Long-term Impact of Vascular Surgery Stress On Frail Older Patients

Gilbertson, Ellen; Bailey, Travis R.; Kraiss, Larry W.; Griffin, Claire L.; Smith, Brigitte K.; Sarfati, Mark R.; Beckstrom, Julie; Brooke, Benjamin S.

doi:10.1016/j.avsg.2020.01.062

Cited by 2 publications

(1 citation statement)

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“… 15 This implies that frail patients have a limited ability to cope with and recover from surgery, and are vulnerable to adverse outcomes. 16 For example, frail patients decrease in responses to hypoxia and hypercapnia, hypovolemia, and hypoxia; thus, they are more likely to have respiratory and circulatory failure intra- and postoperation. 17 …”

Section: Introductionmentioning

confidence: 99%

Frailty and Adverse Outcomes Among Older Patients Undergoing Gastroenterological Surgery in Vietnam

Nguyen

Pham

2021

JMDH

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Purpose With the ageing population, more older adults undergo surgery, and frailty increases the risk of postoperative complications in older patients. This study aimed to determine the association between frailty and 30-day adverse outcomes in older patients undergoing gastroenterological surgery in Vietnam. Patients and Methods A prospective cohort study was conducted in the Gastroenterology Department of the University Medical Center in Ho Chi Minh City. Frailty was determined using Fried’s criteria. Adverse outcomes within 30 days of gastroenterological surgery were recorded, including postoperative infections, acute respiratory failure, acute kidney injury, and death. Univariate and multivariate logistic analyses were performed to determine the association between frailty and 30-day postoperative adverse outcomes using Stata 14.0. Results Data of 302 elective surgical participants were collected (mean age: 69.8± 8.1 years, 53.3% female), and the prevalence of frailty was 18.5%. Frailty was an independent risk factor for 30-day adverse outcomes (odds ratio=6.56, 95% confidence interval, 2.77–15.53, p <0.001), which included postoperative infections, acute respiratory failure, acute kidney injury, and death. Frail participants had a significantly higher risk of postoperative infections (odds ratio=8.21, 95% confidence interval, 3.28–20.54, p <0.001), and exhaustion was strongly associated with postoperative adverse outcomes. Conclusion Frailty was a predictor of 30-day adverse outcomes in older patients undergoing gastroenterological surgery. Therefore, preoperative frailty should be screened in older patients, and frailty-associated risks should be considered during the decision-making process by physicians, patients, and their families.

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Section: Introductionmentioning

confidence: 99%