Long-term outcome of non-surgical treatment for pancreatolithiasis: Factors influencing recurrence and exocrine pancreatic function

Yamamoto, Satoshi; Inui, Kentaro; Yoshino, Junji; Miyoshi, Hideaki; Kobayashi, Takashi

doi:10.2958/suizo.26.699

Cited by 3 publications

(7 citation statements)

References 9 publications

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“…Yamamoto et al reported that the recurrence rate was significantly higher Intern Med 61: 3633-3639, 2022 DOI: 10.2169/internalmedicine.9038-21 in non-elderly patients (<65 years old) than in elderly patients (! 65 years old) (8). Similarly, in the present study, age <63 years old was one of the factors identified as being associated with retreatment after ESWL.…”

Section: Discussionsupporting

confidence: 81%

“…Previous studies have reported that there are some risk factors for stone recurrence following ESWL. Yamamoto et al reported that the recurrence rate was significantly higher in non-elderly patients (＜65 years old) than in elderly patients (≥65 years old) ( 8 ). Similarly, in the present study, age ＜63 years old was one of the factors identified as being associated with retreatment after ESWL.…”

Section: Discussionmentioning

confidence: 99%

“…Therefore, non-elderly patients need to be carefully monitored after ESWL. Regarding the etiology of CP, the stone recurrence rate of alcohol-induced CP is known to be higher than that of non-alcohol-induced CP ( 8 ). In patients with alcohol-induced CP, continued alcohol abuse is a risk factor for stone recurrence following ESWL ( 7 ).…”

Section: Discussionmentioning

confidence: 99%

“…ESWL is reported to be less invasive and with higher efficacy and lower complication rates than surgery ( 5 , 6 ). However, the high recurrence rate of pancreatolithiasis (up to 40%) after ESWL remains an important clinical problem ( 7 , 8 ). Little is known about the predictive factors of recurrence after ESWL.…”

Section: Introductionmentioning

confidence: 99%

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The Visceral-to-subcutaneous Adipose Tissue Area Ratio Is Associated with Retreatment in Chronic Pancreatitis Patients with Pancreatolithiasis after Extracorporeal Shock Wave Lithotripsy

et al. 2022

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Objective Extracorporeal shock wave lithotripsy (ESWL) has been used to treat pancreatolithiasis in patients with chronic pancreatitis (CP), but the high recurrence rate remains challenging. We therefore evaluated the association between body composition parameters and the prediction of retreatment after ESWL. Methods This study retrospectively evaluated 42 patients with CP who had been treated with ESWL between 2008 and 2019 in a single center. Body composition parameters were measured on pretreatment computed tomography images. Patients who underwent repeat ESWL were classified as the retreatment group. Results There were 13 (31.0%) and 29 (69.0%) patients in the retreatment and non-retreatment groups, respectively. The visceral-to-subcutaneous adipose tissue area ratio (VSR) of the retreatment group was significantly lower than that of the non-retreatment group (p=0.016). When divided by the median VSR, 10 of the 20 patients with a VSR of <0.85 underwent retreatment, whereas 3 of the 22 patients with a VSR of ! 0.85 underwent retreatment (p=0.019). According to a multivariate analysis, the VSR (p=0.010) and age (p=0.037) were independent factors associated with retreatment after ESWL. Conclusion This study showed that the VSR can predict the retreatment of patients with CP after ESWL.

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Section: Discussionsupporting

confidence: 81%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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The Visceral-to-subcutaneous Adipose Tissue Area Ratio Is Associated with Retreatment in Chronic Pancreatitis Patients with Pancreatolithiasis after Extracorporeal Shock Wave Lithotripsy

et al. 2022

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“…17,18 Recently, Delhaye 19 reported that ESWL can be used as a first-line treatment when obstructive ductal stones cause 22 reported that endoscopic management and ESWL does not prevent or postpone the development of glandular insufficiency. Yamamoto et al 23 reported that exocrine pancreatic function (N-benzoil-L-tyrosil-para-amino benzoic acid test) was relatively preserved over the long term after treatment of pancreatolithiasis with ESWL.…”

Section: Treatment Of Chronic Pancreatitismentioning

confidence: 99%

New developments in diagnosis and non‐surgical treatment of chronic pancreatitis

Inui

Yoshino

Miyoshi

et al. 2013

J of Gastro and Hepatol

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Chronic pancreatitis is progressive and irreversible, leading to digestive and absorptive disorders by destruction of the exocrine pancreas and to diabetes mellitus by destruction of the endocrine pancreas. When complications such as pancreatolithiasis and pseudocyst occur, elevated pancreatic ductal pressure exacerbates pain and induces other complications, worsening the patient's general condition. Combined treatment with extracorporeal shock-wave lithotripsy and endoscopic lithotripsy is a useful, minimally invasive, firstline treatment approach that can preserve pancreatic exocrine function. Pancreatic duct stenosis elevates intraductal pressure and favor both pancreatolithiasis and pseudocyst formation, making effective treatment vitally important. Endoscopic treatment of benign pancreatic duct stenosis stenting frequently decreases pain in chronic pancreatitis. Importantly, stenosis of the main pancreatic duct increases risk of stone recurrence after treatment of pancreatolithiasis. Recently, good results were reported in treating pancreatic duct stricture with a fully covered self-expandable metallic stent, which shows promise for preventing stone recurrence after lithotripsy in patients with pancreatic stricture. Chronic pancreatitis has many complications including pancreatic carcinoma, pancreatic atrophy, and loss of exocrine and endocrine function, as well as frequent recurrence of stones after treatment of pancreatolithiasis. As early treatment of chronic pancreatitis is essential, the new concept of early chronic pancreatitis, including characteristics findings in endoscopic ultrasonograms, is presented.

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Clinical effectiveness of ESWL/endoscopic therapy for painful chronic pancreatitis

弘隆

香月

格

et al. 2015

Journal of the Japan Pancreas Society

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Long-term outcome of non-surgical treatment for pancreatolithiasis: Factors influencing recurrence and exocrine pancreatic function

Cited by 3 publications

References 9 publications

The Visceral-to-subcutaneous Adipose Tissue Area Ratio Is Associated with Retreatment in Chronic Pancreatitis Patients with Pancreatolithiasis after Extracorporeal Shock Wave Lithotripsy

The Visceral-to-subcutaneous Adipose Tissue Area Ratio Is Associated with Retreatment in Chronic Pancreatitis Patients with Pancreatolithiasis after Extracorporeal Shock Wave Lithotripsy

New developments in diagnosis and non‐surgical treatment of chronic pancreatitis

Clinical effectiveness of ESWL/endoscopic therapy for painful chronic pancreatitis

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