al-Yami, Hussein Eidah; Elmarsafawi, Youssef

doi:10.2523/105340-ms

Cited by 3 publications

(4 citation statements)

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“…A single center retrospective study comparing the nephrotoxicity of vancomycin plus meropenem in 75 patients with vancomycin plus piperacillin-tazobactam in 108 patients was unable to demonstrate statistical significance. 7 However, the results of another prospective study demonstrated statistical significance in comparing AKI in a group that had received vancomycin plus either meropenem or cefepime with a group that received PT-vancomycin. 14 The specific mechanism of action linking increased incidence of AKI with the combination of PT-vancomycin remains unknown.…”

Section: Discussionmentioning

confidence: 98%

“…5 It has only recently been demonstrated that the combination of piperacillin-tazobactam with vancomycin can further increase the risk of nephrotoxicity. [7][8][9][10][11][12][13][14][15][16][17][18] Renal function is often measured by serum creatinine, and an acute increase often represents kidney failure. 19 It has been previously shown that an increase in serum creatinine (SCr) of >/= 0.5mg/dl is associated with increased odds of death by 6.5 times, an average increased length of stay (LOS) of 3-5 days, and increased hospital costs of $7500.…”

Section: Introductionmentioning

confidence: 99%

“…A possible alternative initial therapy for sepsis that would cover MRSA and pseudomonas aeruginosa might include vancomycin and meropenem (brand name Merrem). 7 Meropenem is a carbapenem and part of the beta lactam family of antibiotics. It has a spectrum of coverage similar to piperacillin-tazobactam and has a rate of creatinine increase of less than 1%.…”

Section: Introductionmentioning

confidence: 99%

“…21 To our knowledge, only two other published studies have examined the rate of acute kidney injury (AKI) occurring when a carbapenem is combined with vancomycin across multiple disease states. 7,14 The purpose of this retrospective study was to investigate whether the risk of AKI was greater in a convenience sample of hospitalized patients receiving the combination of piperacillin-tazobactam with vancomycin verses meropenem with vancomycin.…”

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Comparison of Acute Kidney Injury During Treatment with Vancomycin and either Piperacillin-Tazobactam or Meropenem

Cannon

Douce

Grubbs

et al. 2017

Spartan Medical Research Journal

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CONTEXT CONTEXT Empiric antibiotics are often required in hospitalized patients with serious infections who may be septic and at risk for drug resistant organisms. The purpose of this study was to evaluate the observed incidence of acute kidney injury (AKI) in a sample of adult patients receiving either piperacillin-tazobactam and vancomycin or meropenemvancomycin for at least 72 hours. METHODS METHODS Single-center, retrospective matched cohort at a 200-bed Regional Community Medical Center. Adult patients were included in the sample if they were without preexisting renal dysfunction and admitted over an 18-month time period to receive either the combination of piperacillin-tazobactam and vancomycin or meropenem-vancomycin. Sample patients were evaluated for AKI. This condition was defined by the authors as an increase in serum creatinine of 0.5mg/ml or an increase of 50% above baseline during the duration of antibiotic treatment. RESULTS RESULTS A total of 266 patients receiving either combination of antibiotics were evaluated for AKI. The incidence of AKI was significantly higher in the piperacillin-tazobactam and vancomycin group (n = 74/292, 25%) compared with the meropenem-vancomycin group (n=8/74, 9.5%, p=0.008). CONCLUSIONS CONCLUSIONS The results of this study suggest that the combination of piperacillin-tazobactam and vancomycin is associated with an increased incidence of AKI. Higher vancomycin trough concentrations were associated with increased risk for development of AKI.

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Section: Discussionmentioning

confidence: 98%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Comparison of Acute Kidney Injury During Treatment with Vancomycin and either Piperacillin-Tazobactam or Meropenem

Cannon

Douce

Grubbs

et al. 2017

Spartan Medical Research Journal

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Cement Failure Probability under HPHT Conditions Supported by Long Term Lab Studies and Field Cases

Yuan

Al-Yami

Schubert

et al. 2012

SPE Annual Technical Conference and Exhibition

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Cement durability is very important to maintain proper well isolation and stability under HPHT conditions. In the process of well completion and production, pressure decline and temperature variation with time can contribute to cement failure and wellbore stability issues. However, there is no available investigation in the durability and comparison of different types of cement at higher temperature and at different operational scenarios. Three different types of cement (72 pcf, 101 pcf and 118 pcf) commonly used in the Middle East were cured and tested at 300°F in the study. The tests included one year mechanical properties measurement such as compressive strength development, Young's modulus and Poisson's ratio. Finite element method was used to analyze the failure probability of HPHT wells over with time. At the variation of bottom hole pressure and temperature, the casing, cement, and formation system failure probability was studied for these types of cement. The results show that the pressure variation has more effect on the wellbore stability than the temperature variation for HPHT wells. Low density cement can improve the wellbore stability issues due to the cement elastic behavior. This paper introduces the operational envelope for every type of cement investigated in order to achieve successful operations based on field conditions. Field cases were discussed to validate the results of this investigation.

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Failure Probability with Time under Different Operational Conditions for Low-Density System Based on Hollow Microspheres Supported By Long Term Lab Studies and Field Cases

Al-Yami

Yuan

Schubert

2012

SPE Asia Pacific Oil and Gas Conference and Exhibition

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Cementing a string in one stage is a challenging task, especially in the presence of weak formations. Cement slurry losses during placement is highly possible if the equivalent circulating density (ECD) exceeds 82 pcf during placement. A conventional method to overcome this challenge is to use multi-stage cementing by setting the stage tool above the loss circulation zone. However, field data indicate that the tool can fail, thus causing serious delay and economic loss. In addition, stage tools are considered weak point and not good for long term seal. A second method for zonal isolation is to use low density cement.In this study, we present extensive lab evaluation of a low density system based on the use of hollow microspheres for one year at field conditions. The tests included one year mechanical properties measurement such as compressive strength development, Young's modulus and Poisson's ratio. The low-density system (70 pcf) was tested at 300 ºF. An earlier study has shown the suitability of using low density cement in the field, Al-Yami et al. (2007). However, there is no available Investigation in the literature about the durability of low density cement at higher temperature and at different operational scenarios.The finite element method was used to analyze the failure probability of HPHT wells over with time. At the variation of bottom whole pressure, the casing, cement, and formation system failure probability was studied for this type of cement. This paper introduces the operational envelope for this type of cement in order to achieve successful operations. Field cases were discussed to validate the results of this investigation.

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Long-Term Evaluation of Low-Density Cement: Laboratory Studies and Field Application

Cited by 3 publications

References 0 publications

Comparison of Acute Kidney Injury During Treatment with Vancomycin and either Piperacillin-Tazobactam or Meropenem

Comparison of Acute Kidney Injury During Treatment with Vancomycin and either Piperacillin-Tazobactam or Meropenem

Cement Failure Probability under HPHT Conditions Supported by Long Term Lab Studies and Field Cases

Failure Probability with Time under Different Operational Conditions for Low-Density System Based on Hollow Microspheres Supported By Long Term Lab Studies and Field Cases

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