Long-term outcomes in survivors of acute respiratory distress syndrome ventilated in supine or prone position

Chiumello, Davide; Taccone, Paolo; Berto, Virna; Marino, Antonella; Migliara, Giuseppe; Lazzerini, M.; Gattinoni, Luciano

doi:10.1007/s00134-011-2445-4

Cited by 34 publications

(38 citation statements)

References 50 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…To investigate the influence of rescue therapies on 1-y mortality, Chiumello et al 25 compared ARDS subjects ventilated in prone or supine position without finding any difference, although they reported an overall high mortality rate (60%). They could not establish whether this high rate was mainly due to respiratory function impairment or extrapulmonary complications.…”

Section: Long-term Mortalitymentioning

confidence: 99%

“…56 Chiumello et al 25 investigated a group of ARDS subjects managed with protective ventilation previously enrolled in a randomized multi-center trial to test the long-term outcomes of patients receiving prone compared with supine positioning. The mean extent of reticular pattern was Ͻ10 -15% of total lung volume 1 y after ARDS in both supine and prone groups, and there were also no differences in the amount of collapsed (8.1 Ϯ 3.1% vs 7.3 Ϯ 3.4%), poorly aerated (15.3 Ϯ 3.6% vs 17.1 Ϯ 4.9%), and well aerated (64.0 Ϯ 8.4% vs 70.2 Ϯ 8.4%) tissue between the 2 groups.…”

Section: Radiological Findingsmentioning

confidence: 99%

“…The distance increased quickly in the first year after ICU discharge from 49% to 66 -75% of predicted, and then this value remained nearly constant, at a value that was below the lower limit of normality. 21,25,34,38 Whether this inability to exercise is due to dyspnea or to muscle weakness is unknown; probably, it is multifactorial. In fact, no correlation was found in the literature between parenchymal abnormalities, detected with follow-up CT scan, respiratory symptoms, pulmonary function tests, and 6-min walk tests.…”

Section: Pulmonary Dysfunctionmentioning

confidence: 99%

See 2 more Smart Citations

What's Next After ARDS: Long-Term Outcomes

et al. 2016

Self Cite

View full text Add to dashboard Cite

SummaryARDS is a life-threatening organ failure due to several pulmonary and extrapulmonary injuries with an incidence between 5 and 60 cases/100,000 persons/y. Patients with ARDS have non-cardiogenic pulmonary edema and dyspnea often requiring invasive mechanical ventilation and intensive care admission. Although the short-term mortality rate has significantly decreased in the last decade, mainly due to the widespread application of lung-protective ventilation and better general support, long-term outcomes are still unsatisfactory. Besides simply evaluating the outcome at hospital discharge, several recent studies have assessed the health-related quality of life, neuropsychological disability, radiological findings, and pulmonary dysfunction up to 5 y. This paper reviews the literature regarding the long-term outcomes in patients with ARDS. Key words: ARDS; long-term outcomes; health-related quality of life; neuropsychological disability; pulmonary function; lung imaging. [Respir Care 2016;61(5):689 -699.

show abstract

Section: Long-term Mortalitymentioning

confidence: 99%

Section: Radiological Findingsmentioning

confidence: 99%

Section: Pulmonary Dysfunctionmentioning

confidence: 99%

See 1 more Smart Citation

What's Next After ARDS: Long-Term Outcomes

et al. 2016

Self Cite

View full text Add to dashboard Cite

show abstract

“…The findings reported by Needham and colleagues 4 were similar to a recent smaller European study where overall mortality in patients with ARDS at 12 months was 60%. 10 The study by Needham and colleagues 4 underscores the previous findings that LPV has not yet been applied systematically to patients with ARDS, even at centers with a high degree of experience with LPV. 11 Moreover, there is mounting evidence regarding the importance of limiting V T to prevent ARDS in at-risk patients, 12 as well as preventing both ARDS and non-pulmonary organ damage in patients without known risk factors.…”

Section: Tidal Volume and 2-year Mortality In Ardsmentioning

confidence: 92%

Respiratory Care Year in Review 2012: Invasive Mechanical Ventilation, Noninvasive Ventilation, and Cystic Fibrosis

2013

View full text Add to dashboard Cite

SummaryFor the busy clinician, educator, or manager, it is becoming an increasing challenge to filter the literature to what is relevant to one's practice and then update one's practice based on the current evidence. The purpose of this paper is to review the recent literature related to invasive mechanical ventilation, noninvasive ventilation, and cystic fibrosis. These topics were chosen and reviewed in a manner that is most likely to have interest to the readers of RESPIRATORY CARE.

show abstract

“…The full impact of ARDS extends beyond the fact of whether or not patients leave the hospital alive. Within the last few years, several studies have shown that long-term morbidity induced by ARDS is substantial, as patients may suffer from persistent physical constraints and weakness to new-onset neurocognitive disorders, such as depression and long-lasting cognitive impairment [2,3,10,11]. Among the major comorbidities, malignant disease has a major physical and psychological burden in itself [12].…”

mentioning

confidence: 99%