Long-term follow-up of nineteen cystic lymphangiomas treated with fibrin sealant

Sclerotherapy for cervical cystic lymphatic malformations in children. Our experience with computed tomography-guided 98% sterile ethanol insertion and a review of the literature

“…Another limit of OK-432 is the risk of an adverse reaction in patients with a penicillin G allergy and difficulties in acquiring the substance. In 1991, Castañon et al [31] noted that injection of fibrin glue (Tissucol) inside the lymphatic cyst was followed by adhesion of the cystic surfaces. Recently, an alcoholic solution of zein (Ethibloc) has been proposed as a sclerosing agent for lymphatic malformations.…”

Alcoholic solution of zein (Ethibloc) sclerotherapy for treatment of lymphangiomas in children

“…Simple puncture, irradiation, and chemotherapy have been tried and abandoned. Intracystic injection of sclerosing agents has been used in recent years [6,[11][12][13][14][15][16][17][18][19]. The main substances used were bleomycin, doxycyclin, OK-432, Fibrin sealant, and Ethibloc.…”

Management of cystic lymphangioma in children: experience in Jos, Nigeria

“…This confirms the historical results achieved by most major surgical centers and the reasons why alternative methods are sought. In most pediatric centers surgical excision, either partial or complete, has been replaced by alternative non-surgical methods of management, i.e., sclerosing therapy with bleomycin, 0K432 and others [11][12][13][14]. We, however, do not have experience with this treatment modality at the moment but plans for a trial are underway.…”