Long-term evaluation of pain reduction after vertebroplasty and kyphoplasty

Abstract

Background Various studies have been made about the most effective and safest type of treatment for vertebral compression fractures (VCFs). Long-term results are needed for qualitative evaluation. Purpose The purpose of the study is to evaluate the effectiveness of percutaneous vertebroplasty (PVP) and percutaneous kyphoplasty (PKP) procedures for VCFs. Materials and Methods Forty-nine patients who received either PVP or PKP between 2002 and 2015 returned a specially developed questionnaire and were included in a cross-sectional outcome analysis. The questionnaire assessed pain development by use of a visual analog scale (VAS). Imaging data (CT scans) were retrospectively analyzed for identification of cement leakage. Results Patients’ VAS scores significantly decreased after treatment (7.0 ± 3.4 => 3.7 ± 3.4), ( p < 0.001). The average pain reduction in patients treated with PVP was −3.3 ± 3.8 ( p < 0.001) (median −3.5) and −4.0 ± 3.9 ( p < 0.001) (median −4.5) in patients treated with PKP. Fifteen Patients (41.7%) receiving PVP and four patients (30.7%) receiving PKP experienced recurrence of pain. Cement leakage occurred in 10 patients (22.73%). Patients with cement leakage showed comparable VAS scores after treatment (6.8 ± 3.5 => 1.4 ± 1.6), ( p = 0.008). Thirty-nine patients reported an increase in mobility (79.6%) and 41 patients an improvement in quality of life (83.7%). Conclusion Pain reduction by means of PVP or PKP in patients with VCFs was discernible over the period of observation. Percutaneous vertebroplasty and PKP contribute to the desired treatment results. However, the level of low pain may not remain constant.

Analysis of Clinical Outcomes of Percutaneous Kyphoplasty and Vertebroplasty in the Treatment of Osteoporosis-Induced Vertebral Compression Fracture

“…We assessed how well the treatment's effects were examined on osteoporotic VCFs. We showed that PVP and PKP considerably reduce pain in patients with VCFs by evaluating the data gathered to evaluate patient outcomes [12]. Our analysis included patient data from interventional treatment administered between January and December of 2020, with an average one-year gap between treatment and clinical evaluation.…”

“…The visual analogue scale (VAS score 0-10; 0 no pain at all; 10 the worst imaginable) system was employed to evaluate back pain control. Impact on the patient's daily life was assessed using the Oswestry Disability Index (ODI) questionnaire [11,12]. Radiographs were taken to measure the rate of cement leakages and refracture, the anterior, middle and posterior vertebral heights, Cobb's angle and Vertebral wedge ratio [11] of the fractured vertebral body before and after surgery.…”

Clinical analysis of osteoporotic vertebral oblique compression fracture treated with bone cement combined with balloon

“…The majority of OVCF patients mainly showed the loss of anterior vertebral height and the increase of kyphotic angle on X-ray lateral lms, while OVOCF patients showed the serious loss of vertebral height and the increase of vertebral scoliosis angle on X-ray lateral lms. Both bone cement and bone cement combined with balloon have achieved signi cant clinical e cacy in the treatment of OCVF induced spinal pain, and their main roles are to restore vertebral height and strength, correct kyphosis, and rebuild spinal stability 22,23 . In the past, when they were used to treat OVCF, only the sagittal height of vertebral body was restored, and kyphosis was corrected 24 .…”

The Burden of Metastatic Cancer–Induced Bone Pain: A Narrative Review

“… 30 , 41 , 70 , 71 However, recent data on the impact of kyphoplasty or vertebroplasty on HRQOL are limited, and vertebroplasty is controversial, as studies on its efficacy in reducing mCIBP are mixed. 72–75 A 2021 publication reported that, in patients with cancer pain due to bone metastases, pain was significantly reduced and HRQOL was significantly improved up to 6 months after either radiofrequency ablation alone or radiofrequency ablation with vertebroplasty. 76 …”

“…30,41,70,71 However, recent data on the impact of kyphoplasty or vertebroplasty on HRQOL are limited, and vertebroplasty is controversial, as studies on its efficacy in reducing mCIBP are mixed. [72][73][74][75] A 2021 publication reported that, in patients with cancer pain due to bone metastases, pain was significantly reduced and HRQOL was significantly improved up to 6 months after either radiofrequency ablation alone or radiofrequency ablation with vertebroplasty. 76 Surgery is an option for serious complications of bone metastases, including restoration of function because of spinal instability or impending spinal instability and pain that is intractable or was not relieved by nonsurgical therapy.…”