Long-term follow-up of porcine dermis pubovaginal slings

Broussard, Andre P.; Reddy, Thanmaya; Frilot, Clifton; Kubricht, William S.; Gomelsky, Alex

doi:10.1007/s00192-012-1919-4

Cited by 7 publications

(6 citation statements)

References 17 publications

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“…Outcomes for xenograft porcine dermis slings were poor. For example, a multicentre prospective randomized control trial (RCT) suspended its porcine dermis arm owing to clear inferiority to both autologous and synthetic slings [46][47][48][49]. Additionally, xenograft RCTs for POP compared porcine dermis, porcine small intestine submucosa and bovine pericardium with traditional anterior repairs 1-3 years after surgery and demonstrated biological material superiority in two studies [50,51] and no anatomic benefit in the rest [52][53][54][55][56].…”

Section: Clinical Findingsmentioning

confidence: 99%

Managing female pelvic floor disorders: a medical device review and appraisal

2019

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Pelvic floor disorders (PFDs) will affect most women during their lifetime. Sequelae such as pelvic organ prolapse, stress urinary incontinence, chronic pain and dyspareunia significantly impact overall quality of life. Interventions to manage or eliminate symptoms from PFDs aim to restore support of the pelvic floor. Pessaries have been used to mechanically counteract PFDs for thousands of years, but do not offer a cure. By contrast, surgically implanted grafts or mesh offer patients a more permanent resolution but have been in wide use within the pelvis for less than 30 years. In this perspective review, we provide an overview of the main theories underpinning PFD pathogenesis and the animal models used to investigate it. We highlight the clinical outcomes of mesh and grafts before exploring studies performed to elucidate tissue level effects and bioengineering considerations. Considering recent turmoil surrounding transvaginal mesh, the role of pessaries, an impermanent method, is examined as a means to address patients with PFDs.

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Section: Clinical Findingsmentioning

confidence: 99%

Managing female pelvic floor disorders: a medical device review and appraisal

2019

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“…Concerns regarding antigenicity and transmission of infection, such as HIV and slow viruses including Creutzfeld-Jacob disease, have been raised [40]. Xenogenic grafts include porcine dermis and small bowel porcine submucosa (SIS) also have been used as alternative grafts with lower success rates [46]. Synthetic slings were developed to avoid wound morbidity but had the risk of vaginal or urethral erosion.…”

Section: Introductionmentioning

confidence: 99%

Joint report on the terminology for surgical procedures to treat stress urinary incontinence in women

2020

Int Urogynecol J

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Introduction and hypothesis Standardized terminology for surgical procedures commonly performed to treat stress urinary incontinence in women is needed to facilitate research, clinical care, and teaching in female pelvic medicine and reconstructive surgery. Methods This report combines the input of members of the American Urogynecologic Society and the International Urogynecological Association, assisted by external referees. Extensive searches of the literature were performed, including Instructions for Use brochures and original source documents where possible. Historical context was considered along with procedural modifications, and expert opinion was included when appropriate. Results A terminology report for the procedures commonly performed to treat stress urinary incontinence in women was produced. Included procedures are midurethral sling, retropubic colposuspension, pubovaginal sling, urethral bulking, and artificial urinary sphincter. Appropriate figures have been included to supplement and help clarify the text. Ongoing review will be performed periodically to keep the document updated and widely acceptable. Conclusions This document is a literature and consensus-based terminology report for surgical procedures to treat stress urinary incontinence in women. Future publications in female pelvic medicine and reconstructive surgery should use this standardized terminology whenever possible.

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“…Although the concomitant placement of a second sling should theoretically enhance continence after primary sling removal, this was not observed in the present study. One explanation for these disappointing results could be the fact that the collagen sling used seems to be less effective in curing SUI in the long term by comparison with conventional polypropylene tapes [21]. However, when considering that the present study population involved patients who experienced postoperative complications, the results should not be compared with those of studies in which the Pelvilace collagen sling was used as a primary sling.…”

Section: Discussionmentioning

confidence: 89%