Long-term Prognosis in Attention-Deficit/Hyperactivity Disorder

Mannuzza, Salvatore; Klein, Rachel G.

doi:10.1016/s1056-4993(18)30114-7

Cited by 350 publications

(246 citation statements)

References 43 publications

Supporting

Mentioning

225

Contrasting

Unclassified

Order By: Relevance

“…In the DSM-IV, ODD, and CD are grouped together as externalizing disorders, together with ADHD. Although there is a high comorbidity for DBD and ADHD, and both ADHD and DBD children have been found to be at risk for antisocial behavior in adulthood (Mannuzza and Klein, 2000), previous research has shown that the relationship between low cortisol and externalizing behavior problems is specific for ODD/CD children, independent of comorbid ADHD (Snoek et al, 2004).…”

Section: Discussionmentioning

confidence: 99%

The Diurnal Cortisol Cycle in Delinquent Male Adolescents and Normal Controls

Popma

Doreleijers

Jansen

et al. 2007

Neuropsychopharmacol

View full text Add to dashboard Cite

Patterns of low hypothalamus-pituitary-adrenal (HPA) activity have been observed in antisocial groups. As conflicting results have been reported in children and adolescents, the aim of this study was to further investigate HPA activity in antisocial behavior by studying the relationship between the diurnal cortisol cycle, as well as the cortisol awakening response (CAR), and antisocial behavior in male adolescents. The diurnal cortisol cycle and the CAR during the first hour after awakening were compared between 12-to 14-year-old boys who attended a delinquency diversion program (DP), with and without a disruptive behavior disorder (DBD) (respectively DP + ; n ¼ 24 and DPÀ; n ¼ 65), and matched normal controls (NC; n ¼ 32). The DP + group, but not the DPÀ group, showed a significantly slower decrease of cortisol during the diurnal cycle than the NC group. Furthermore, the DP + group had significantly lower cortisol levels in the first hour after awakening as compared with the NC group. The results indicate altered HPA activity in delinquent boys with a DBD. Etiological mechanisms, directions for future research, and clinical implications are discussed.

show abstract

Section: Discussionmentioning

confidence: 99%

The Diurnal Cortisol Cycle in Delinquent Male Adolescents and Normal Controls

Popma

Doreleijers

Jansen

et al. 2007

Neuropsychopharmacol

View full text Add to dashboard Cite

show abstract

“…Due to the symptoms and complexity of the condition, there are a number of important long-term difficulties associated with ADHD. These include low academic attainment [10,11], which can persist into adulthood [12], poor executive functioning [13], poor social relationships, strained parent/child/sibling relationships [14] and problems with social interactions with peers [15]. This results in poorer quality of life and self-esteem in children and YP with ADHD [16,17].…”

Section: Introductionmentioning

confidence: 99%

What is the level of evidence for the use of currently available technologies in facilitating the self-management of difficulties associated with ADHD in children and young people? A systematic review

Powell¹,

Parker²,

Harpin

2017

Eur Child Adolesc Psychiatry

View full text Add to dashboard Cite

A number of technologies to help self-manage attention deficit hyperactivity disorder (ADHD) in children and young people (YP) have been developed. This review will assess the level of evidence for the use of such technologies. The review was undertaken in accordance with the general principles recommended in the Preferred Reporting Items for Systematic Reviews and Meta-Analysis. 7545 studies were screened. Fourteen studies of technology that aim to self-manage difficulties associated with ADHD in children and YP were included. Primary outcome measures were measures that assessed difficulties related to ADHD. Databases searched were MEDLINE, Web of Science (Core collection), CINAHL, the Cochrane Library, ProQuest ASSIA, PsycINFO and Scopus. The methodological quality of the studies was assessed. This review highlights the potential for the use of technology in paediatric ADHD management. However, it also demonstrates that current research lacks robustness; using small sample sizes, non-validated outcome measures and little psychoeducation component. Future research is required to investigate the value of technology in supporting children and YP with ADHD and a focus psychoeducation is needed.

show abstract

“…Beyond ADHD symptoms, externalizing behavior patterns, academic underachievement, and substance abuse, all of which have been elevated in follow-up studies of predominantly male samples (e.g., Barkley et al, 2008;Mannuzza & Klein, 2000), additional domains-for example, internalizing symptoms and self-harmful behavior-may be particularly salient for girls. In a prospective investigation of ADHD ascertained during the preschool years, comprising mostly boys (86%) but with a small female subgroup, Chronis-Tuscano et al (2010) found that probands showed higher rates of major depression, suicidal ideation, and suicide attempts than those in the matched comparison group.…”

mentioning

confidence: 99%

Prospective follow-up of girls with attention-deficit/hyperactivity disorder into adolescence: Evidence for continuing cross-domain impairment.

Hinshaw¹,

Owens²,

Sami³

et al. 2006

Journal of Consulting and Clinical Psychology

220

267

View full text Add to dashboard Cite

Objective: We performed a 10-year prospective follow-up of a childhood-ascertained (6 -12 years), ethnically and socioeconomically diverse sample of girls with attention-deficit/hyperactivity disorder (ADHD; N ϭ 140: combined type [ADHD-C] n ϭ 93; inattentive type [ADHD-I] n ϭ 47) plus a matched comparison group (N ϭ 88). Girls were recruited from schools, mental health centers, pediatric practices, and via advertisements; extensive evaluations confirmed ADHD versus comparison status. Method: Ten-year outcomes (age range 17-24 years; retention rate ϭ 95%) included symptoms (ADHD, externalizing, internalizing), substance use, eating pathology, self-perceptions, functional impairment (global, academic, service utilization), self-harm (suicide attempts, self-injury), and driving behavior. Results: Participants with childhood-diagnosed ADHD continued to display higher rates of ADHD and comorbid symptoms, showed more serious impairment (both global and specific), and had higher rates of suicide attempts and self-injury than the comparison sample, with effect sizes from medium to very large; yet the groups did not differ significantly in terms of eating pathology, substance use, or driving behavior. ADHD-C and ADHD-I types rarely differed significantly, except for suicide attempts and self-injury, which were highly concentrated in ADHD-C. Domains of externalizing behavior, global impairment, service utilization, and self-harm (self-injury and suicide attempts) survived stringent control of crucial childhood covariates (age, demographics, comorbidities, IQ). Conclusions: Girls with childhood ADHD maintain marked impairment by early adulthood, spreading from symptoms to risk for serious self-harm. Our future research addresses the viability of different diagnostic conceptions of adult ADHD and their linkages with core life impairments.

show abstract

Long-term Prognosis in Attention-Deficit/Hyperactivity Disorder

Cited by 350 publications

References 43 publications

The Diurnal Cortisol Cycle in Delinquent Male Adolescents and Normal Controls

The Diurnal Cortisol Cycle in Delinquent Male Adolescents and Normal Controls

What is the level of evidence for the use of currently available technologies in facilitating the self-management of difficulties associated with ADHD in children and young people? A systematic review

Prospective follow-up of girls with attention-deficit/hyperactivity disorder into adolescence: Evidence for continuing cross-domain impairment.

Contact Info

Product

Resources

About