“…Borrowing from the surgical paradigm, suturing and stapling strategies have been applied to attempts at transoral gastrojejunostomy creation, but these strategies either have not progressed beyond animal studies 5,6 or have required significant laparoscopic assistance. 7,8 A third strategy based on compression anastomosis has been proven multiple times in the porcine model, [9][10][11] and magnetic compression in particular has also been used in a human trial as a minimally invasive treatment of malignant gastric outlet obstruction. 12 However, compression anastomoses have historically had 2 major disadvantages: (1) they require days to form 13 and (2) transoral delivery of the device has restricted anastomotic size (in the literature, maximum diameter is 1.4 cm), which in turn has limited long-term patency.…”