Long-Term Oncologic Outcomes After Laparoscopic Versus Open Resection for Colorectal Liver Metastases

Abstract

My special appreciation goes to a talented surgeon, my colleague and friend Dr. Åsmund Fretland, who has been a remarkable co-supervisor to me. Your research and surgical skills, positiveness and the ability to solve problems quickly have always impressed me. Thank you for letting me to take over your work in the OSLO-COMET trial and for introducing me to all the details. It is always my great pleasure to draft articles together with you, be your assistant at liver surgery and attend conferences together with you. My classmate, colleague and friend Dr. Mushegh Sahakyan deserves my deepest gratitude. You are a role model for me as a young talented and hard-working researcher. I have learned a lot from our discussions about surgical procedures, article drafting, methodologies and statistics in research. I am very glad that you are back to Norway and our research group. I look forward to continuing our fruitful cooperation and Armenian barbeques together. I would like to thank Prof. Erik Fosse for the opportunity to work at the Intervention Centre, where you have created an outstanding multi-speciality research team. Communication with multidisciplinary research teams and professionals at IVS have extended my horizons. It was my pleasure to work alongside Marianne Berg, Linda Engvik, nurses and radiology team.

Evolution of laparoscopic liver surgery: 20-year experience of a Norwegian high-volume referral center

“…Currently, seven surgeons independently perform laparoscopic liver resections, with different levels of expertise, The growing experience of our team, the results of our internal qualitative analyses and the worldwide interest in laparoscopic liver surgery inspired a prospective randomized controlled trial [8,9,[16][17][18]. The OSLO-COMET trial demonstrated the advantages of LLR in patients with CRLM [10,[19][20][21][22].…”

Pan-European survey on the implementation of robotic and laparoscopic minimally invasive liver surgery

“…The COMET randomized trial compared MILS versus open liver surgery for colorectal liver metastases and demonstrated lower complication rates, faster recovery, cost effectiveness and better quality of life in the MILS group as compared to the open group. 13,34,35 Similarly, the LapOpHuva randomized trial assessed short-term outcomes for MILS versus open liver surgery in patients with colorectal liver metastases and showed a significantly shorter hospital stay after MILS as compared to the open aproach. 5 The INSTALL-2 survey found that most 'difficult' laparoscopic MILS procedures reached the 'assessment' phase (IDEAL stage 3) in centers performing ˃100 laparoscopic MILS anually.…”

Simultaneous Resection of Primary Colorectal Cancer and Synchronous Liver Metastases: Contemporary Practice, Evidence and Knowledge Gaps

“…There is reason to believe that minimally invasive techniques for both the liver and the colorectal part of the procedure are associated with beneficial short-term outcomes [31,32]. As for laparoscopic liver surgery, there is evidence to support equal oncological outcomes for laparoscopic and open colon surgery [33,34]. The colorectal surgery should be performed by a trained colorectal surgeon and the liver surgery by a trained hepatobiliary surgeon.…”