Long term follow-up of 799 children with isolated ventricular septal defects

Erdem, Sevcan; Özbarlas, Nazan; Küçükosmanoğlu, Osman; Poyrazoğlu, Hakan; Salih, Orhan Kemal

doi:10.5543/tkda.2012.01679

Cited by 11 publications

(12 citation statements)

References 18 publications

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“…From a clinical point of view, interpretation of data may be challenging. It is known that in case of large to moderate perimembranous and subarterial VSDs follow‐up is warranted for possible complications such as aortic valve prolapse, aortic regurgitation left ventricle‐to‐right atrium shunt, subaortic ridge, and infundibular stenosis . We did not experience similar complications but our series involved mainly small VSDs, with the follow‐up of only two large and 19 moderate sized VSDs.…”

Section: Discussionmentioning

confidence: 85%

See 1 more Smart Citation

Incidence and natural history of neonatal isolated ventricular septal defects: Do we know everything? A 6-year single-center Italian experience follow-up

Cresti

Giordano

Koestenberger

et al. 2017

Congenital Heart Disease

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Section: Discussionmentioning

confidence: 85%

“…Other studies, instead, have a limited follow‐up period . There are only few studies evaluating the natural history of all types of neonatal VSDs and with a long follow‐up period (ie, >2 years) …”

Section: Discussionmentioning

confidence: 99%

Incidence and natural history of neonatal isolated ventricular septal defects: Do we know everything? A 6-year single-center Italian experience follow-up

Cresti

Giordano

Koestenberger

et al. 2017

Congenital Heart Disease

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“…The results from the data confirmed that the ratio of the diameter of the aorta to that of the pulmonary artery in TOF is disproportional due to the uneven separation of the circular trunk. Growth of the pulmonary artery is limited, while that of the aorta is fast 7 . Therefore, the ratio of the aortic diameter to the pulmonary artery diameter is increased significantly.…”

Section: Discussionmentioning

confidence: 99%

Differential diagnosis of fetal large ventricular septal defect and tetralogy of Fallot based on big data analysis

Yang

et al. 2020

Echocardiography

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Background and Objectives:To analyze echocardiographic parameters of fetal large ventricular septal defect (VSD) and tetralogy of Fallot (TOF) in the context of multicenter data and big data analysis because these two diseases are often misdiagnosed in fetuses, and to find the key parameters for the differential diagnosis of these two diseases.Methods: A total of 305 cases of large VSD and 192 cases of TOF diagnosed by fetal echocardiography from August 2010 to July 2016 from the database of Beijing Key Laboratory of Fetal Heart Defects were analyzed. Quantile regression of the 48 echocardiographic parameters of the 6272 normal fetuses from seven Chinese medical institutions was performed to determine the Q-score. The forward selection method and the naive Bayesian classification method were used to analyze the core differential diagnostic variables of fetal TOF and VSD. Results:The Q-score of the internal diameter of the aorta (AO Q-score), the ratio of the diameter of the pulmonary artery to the internal diameter of the aorta (PA/AO), and the Q-score of the ratio of the diameter of the pulmonary artery to the internal diameter of the aorta (PA/AO Q-score) were key parameters for the differential diagnosis of fetal large VSD and TOF. PA/AO was the primary parameter, with an area under the receiver operating characteristic curve of 0.951. Conclusions: These findings provide a new method for the prenatal diagnosis of large VSD and TOF and a theoretical basis for the intelligent diagnosis of large VSD and TOF. K E Y W O R D S big data analysis, fetal echocardiography, fetal large ventricular septal defect, tetralogy of fallot | 621 LV et aL. How to cite this article: Lv J, Yang T, Gu X, et al. Differential diagnosis of fetal large ventricular septal defect and tetralogy of Fallot based on big data analysis. Echocardiography.

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“…Closure occurred most frequently at the midmuscular location, while apical defects persisted more often (7,8). Age at first echocardiographic examination and the length of the follow-up period may influence the spontaneous closure rate (9,10). It has been demonstrated that 12.5-31% of m-VSDs can undergo spontaneous closure during fetal life (11,12).…”

Section: Discussionmentioning

confidence: 99%

Natural history of prenatal isolated muscular ventricular septal defects

Erol¹,

Şevket²,

Keskın³

et al. 2014

J Turkish German Gynecol Assoc

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Results:Of the 76 cases with m-VSD, 1 fetus died after birth and 31 cases were lost to follow-up after birth. Thus, a total of 44 fetuses reached their first year of postnatal life, and these cases were available for analysis. Three (6.8%) of 44 defects closed spontaneously in utero, 33 (75%) closed within 1 year, and 8 (18.2%) remained patent. Overall, spontaneous closure occurred more frequently in the apical defects, but no significant difference was found for spontaneous closure between the mid-muscular and apical defects (p>0.05). Also, 83.8% (36 of 44) of defects ≤3 mm closed during gestation or the first year of life. Key words: Isolated, muscular ventricular septal defect, spontaneous closure Received: 15 January, 2014 Accepted: 11 March, 2014 Natural history of prenatal isolated muscular ventricular septal defects Conclusion:

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Long term follow-up of 799 children with isolated ventricular septal defects

Abstract: Our data on the natural course and prognosis of VSDs may be of relevance with respect to patients' age, defect type, and complications encountered in the follow-up period.

Cited by 11 publications

References 18 publications

Incidence and natural history of neonatal isolated ventricular septal defects: Do we know everything? A 6-year single-center Italian experience follow-up

Incidence and natural history of neonatal isolated ventricular septal defects: Do we know everything? A 6-year single-center Italian experience follow-up

Differential diagnosis of fetal large ventricular septal defect and tetralogy of Fallot based on big data analysis

Natural history of prenatal isolated muscular ventricular septal defects

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