Long-Term Follow-up of Artificial Valves in Patients under 15 Years Old

Wada, J; Yokoyama, Masayoshi; Hashimoto, A; Imai, Yasuharu; Kitamura, Nobuo; Akiyama, Takayuki; Momma, Kazuo

doi:10.1016/s0003-4975(10)61696-7

Cited by 51 publications

(9 citation statements)

References 4 publications

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“…The low reoperation rate in group I can be explained by the fact that earlier valvuloto my in group 1 may have slowed the progression of the thickening and calcification of the valve as also mentioned by others ( 14,25). There are several reports about enlargement procedures of the narrow aortic annulus (18,21,23) and studies about valve replacement in children (7,12,18,21,23,28,33,35). However, the ideal heart valve substitute does not yet exist (4,12,13) and late complications occur freq uently (35) .…”

Section: Discussionmentioning

confidence: 72%

Congenital Aortic Stenosis. Early and Late Results of Aortic Valvulotomy

Kugelmeier¹,

Egloff²,

Real³

et al. 1982

Thorac cardiovasc Surg

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Between 1962 and 1979, 87 patients with congenital aortic stenosis (11 infants from 4 days to 5 months, and 76 patients from one year to 24 years) underwent open aortic valvulotomy; in 14 patients an additional subvalvular membraneous ring or hypertrophic subaortic stenosis was resected. There were 3 early deaths (3%), all in infants less than one year of age. A second operation was necessary 3 months to 10 years (mean 6.3 +/- 4 years) after the initial procedure in 12 of the 84 survivors. In 9 patients an aortic valve replacement and in 3 patients a second valvulotomy was performed without perioperative mortality: in the latter group valve replacement had to be performed later. There were 5 late deaths (6%). The causes of death were endocarditis (2), thrombosis of the prosthesis (1), accident (1) and sudden death (1). The overall actuarial survival curve shows a 5-year survival of 90% and a 10-year survival of 87%; 87% are reoperation-free after 5 years and 75% after 8 years. At present 7 patients are scheduled for surgery because of recurrence of stenosis; 61 patients are symptom-free. It is concluded that aortic valvulotomy has immediate and long-term benefit in the large majority of patients. Operative mortality and morbidity are low in patients older than one year of age. Nevertheless aortic valvulotomy, which should not be performed too late, represents a palliative treatment and will lead to reoperation in approximately 25% of patients after 8 years.

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Section: Discussionmentioning

confidence: 72%

Congenital Aortic Stenosis. Early and Late Results of Aortic Valvulotomy

Kugelmeier¹,

Egloff²,

Real³

et al. 1982

Thorac cardiovasc Surg

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“…Despite these concerns, xenografts have already been implanted into the central nervous system of patients with Parkinson's disease 76 -82 and avascular xenografts of porcine tissue have been used for cardiac valve transplantation. [83][84][85][86] The role of xenografts in the management of RPEmediated disease or dysfunction remains to be determined.…”

Section: Barriers To Successful Rpe Transplantationmentioning

confidence: 99%

Triple Immune Suppression Increases Short-Term Survival of Porcine Fetal Retinal Pigment Epithelium Xenografts

Priore

Ishida

Johnson³

et al. 2003

Invest. Ophthalmol. Vis. Sci.

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“…Materials of the scent was also changed from polypropylene to Derline (ultrahigh molecular weight polyethylene) to reduce fatigue stress of leaflets (Carpentier et al 1982;Wright et al 1982). Calcification of the xenograft valve, especially in children has been a major problem (Kutsche et al 1979;Silver et al 1980;Thandroyen et al 1980 ;Wada et al 1980 ;Kagawa et al 1982Kagawa et al , 1984. The result of calcium mitigation with use of surfactant in animal experiments was reported by Arbustini (Arbustini et al 1984), which revealed decrease in calcification of porcine valve implanted in the tricuspid position of a sheep.…”

Section: Discussionmentioning

confidence: 99%

“…Though durability of porcine xenograft valve is not known entirely, there were many reports regarding the good valvular functions in the adults, as the intermediate results were obtained (Hannah and Reis 1976;Cevesc et al 1977;Lurie et al 1977;Angell et al 1979;Cohn et al 1979). On the contrary, high incidence of calcification of xenograft valves, especially in children (Kutsche et al 1979;Silver et al 1980;Thandroyen et al 1980;wada et al 1980;Kagawa et al 1982Kagawa et al , 1984 and valvular malfunction due to primary tissue failure in adults (McIntosh et al 1975;Brown et al 1978;Grehl et al 1981;Kagawa et al 1984) were also reported. Furthermore, slight suspicions for antithrombogencity, which was regarded as the biggest advantage of porcine xenograft valves were also incured (Stinson et al 1974;Jamieson et al 1981).…”

mentioning

confidence: 99%