Long-term outcome after the mustard repair for simple transposition of the great arteries

Wilson, Nigel; Clarkson, P. M.; Barratt‐Boyes, B. G.; Calder, A. Louise; Whitlock, R. M. L.; Easthope, R. N.; Neutze, John M.

doi:10.1016/s0735-1097(98)00309-x

Cited by 200 publications

(111 citation statements)

References 23 publications

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“…However, even if some authors 19,20 found a progressive decrease of RV function with time, the inevitability of decline of the right ventricle in follow-up remains unproven. Indeed, in some longitudinal studies, 15,16 RV function remained stable during the follow-up period.…”

Section: Right Ventricular Dysfunctionmentioning

confidence: 95%

“…So far, our experience is too limited to draw conclusions. Some authors 9,13,15 have also demonstrated that during exercise stress testing there is a significantly reduced endurance time and a reduced maximal achieved heart rate.…”

Section: Right Ventricular Dysfunctionmentioning

confidence: 99%

“…18 In our series the incidence of late sudden death was 2.9%, which is in agreement with the range of 2-8% reported in the literature. 5,6,[10][11][12][13][14][15][16] …”

Section: Sudden Deathmentioning

confidence: 99%

“…Some authors 15 have demonstrated a better functional status of the right ventricle in patients operated on within 6 to 9 months of age compared with those operated on later. They speculated that cyanosis may cause impairment to RV contractility preservation.…”

Section: Right Ventricular Dysfunctionmentioning

confidence: 99%

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Long‐term outcome after senning operation for transposition of the great arteries

Agnetti

Coppola

Cavalli

et al. 2004

Clinical Cardiology

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SummaryBackground: The Senning operation for transposition of the great arteries (TGA) was first introduced by Senning in 1959 and was revived by Quaegebeur et al. in the late 1970s, thus becoming the intervention of choice for the correction of TGA in many centers.Hypothesis: The purpose of this study was to evaluate the long-term follow-up of a group of patients undergoing surgery with the Senning procedure for TGA.Methods: From November 1978 to November 1987, 73 consecutive patients underwent the Senning operation. The 70 survivors had an average follow-up of 19 years (16-25 years).Results: (1) Cardiac rhythm: with time there was a progressive decrease in stable sinus rhythm (60% after 20 years) and a progressive increase of supraventricular tachyarrhythmias requiring therapy (10% after 20 years). (2) Right ventricular function: 20% of the patients had reduced ejection fraction. (3) Late mortality: in the last 12 years of follow-up years there were two sudden deaths (2.8%). (4) Functional status: 80% of patients were in NYHA class I, 17% in class II, and 3% in class III.Conclusions: Our results confirm that the patients who undergo the Senning procedure have a progressive loss of sinus rhythm, an increase in active arrhythmias, and other important adverse outcomes such as late sudden death and a decrease in right ventricular function; however, most patients (93% in our series) are alive and in good functional status.

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Section: Right Ventricular Dysfunctionmentioning

confidence: 95%

Section: Right Ventricular Dysfunctionmentioning

confidence: 99%

“…18 In our series the incidence of late sudden death was 2.9%, which is in agreement with the range of 2-8% reported in the literature. 5,6,[10][11][12][13][14][15][16] …”

Section: Sudden Deathmentioning

confidence: 99%

Section: Right Ventricular Dysfunctionmentioning

confidence: 99%

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Long‐term outcome after senning operation for transposition of the great arteries

Agnetti

Coppola

Cavalli

et al. 2004

Clinical Cardiology

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“…19 Late attrition from RV failure and arrhythmias is an ongoing issue, however, that warrants continued follow-up. 13 The long-term prognosis must be guarded, and in later decades it is possible that many will require cardiac transplantation.…”

Section: Systemic Ventricular Dysfunction and Tricuspid Regurgitationmentioning

confidence: 99%

Transposition of the Great Arteries

2006

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Abstract-Many patients with ventriculoarterial discordance have survived to adulthood. Those with complete transposition of the great arteries have often had an atrial switch procedure (Mustard or Senning operation) performed, which leaves the morphological right ventricle (RV) supporting the systemic circulation. RV failure and tricuspid regurgitation are common. Some patients may ultimately require cardiac transplantation. Sinus node dysfunction is increasingly common with longer follow-up, and some patients need pacemaker implantation. Atrial arrhythmias are frequent, and atrial flutter may be a marker for sudden death. Patients with an arterial switch procedure are also surviving to adulthood. Long-term problems include coronary stenoses, distortion of the pulmonary arteries, dilatation of the neoaortic root, and aortic regurgitation. Patients with congenitally corrected transposition have both atrioventricular and ventriculoarterial discordance and therefore also have a morphological RV and delicate tricuspid valve in the systemic circulation. Associated defects, such as abnormalities of the tricuspid valve, ventricular septal defect, and pulmonary stenosis, occur in the majority of patients. Heart block occurs with increasing age. Atrial arrhythmias occur frequently, and their occurrence should prompt a search for a hemodynamic problem. Progressive tricuspid regurgitation occurs with age and is associated with deterioration of RV function. Surgical treatment should be considered at the earliest sign of RV dilatation or dysfunction. All patients should be seen periodically in a center where expertise in the clinical evaluation, imaging, and hemodynamic assessment of adult congenital heart disease is available.

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Caliber of Quality-of-Life Assessments in Congenital Heart Disease

Moons¹,

Deyk²,

Budts³

et al. 2004

Arch Pediatr Adolesc Med

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A poor conceptual and methodological basis for quality of life implies that many results from quality-of-life studies performed in patients with congenital heart disease contribute little to the scientific knowledge base of quality of life in this patient population. Future quality-of-life studies need to invest in a rigorous conceptualization, an adequate operational definition, and a sound measurement of quality of life.

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Long-term outcome after the mustard repair for simple transposition of the great arteries

Cited by 200 publications

References 23 publications

Long‐term outcome after senning operation for transposition of the great arteries

Long‐term outcome after senning operation for transposition of the great arteries

Transposition of the Great Arteries

Caliber of Quality-of-Life Assessments in Congenital Heart Disease

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