Long-term observation of patients with MCI due to Lewy body who underwent intervention by prosthetic treatment

Inoue, Makoto; Manabe, Yuta; Isshiki, Yukari; Nagashima, Shintaro; Honma, Yuta; Kimoto, Katsuhiko

doi:10.2186/ajps.13.325

Cited by 2 publications

(4 citation statements)

References 3 publications

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“…We have previously reported that denture treatment leads to maintenance or temporary improvement of cognitive function in patients with MCI due to neurodegenerative diseases. In our clinical experience, this association is more common in DLB than in ATD patients 22 . However, the relationships between each causative disease of neurodegenerative dementia and the oral environment are unknown.…”

Section: Introductionmentioning

confidence: 82%

“…We hypothesise that the different causative neurodegenerative dementia diseases may allow for the differences in the association between oral function (masticatory performance) and frontal lobe function (e.g., cognition and attention). First, cognitive function may be maintained and temporarily recovered in patients with MCI receiving new dentures, which help restore masticatory performance; this outcome is more likely in patients with DLB than in those with ATD 22 . Second, the prefrontal cortex (PFC), which includes Brodmann areas 8 (part), 9–11, and 44–47, is the centre of working memory.…”

Section: Discussionmentioning

confidence: 99%

“…First, cognitive function may be maintained and temporarily recovered in patients with MCI receiving new dentures, which help restore masticatory performance; this outcome is more likely in patients with DLB than in those with ATD. 22 Second, the prefrontal cortex (PFC), which includes Brodmann areas 8 (part), 9-11, and 44-47, is the centre of working memory. However, DLB is characterised by reduced arousal due to the degenerative loss of nuclei, which control arousal, resulting in a marked reduction in working memory.…”

Section: Discussionmentioning

confidence: 99%

“…In our clinical experience, this association is more common in DLB than in ATD patients. 22 However, the relationships between each causative disease of neurodegenerative dementia and the oral environment are unknown. This study aimed to investigate the association between the oral environment and cerebral blood flow in patients with MCI and dementia due to ATD and DLB, and to determine the differences in the oral environment according to the underlying neurodegenerative disease type.…”

Section: Introductionmentioning

confidence: 99%

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Oral environment and cerebral blood flow in patients with neurodegenerative dementia: comparison of Alzheimer type dementia and dementia with Lewy bodies

et al. 2022

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Background: The number of patients with dementia is increasing worldwide. Modifying risk factors may significantly reduce the prevalence and cost of dementia. The number of remaining teeth, occlusal force, denture use, and periodontal disease status are associated with the risk of developing dementia. The oral environment may be a risk factor for dementia. This study aimed to investigate the association between the oral environment and cerebral blood flow in patients with mild cognitive impairment and dementia (either Alzheimer type dementia (ATD) or dementia with Lewy bodies (DLB)). We aimed to identify differences in the oral environment according to the underlying neurodegenerative disease. Methods: The participants were 25 patients with ATD and 25 patients with DLB who visited the

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Section: Introductionmentioning

confidence: 82%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Oral environment and cerebral blood flow in patients with neurodegenerative dementia: comparison of Alzheimer type dementia and dementia with Lewy bodies

et al. 2022

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Influences of Horticultural Therapy and Functional Recovery Training at a Day-Care Center for the Elderly and Text Mining of Care Records by AI

Koura,

Matsutani,

Nagao

et al. 2024

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Background: In Japan, due to the COVID-19 pandemic, various behavioral restrictions were implemented from March 2020, resulting in an increased number of elderly people with reduced participation in care and rehabilitation. As a result, the decline in motor and cognitive functions became more pronounced. Purpose: The study examined how activities combining passive horticultural therapy, which is always introduced, with active functional recovery training, which is used in the functional recovery training of patients with hemiplegia, influence the behavior of elder people using the facility. Methods: 36 elder people with care need 1 or 2 who regularly used the day-care facilities after the pandemic ended and who agreed to participate in the study was included. The assessment data were every three months from December 2021 to December 2023 after the COVID-19 pandemic, the MMSE and Moca-J, TMIG-Index, and GDS15. AI-based text mining was used to compare changes in visit reports before and after the introduction of the Posture Chart and Red Code, and the relationship between the language used. Results: The results of MMSE and Moca-J were both significantly higher in Group B and C than in Group A. TIMG assessment, was significantly higher in Group B and C than in Group A, and Group C was significantly higher than Group B. The GDS, an assessment of depression in old age, tended to be significantly higher in Group A than in Groups B and C. In the "Co-Occurrence Network Analysis" shown after the introduction of the latest functional recovery training equipment such as the Red Cord, its results showed a high association between the words Bathing and CARE and words such as POSTURE, Red-Code,

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Long-term observation of patients with MCI due to Lewy body who underwent intervention by prosthetic treatment

Cited by 2 publications

References 3 publications

Oral environment and cerebral blood flow in patients with neurodegenerative dementia: comparison of Alzheimer type dementia and dementia with Lewy bodies

Oral environment and cerebral blood flow in patients with neurodegenerative dementia: comparison of Alzheimer type dementia and dementia with Lewy bodies

Influences of Horticultural Therapy and Functional Recovery Training at a Day-Care Center for the Elderly and Text Mining of Care Records by AI

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