Long‐term non‐invasive positive airway pressure ventilation in infants

Abstract

NIV can be successfully and safely used in infants with prolonged life-threatening ventilatory failure, potentially avoiding intubation and tracheotomy.

A comparison of invasive and noninvasive ventilation in children less than 1 year of age: A long‐term follow‐up study

“…To the best of our knowledge, we are reporting on the largest cohort of children initiated on NiPPV at less than 1 year of age. Similar to the Markstrom and Bach studies, we found that NiPPV was effective; there was a significant improvement in PaCO 2 levels in all patients after the initiation of NiPPV . No deaths were attributable to equipment failure in our cohort which is another significant finding.…”

“…Similar to the Markstrom and Bach studies, we found that NiPPV was effective; there was a significant improvement in PaCO 2 levels in all patients after the initiation of NiPPV. 21,22 No deaths were attributable to equipment failure in our cohort which is another significant finding.…”

“…To our knowledge, Markstrom's case series is the only report to date which has described the outcomes of an infant cohort. 21 NiPPV was shown to effectively reduce the carbon dioxide levels in all infants. 21 Our aim was to report on the long-term survival of children initiated on NiPPV before the age of one to assess the safety and efficacy of NiPPV as compared to a comparator cohort of invasively ventilated children, the current gold standard for children less than 1 year of age.…”

“…Therefore, an understanding of the clinical outcomes of “off label noninvasive ventilation” in young children is essential to facilitate clinical decision making with families. To our knowledge, Markstrom's case series is the only report to date which has described the outcomes of an infant cohort . NiPPV was shown to effectively reduce the carbon dioxide levels in all infants …”

“…To our knowledge, Markstrom's case series is the only report to date which has described the outcomes of an infant cohort . NiPPV was shown to effectively reduce the carbon dioxide levels in all infants …”