Long-term outcome of transoral organ-preserving pharyngeal endoscopic resection for superficial pharyngeal cancer

Endoscopic laryngo-pharyngeal surgery for superficial laryngo-pharyngeal cancer

“…This has provided a breakthrough in diagnosis, and we have applied it to this issue to create a strategy for such early stage cancer because the conventional treatment strategy, including open surgery and chemoradiotherapy, seems to be overtreatment [4]. Transoral surgery is becoming popular as a minimally invasive treatment for laryngo-pharyngeal cancer, since Steiner et al reported an excellent local control rate while preserving swallowing and voice function [10][11][12].…”

“…Transoral surgery is becoming popular as a minimally invasive treatment for laryngo-pharyngeal cancer, since Steiner et al reported an excellent local control rate while preserving swallowing and voice function [10][11][12]. To date, several methods have been reported as a minimally invasive transoral surgical approach, such as transoral laser microsurgery (TLM), transoral robotic surgery (TORS) [13][14][15], transoral videolaryngoscopic surgery (TOVS) [16], and ESD [4,5], and the merits and demerits of each procedure are becoming evident. It has been reported that TLM for laryngo-pharyngeal cancer results in an excellent organ preservation rate [11,12].…”

“…A gastroenterologist resects the mucosa containing the lesion at the subepithelial level using a coagulator and forceps inserted through a flexible endoscope, and, if necessary, an otolaryngologist assists the procedure by retracting the mucosa with orally inserted forceps. ESD is safe and achieves a good local control rate for early laryngo-pharyngeal cancer [4,5]. However, ESD also has limitations, such as its technical difficulty because of the one-arm procedure through the endoscope and the relatively longer surgical time because of the one-handed operation.…”

“…We have previously reported that narrowband imaging (NBI) combined with magnifying endoscopy is useful in detecting early superficial laryngo-pharyngeal cancers, which are difficult to detect by standard endoscopy [1][2][3]. For such superficial lesions, we have reported endoscopic submucosal dissection (ESD) [4]. In this procedure, the cancerous lesion with safety margin is resected with minimal invasion using a knife needle inserted through a flexible gastrointestinal endoscope.…”

Narrow-band Imaging for the Head and Neck Region and the Upper Gastrointestinal Tract

“…The early detection of cancer in this region increases the possibility of minimally invasive surgery, including endoscopic mucosal resection and endoscopic submucosal dissection methods (19,20). The potential advantages to patients resulting from an early diagnosis, with the preservation of organ and tissue functions, are obvious.…”