Long-term outcome of surgically and medically treated patients with gastroesophageal reflux disease: A matched-pair follow-up study

Abstract

The study shows that in our area anti-reflux surgery is more effective in relieving reflux symptoms than medical care according to clinical practice.

The prevalence of sexual behavior disorders in patients with treated and untreated gastroesophageal reflux disease

“…Moreover, we found that 19.4 % of patients who had undergone the procedure were taking antireflux drugs occasionally. This percentage is similar to that previously reported [16]. We could not obtain a specific utility and incorporate these results into our model given the format of our study.…”

Airway symptoms and sleeping difficulties in operated and non-operated patients with gastroesophageal reflux disease

“…In 2002, we performed a 3-10 years follow-up study of patients with GERD treated with fundoplication, and matched non-operated controls that had been treated with anti-reflux medications, according to clinical practice in our region [18]. In contrast to the similar results of medical and surgical treatments that have been found in prospective controlled studies [19], we found that operated patients reported significantly less heartburn/acid regurgitation than their non-operated controls.…”

“…All patients were recruited because they were responders in a follow-up questionnaire study one-and-a-half years earlier, focusing on gastroenterological symptoms and health-related quality of life [18]. Indications for surgery were according to clinical practice in our two hospitals.…”

Gastroösophageale Refluxerkrankung

“…Bei der Fundoplikation wird durch Repositionierung des unteren Ösophagussphinkters im Abdomen und Anlegen einer vollständigen oder partiellen Manschette aus Fundusanteilen des Magens um den unteren Öso-phagus die Refluxbarriere verstärkt. In kontrollierten Studien waren die Langzeitergebnisse der laparoskopischen oder offenen Fundoplikation mit denen der medikamentösen Therapie vergleichbar [13,19], gingen aber mit einer erhöhten Mortalität und Morbidität einher. Komplikationen umfassen anhaltende Schluckbeschwerden und Blähungen.…”