Long-term outcomes of surgery for Peyronie’s disease: focus on patient satisfaction

Гамидов, С. И.; Shatylko, T. V.; Гасанов, Н. Г.; Scherbakov, D. V.; Li, Konstantin; Сухих, Г. Т.

doi:10.1038/s41443-020-0297-6

Cited by 7 publications

(6 citation statements)

References 21 publications

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“…Patients showed good overall Quality of Life and Sexuality with Penile Prosthesis scores at 1-year follow-up for functional (22/25), personal (13/15), relational (17/20), and social (13/15) domains. Overall, 27.0% (77) of patients achieved scores consistent with the high quality of life definition. These patients did not differ in terms of median age (60 vs. 62), type of prosthesis (inflatable penile prostheses: 95% in both of the cases), and post-operative complications (10% vs. 14%) than those with lower quality of life score (all p > 0.1).…”

mentioning

confidence: 65%

“…Secondly, those patients with Peyronie's disease undergoing PPI may have presented with higher post-operative QoL and satisfaction scores in those cases when this difficult category of patients, who usually are young and present with very poor pre-operative sexual fitness after the onset of the disease, were successfully rehabilitated to satisfactory levels of sexual functioning. 27 In support of this apparently paradoxical finding, a number of studies have documented that the higher satisfaction scores for the surgical treatment of Peyronie's disease are achieved when a PPI (alone or concomitant with other straightening procedures) is performed, 28 versus the mere adoption of plication or grafting strategies. Thirdly, in the present series all of the Peyronie's disease patients were managed with manual modeling only during PPI and additional grafting or plication was not needed to correct their curvatures.…”

Section: Discussionmentioning

confidence: 99%

“…Firstly, we could speculate that in our series the application of a dedicated tool assessing more specifically the satisfaction with the device itself and its efficacy may have led to more reliable findings versus those studies using non‐validated questionnaires or questionnaires being developed for different purposes. Secondly, those patients with Peyronie's disease undergoing PPI may have presented with higher post‐operative QoL and satisfaction scores in those cases when this difficult category of patients, who usually are young and present with very poor pre‐operative sexual fitness after the onset of the disease, were successfully rehabilitated to satisfactory levels of sexual functioning 27 . In support of this apparently paradoxical finding, a number of studies have documented that the higher satisfaction scores for the surgical treatment of Peyronie's disease are achieved when a PPI (alone or concomitant with other straightening procedures) is performed, 28 versus the mere adoption of plication or grafting strategies.…”

Section: Discussionmentioning

confidence: 99%

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Which patient may benefit the most from penile prosthesis implantation?

et al. 2022

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Background Penile prosthesis implantation has been associated with overall good functional outcomes. Of relevance, some patients reported higher level of satisfaction and quality of life. Aim We investigated the profile of the patients who may benefit the most from penile prosthesis implantation. Materials and methods Data from a national multi‐institutional registry of penile prostheses including patients treated from 2014 to 2017 in Italy (Italian Nationwide Systematic Inventarization of Surgical Treatment for Erectile Dysfunction) were analyzed. All data have been prospectively recorded by 45 surgeons on a dedicated website (http://www.registro.andrologiaitaliana.it) and revised by a single data manager. Patients’ baseline characteristics were recorded. In order to simultaneously evaluate perceived penile prosthesis function and quality of life, all patients were re‐assessed at 1‐year follow‐up using the validated questionnaire Quality of Life and Sexuality with Penile Prosthesis. High quality of life after surgery was defined as a score higher than the 75th percentile in each of the subdomains of the Quality of Life and Sexuality with Penile Prosthesis questionnaire. Logistic regression analysis tested the association between clinical characteristics and high quality of life after penile prosthesis implantation. Results Follow‐up data were available for 285 patients (median age 60 years; interquartile range: 56–67) who underwent penile prosthesis implantation. Erectile dysfunction etiology was organic in 40% (114), pelvic surgery/radiotherapy in 39% (111), and Peyronie's disease in 21% (60) of the cases. Patients showed good overall Quality of Life and Sexuality with Penile Prosthesis scores at 1‐year follow‐up for functional (22/25), personal (13/15), relational (17/20), and social (13/15) domains. Overall, 27.0% (77) of patients achieved scores consistent with the high quality of life definition. These patients did not differ in terms of median age (60 vs. 62), type of prosthesis (inflatable penile prostheses: 95% in both of the cases), and post‐operative complications (10% vs. 14%) than those with lower quality of life score (all p > 0.1). At logistic regression analysis, erectile dysfunction etiology was the only factor independently associated with high quality of life at 1 year after surgery (p = 0.02). Patients treated for Peyronie's disease (odds ratio: 2.62; p = 0.01; 95% confidence interval: 1.20–5.74) were more likely to report better outcomes after accounting for age, post‐operative complications, and surgical volume. Conclusion Penile prosthesis implantation is associated with an overall good quality of life. The subset of patients affected by erectile dysfunction secondary to Peyronie's disease seemed to benefit the most from penile prosthesis implantation in terms of functional outcomes, relationship with their partners and the outside world, and perceived self‐image. The systematic use of validated questionnaires specifically addressed at evaluating quality of life and satisfaction af...

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mentioning

confidence: 65%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

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Which patient may benefit the most from penile prosthesis implantation?

et al. 2022

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“…Among all 171 papers, 18 reported more than one material, 12 of which included materials from different categories (six categories described before). The highest reported number of material types in one paper was five from three categories by Gamidov et al 14…”

Section: Resultsmentioning

confidence: 94%

“…The highest reported number of material types in one paper was five from three categories by Gamidov et al 14…”

Section: Total Population and Material-based Distributionmentioning

confidence: 94%

Chronological perspective of substitute materials used for the surgical treatment of Peyronie’s disease: A scoping review of literature

et al. 2022

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This comprehensive scoping review aimed to identify all up-to-date original publications relating to substitute materials used for the surgical treatment of Peyronie’s disease (PD), and characterize what material in which chronological trends were published in the current literature. Using the PCC framework (P: population, C: concept, and C: context), a search strategy was developed and used in four electronic databases, in addition to the Google scholar. All current published, in-press, and pre-print manuscripts with available English full-text were included. Eligible studies were required to be original research articles of any study design, reporting the usage of grafts on surgical treatment of PD. Included studies were reported in a narrative synthesis format. A total of 3379 articles were identified via an electronic search of databases and a total of 171 articles entered this scoping review. Most studies originated from Europe ( n = 72) and North America ( n = 66). Reports from the other continents increase in number in the 21st century. Highest number of the published papers was seen in 2001 to 2005 pentad. Autologous grafts (53.5%). Allografts (22.7%) and xenografts (15.7%) were the most frequently reported materials. Time flow of the used material and the alterations in trends for them is quite considerable. A global perspective of relevant publications on substitute materials in the surgical management of PD is presented in this review. The information in this summary may assist in establishing future research priorities in this area.

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