1995
DOI: 10.1016/0142-9612(95)91093-e
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Long-term histological evaluation of hydroxyapatite ceramics in humans

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Cited by 65 publications
(33 citation statements)
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“…All reagents were purchased from Wako Pure Chemical Industries (Osaka, Japan) and used without further purification. Sintered synthetic hydroxyapatite (APACERAM; Asahi Optical Co., Tokyo, Japan) with a Ca/P ratio of 1.67 26 was used as standard hydroxyapatite. Nylon (nylon-6) fabric, a standard adjacent fabric conforming to Japanese Industrial Standards (JIS) (Dyeing and Finishing), was used as the control for the polypeptide.…”
Section: Methodsmentioning
confidence: 99%
“…All reagents were purchased from Wako Pure Chemical Industries (Osaka, Japan) and used without further purification. Sintered synthetic hydroxyapatite (APACERAM; Asahi Optical Co., Tokyo, Japan) with a Ca/P ratio of 1.67 26 was used as standard hydroxyapatite. Nylon (nylon-6) fabric, a standard adjacent fabric conforming to Japanese Industrial Standards (JIS) (Dyeing and Finishing), was used as the control for the polypeptide.…”
Section: Methodsmentioning
confidence: 99%
“…Hydroxyapatite (Ca 10 (PO 4 ) 6 (OH) 2 ; HAp) has been widely applied as a biomaterial for the substitution of human bone tissues because of its excellent biocompatibility and bioactivity, serving as an alternative to natural bone grafts [1,2]. The inorganic part of human bone and tooth has chemical and structural similarities to Ca-deficient hydroxyapatite, whereas the morphology of HAp can be significantly different in biological tissues, such as plate-like HAp crystals in bone and needle-like hexagonal prisms in enamel [3].…”
Section: Introductionmentioning
confidence: 99%
“…Synthetic HAP (CalO(P04MOH)2) is used mainly in hard tissue replacement applications since it is capable of undergoing bonding osteogenesis and is chemically stable in vivo for long periods of time [14], [15]. In order to prepare fine HAP powders, many chemical processing routes have been employed, including hydrothermal reactions, sol-gel synthesis, pyrolysis of aerosols and micro-emulsion [1], biomimetic process [2], and chemical precipitation [3], which is the most used alternative. Desired characteristics of synthesized hydroxyapatite are fine and uniform particle size, in the nanometre range, phase homogeneity and minimized degree of particle agglomeration.…”
Section: Introductionmentioning
confidence: 99%