Long-term Oncologic Outcomes of Robotic-assisted Radical Prostatectomy by a Single Surgeon

Hung, Sheng-Chun; Yang, Chen-Kuang; Cheng, Chen-Li; Ou, Yen‐Chuan

doi:10.21873/anticanres.11803

Cited by 2 publications

(1 citation statement)

References 21 publications

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“…Классификация риска по шкале D'Amico была эффективной для прогнозирования БХР у пациентов, перенесших РАРП. Послеоперационные факторы риска, такие как метастазы в лимфатических узлах, индекс Глисона и самый низкий уровень ПСА <0,003 нг / мл, были независимыми предикторами БХР [29].…”

Section: Introductionunclassified

Long-term oncological and functional results of robot-assisted radical prostatectomy

et al. 2021

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Prostate cancer (РСа), being one of the leading causes of cancer mortality in men in Russia and in a number of other countries of the world, remains an urgent problem for modern oncourology, and the choice of surgical method is an important task for a surgeon. Such a pronounced interest in robot-assisted radical prostatectomy (RARP) in patients is driven by good tolerance and effectiveness of these surgical interventions, despite the fact that radical prostatectomy is considered to be the "gold standard" for treatment of patients with clinically localized РСа with regard to European Association of Urology data. The long-term oncological and functional results and the quality of life of patients after RARP deserve close attention and thorough study. According to the data presented in this article, it is obvious that RARP is the preferred method for surgical treatment of РСа, since oncological and functional results in the long-term follow-up are comparable to the results after radical prostatectomy, and according to some authors, these results are superior to the results of radical prostatectomy. The results of the study will allow to continue further introduction of RARP into clinical practice and its popularization as a method of surgical treatment of patients with localized PCa, which will reduce the length of hospital stay of patients, accelerate their medical and social rehabilitation, and improve the quality of medical care.The amount of data on the study of distant oncological and functional results of RARP as well as its superiority over other treatment methods is limited in medical literature, which prompted us to conduct our own research. Currently the urological clinic of the A.I. Evdokimov Moscow State University of Medicine and Dentistry continues work aimed at studying the longterm results of RARP in the first patients in Russia.

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Section: Introductionunclassified

Long-term oncological and functional results of robot-assisted radical prostatectomy

et al. 2021

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Diagnostic and prognostic factors in patients with prostate cancer: a systematic review

et al. 2022

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ObjectivesAs part of the PIONEER Consortium objectives, we have explored which diagnostic and prognostic factors (DPFs) are available in relation to our previously defined clinician and patient-reported outcomes for prostate cancer (PCa).DesignWe performed a systematic review to identify validated and non-validated studies.Data sourcesMEDLINE, Embase and the Cochrane Library were searched on 21 January 2020.Eligibility criteriaOnly quantitative studies were included. Single studies with fewer than 50 participants, published before 2014 and looking at outcomes which are not prioritised in the PIONEER core outcome set were excluded.Data extraction and synthesisAfter initial screening, we extracted data following the Checklist for Critical Appraisal and Data Extraction for Systematic Reviews of prognostic factor studies (CHARMS-PF) criteria and discussed the identified factors with a multidisciplinary expert group. The quality of the included papers was scored for applicability and risk of bias using validated tools such as PROBAST, Quality in Prognostic Studies and Quality Assessment of Diagnostic Accuracy Studies 2.ResultsThe search identified 6604 studies, from which 489 DPFs were included. Sixty-four of those were internally or externally validated. However, only three studies on diagnostic and seven studies on prognostic factors had a low risk of bias and a low risk concerning applicability.ConclusionMost of the DPFs identified require additional evaluation and validation in properly designed studies before they can be recommended for use in clinical practice. The PIONEER online search tool for DPFs for PCa will enable researchers to understand the quality of the current research and help them design future studies.Ethics and disseminationThere are no ethical implications.

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Long-term Oncologic Outcomes of Robotic-assisted Radical Prostatectomy by a Single Surgeon

Abstract: D'Amico risk classification was effective at predicting biochemical recurrence in patients receiving RARP. Furthermore, postoperative risk factors such as metastatic lymph node, pathology Gleason score, and nadir PSA <0.003 ng/ml were independent predictors of biochemical recurrence.

Cited by 2 publications

References 21 publications

Long-term oncological and functional results of robot-assisted radical prostatectomy

Long-term oncological and functional results of robot-assisted radical prostatectomy

Diagnostic and prognostic factors in patients with prostate cancer: a systematic review

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