Long-term oral antibiotics for acne: Is laboratory monitoring necessary?

Driscoll, Marcia S.; Rothe, Marti Jill; Abrahamian, Lori M.; Grant‐Kels, Jane M.

doi:10.1016/0190-9622(93)70080-d

Cited by 27 publications

(8 citation statements)

References 31 publications

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“…Tetracyclines are well known for their use in treating bacterial infections, and their adverse effects have been well documented [ 8 , 9 ]. At the usual doses prescribed for malaria chemoprophylaxis, the published data are limited, and the reported adverse events vary widely.…”

Section: Side Effects and Warnings Against Doxycyclinementioning

confidence: 99%

Tetracyclines in malaria

Gaillard

Madamet

Pradines

2015

Malar J

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Malaria, a parasite vector-borne disease, is one of the greatest health threats in tropical regions, despite the availability of malaria chemoprophylaxis. The emergence and rapid extension of Plasmodium falciparum resistance to various anti-malarial drugs has gradually limited the number of potential malaria therapeutics available to clinicians. In this context, doxycycline, a synthetically derived tetracycline, constitutes an interesting alternative for malaria treatment and prophylaxis. Doxycycline is a slow-acting blood schizontocidal agent that is highly effective at preventing malaria. In areas with chloroquine and multidrug-resistant P. falciparum parasites, doxycycline has already been successfully used in combination with quinine to treat malaria, and it has been proven to be effective and well-tolerated. Although not recommended for pregnant women and children younger than 8 years of age, severe adverse effects are rarely reported. In addition, resistance to doxycycline is rarely described. Prophylactic and clinical failures of doxycycline have been associated with both inadequate doses and poor patient compliance. The effects of tetracyclines on parasites are not completely understood. A better comprehension of the mechanisms underlying drug resistance would facilitate the identification of molecular markers of resistance to predict and survey the emergence of resistance.

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Section: Side Effects and Warnings Against Doxycyclinementioning

confidence: 99%

Tetracyclines in malaria

Gaillard

Madamet

Pradines

2015

Malar J

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“…In contrast, Driscoll et al (1) do not recommend routine laboratory monitoring in young patients treated with minocycline for acne, as the serious adverse effects of minocycline do not have an asymptomatic period during which early detection can lead to prevention or amelioration of the reactions. These reactions are idiosyncratic and are best detected after the development of symptoms.…”

Section: Discussionmentioning

confidence: 99%

“…Acne vulgaris is a chronic inflammatory skin condition common in adolescence, characterized by skin eruptions on the face, chest, and back. Systemic antibiotics have been used to treat acne vulgaris for approximately 40 years (1). Minocycline is the most widely prescribed systemic antibiotic for acne, largely because it is given once or twice a day and does not seem to induce resistance (2).…”

mentioning

confidence: 99%

Complications of Minocycline Therapy for Acne Vulgaris: Case Reports and Review of the Literature

Somech

Arav‐Boger

Assia

et al. 1999

Pediatric Dermatology

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“…). Affected teeth mostly display chronological, discolored banding which can be related to the period of ingestion . A number of prenatal and neonatal discolorations of the enamel are due to hemolytic anemias, for instance caused by Rhesus incompatibility , or to inborn errors of metabolism such as congenital oxalosis or ochronosis .…”

Section: Diagnosis and Differential Diagnosis Of Defective Dentinogenmentioning

confidence: 99%

Dentin disorders: anomalies of dentin formation and structure

Coster¹

2009

Endodontic Topics

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Dentin defects represent a cluster of relatively rare heritable disorders affecting the formation and mineralization of dentin. Major clinical features include loss of enamel with extreme wear of exposed dentin, opalescent tooth discoloration, short roots with pulpal calcification and increased tooth mobility, and frequent periapical radiolucencies. Historically, these inherited conditions have been classified by Shields et al. (1) as either dentinogenesis imperfecta (DGI) types I, II and III, or dentin dysplasia (DD) types I and II. DGI type I is now universally designated as osteogenesis imperfecta with dentinogenesis imperfecta (OI/DGI) and is caused by type I collagen mutations. Among the genes expressing the non‐collagenous proteins in dentin, only the DSPP gene has been implicated in the etiology of DD type II and all DGI types, suggesting that heritable dentin defects can be viewed as a continuum rather than as distinct disease entities. Dental treatment strategies should aim to preserve the affected dentitions by protecting teeth from wear, restoring them to compliance with the specific structural characteristics of the defective dentin, and anticipating early tooth loss. Endodontic treatment of the affected teeth is very challenging because of the peculiar pulp morphology and most often has poor prognosis. If conventional therapy is not an option, periapical curettage and retrograde filling is a possible alternative, except in the case of teeth with short roots.

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Long-term oral antibiotics for acne: Is laboratory monitoring necessary?

Cited by 27 publications

References 31 publications

Tetracyclines in malaria

Tetracyclines in malaria

Complications of Minocycline Therapy for Acne Vulgaris: Case Reports and Review of the Literature

Dentin disorders: anomalies of dentin formation and structure

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