Long-term follow-up of renal donors

Do Biochemical Measures Change in Living Kidney Donors?

“…Romero et al [26] did not report pre- and postnephrectomy values, but did note that uric acid levels were within the normal range both before, and up to 5 months after surgery. Similarly, Undurraga et al [29] did not provide pre- and postdonation values, but did note that 30% of the donors developed hyperuricemia (defined in the study as uric acid >446 µmol/l).…”

“…Eight studies, published from 1982 to 2005, described a biochemical outcome of interest in donors at least 4 months after uninephrectomy [19,22,23,24,25,26,27,28,29] (table 1). All identified studies either compared donors before and after donation, or compared donors with select controls.…”

“…Three studies compared donors before and after uninephrectomy on changes in uric acid metabolism [24, 26, 29]. One study provided control group data [29].…”

“…One study provided control group data [29]. Hida et al [24] observed a 24% increase in uric acid levels after donation, however, these levels still remained within the normal range.…”

Imputing variance estimates do not alter the conclusions of a meta-analysis with continuous outcomes: a case study of changes in renal function after living kidney donation

“…Only 13 studies reported a P-value or test statistic for at least one outcome [11,12,14,18,19,23,25,26,31,35,37,42,48]. All outcomes had at least one P-value or test statistic reported.…”