Long-Term Outcome of Noninvasive Positive Pressure Ventilation for Obesity Hypoventilation Syndrome

Priou, Pascaline; Hamel, Jean‐François; Person, Christine; Meslier, Nicole; Racineux, Jean-Louis; Urban, T.; Gagnadoux, Frédéric

doi:10.1378/chest.09-2472

Cited by 178 publications

(172 citation statements)

References 28 publications

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“…7,11,12 According to our results, prioritizing patient preference for prescription would increase ONM use to almost 50%, which represents a substantial change in the use profile of this interface.…”

Section: Discussionmentioning

confidence: 66%

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Nasal Versus Oronasal Mask in Home Mechanical Ventilation: The Preference of Patients as a Strategy for Choosing the Interface

et al. 2012

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INTRODUCTION:In home mechanical ventilation (HMV), the mask is a key factor for patient comfort and therapeutic adherence. There is no evidence on the best strategy for choosing the mask in HMV. OBJECTIVE: To explore patient preference when prescribing the mask for HMV treatment and assess its relationship with effectiveness. METHODS: A prospective study with repeated measures in stable patients receiving home nocturnal ventilation. Alternating oronasal mask (ONM) and nasal mask (NM) were tested in day and overnight sessions, with arterial blood gas measured and S pO 2 monitored. At the end of each evening session, patients rated interface comfort using a visual analog scale. At 3 months we evaluated adherence and effectiveness of the treatment. RE-SULTS: Twenty-nine subjects (mean ؎ SD age 65 ؎ 13 y, 44% male) completed the study. Initial functional values were P CO 2 57.4 ؎ 5.2 mm Hg and time with S pO 2 < 90% (T90) 81.5 ؎ 9.5%. Both ONM and NM significantly decreased P CO 2 and T90. Over a third (38%) of our subjects preferred ONM, while NM was deemed more comfortable in general. At 3 months, effectiveness and adherence showed no differences between those treated with NM or ONM. CONCLUSIONS: Patient choice is an effective criterion for selecting the interface in HMV treatment.

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Section: Discussionmentioning

confidence: 66%

“…Some authors use ONM when they detect problems in NM ventilation. 7 Our results suggest that a combination of effectiveness and patient preference from the outset may be a more appropriate strategy.…”

Section: Discussionmentioning

confidence: 77%

Nasal Versus Oronasal Mask in Home Mechanical Ventilation: The Preference of Patients as a Strategy for Choosing the Interface

et al. 2012

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“…[50,[74][75][76] Bi-level PAP therapy is beneficial in preventing obstructive events, improving expiratory flow limitation and also improves tidal volume by providing inspiratory pressure support. Bilevel therapy when used long term has been shown to improve blood gases, quality of life and ventilator responsiveness to CO 2 [50,70,[77][78][79][80][81]. Bi-level PAP therapy unloads inspiratory muscles and has been shown to reduce diaphragmatic effort by nearly 40% [34].…”

Section: Bi-level Papmentioning

confidence: 99%

“…On KaplanMeier analysis, 1-, 2-, 3-, and 5-year survival probabilities were 97.5%, 93%, 88.3%, and 77.3%, respectively with no significant difference noted between the two groups. Analysis of possible prognostic factors like heart disease, baseline PCO 2 > 50 mmHg, baseline serum bicarbonate >30 meq/dL and hypoxia showed that supplemental oxygen was the only independent predictor of mortality [77].…”

Section: Long Term Effects Mortality and Prognosis Of Pap Therapymentioning

confidence: 99%

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Obesity Hypoventilation Syndrome

2010

IJPM

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Obesity hypoventilation syndrome is a respiratory consequence of morbid obesity that is characterized by alveolar hypoventilation during sleep and wakefulness. The disorder involves a complex interaction between impaired respiratory mechanics, ventilatory drive and sleepdisordered breathing. Early diagnosis and treatment is important, because delay in treatment is associated with significant mortality and morbidity. Available treatment options include noninvasive positive airway pressure (PAP) therapies and weight loss. There is limited long-term data regarding the effectiveness of such therapies. This review outlines the current concepts of clinical presentation, diagnostic and management strategies to help identify and treat patients with obesityhypoventilation syndromes.

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Non-invasive positive airway pressure therapy for obesity hypoventilation syndrome in adults

Chung

Garden

Marks

et al. 2018

Cochrane Database of Systematic Reviews

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Long-Term Outcome of Noninvasive Positive Pressure Ventilation for Obesity Hypoventilation Syndrome

Cited by 178 publications

References 28 publications

Nasal Versus Oronasal Mask in Home Mechanical Ventilation: The Preference of Patients as a Strategy for Choosing the Interface

Nasal Versus Oronasal Mask in Home Mechanical Ventilation: The Preference of Patients as a Strategy for Choosing the Interface

Obesity Hypoventilation Syndrome

Non-invasive positive airway pressure therapy for obesity hypoventilation syndrome in adults

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