Long-Term Quality-of-Life Outcomes After Body Contouring Surgery: Phase IV Results for the Body-QoL® Cohort

Suijker, Jaco; Troncoso, Ekaterina; Pizarro, Fernando; Montecinos, Sofia; Villarroel, Galia; Erazo, Cristián; V, Juan Pablo Cisternas; Andrades, Patricio; Benítez, Susana; Sepúlveda, Sergio A.; Danilla, Stefan

doi:10.1093/asj/sjx090

Cited by 15 publications

(5 citation statements)

References 32 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…The association between body mass index and patient-reported outcomes after surgery was observed in patients operated on for massive weight loss as well. 18 Interestingly, preoperative breast size did not correspond with the degree of chest/nipple dissatisfaction. Possible explanations may include (1) all preoperative participants applied for mastectomy and were (very) dissatisfied, and (2) chest dissatisfaction originating from gender dysphoria may relate primarily to the presence of female breasts, rather than the size of these breasts.…”

Section: Discussionmentioning

confidence: 96%

“…The relationship between patient-reported outcomes and mental health problems was observed earlier in transgender populations 9 , 10 and in patients undergoing post–weight loss surgery. 18 Mental health symptoms may indicate negative personality traits or lower self-esteem, or may even increase the risk of poorer objective outcomes. Therefore, it is of importance for surgeons in this field to understand the interplay between patient-reported outcomes and mental health and to refer to mental health professionals when necessary.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Subcutaneous Mastectomy Improves Satisfaction with Body and Psychosocial Function in Trans Men: Findings of a Cross-Sectional Study Using the BODY-Q Chest Module

Grift

Elfering

Greijdanus

et al. 2018

Plastic &Amp; Reconstructive Surgery

View full text Add to dashboard Cite

show abstract

Section: Discussionmentioning

confidence: 96%

Section: Discussionmentioning

confidence: 99%

Subcutaneous Mastectomy Improves Satisfaction with Body and Psychosocial Function in Trans Men: Findings of a Cross-Sectional Study Using the BODY-Q Chest Module

Grift

Elfering

Greijdanus

et al. 2018

Plastic &Amp; Reconstructive Surgery

View full text Add to dashboard Cite

show abstract

“…Gliomas are the most frequent malignant central nervous system tumours, accounting for more than 80% of all primary brain tumours ( 18 ). Because of glioma’s high heterogeneity and invasiveness, the 5-year survival rate of glioma patients remains very low ( 19 ), prompting people to aggressively investigate the pathophysiology and molecular targeted therapy of glioma.…”

Section: Discussionmentioning

confidence: 99%

Identification and validation of a 17-gene signature to improve the survival prediction of gliomas

Tong

Xia²,

Xu³

et al. 2022

Front. Immunol.

View full text Add to dashboard Cite

Gliomas are one of the most frequent types of nervous system tumours and have significant morbidity and mortality rates. As a result, it is critical to fully comprehend the molecular mechanism of glioma to predict prognosis and target gene therapy. The goal of this research was to discover the hub genes of glioma and investigate their prognostic and diagnostic usefulness. In this study, we collected mRNA expression profiles and clinical information from glioma patients in the TCGA, GTEx, GSE68848, and GSE4920 databases. WGCNA and differential expression analysis identified 170 DEGs in the collected datasets. GO and KEGG pathway analyses revealed that DEGs were mainly enriched in gliogenesis and extracellular matrix. LASSO was performed to construct prognostic signatures in the TCGA cohort, and 17 genes were used to build risk models and were validated in the CGGA database. The ROC curve confirmed the accuracy of the prognostic signature. Univariate and multivariate Cox regression analyses showed that all independent risk factors for glioma except gender. Next, we performed ssGSEA to demonstrate a high correlation between risk score and immunity. Subsequently, 7 hub genes were identified by the PPI network and found to have great drug targeting potential. Finally, RPL39, as one of the hub genes, was found to be closely related to the prognosis of glioma patients. Knockdown of RPL39 in vitro significantly inhibited the proliferation and migration of glioma cells, whereas overexpression of RPL39 had the opposite effect. And we found that knockdown of RPL39 inhibited the polarization and infiltration of M2 phenotype macrophages. In conclusion, our new prognosis-related model provides more potential therapeutic strategies for glioma patients.

show abstract

“…QoL ® por nuestro equipo 30 , ha permitido evaluar el impacto asociado a los procedimientos de cirugía de contorno corporal en la calidad de vida de los pacientes tanto con y sin antecedente de pérdida masiva de peso 31 . Nuestros resultados muestran un cambio favorable en la calidad de vida poscirugía de contorno corporal (aumento de 41,5 puntos) y que este se mantiene en el tiempo a largo plazo (p = 0,112) 32 . Estos resultados son concordantes con lo publicado por Klassen 33 y Van der Beek 34 .…”

Section: Discussionunclassified

Cirugía de contorno corporal en pacientes con pérdida masiva de peso en un hospital universitario. Estudio de frecuencias

et al. 2018

View full text Add to dashboard Cite

Introduction: Massive weight loss in obese, has beneficial health effects, however patients usually presents excessive adiposity and redundant skin, that generates physical and psychological problems. The body contouring surgery helps to modify the contour of the body to achieve aesthetic harmony. There are few national studies that describe the epidemiology of body contour surgery in patients with massive weight loss. Objectives: Describes a series of patients with massive weight loss with body contour surgery and its complications. Materials and Methods: A prospective series of patients with body contouring surgery with a history of low body mass, between January 2013 and June 2016, in a university hospital. Patients with incomplete information or operated at another center were excluded. Descriptive statistics was used. Results: 120 patients with body contouring surgery and low weight mass were included. Age of 38.4 ± 10.4 years, 105 (87.5%) were women. 110 (91.67%) were bariatric patients. BMI of 26.56 ± 3.26 kg/m 2 and a weight loss of 39.06 ± 14.17 Kg were reached previous the contouring surgery. The most frequent surgery was the standard abdominoplasty 79 (65.83%), followed by mastopexy with implants 21 (17.5%). 1 (0.83%) presented major complication and 33 (27.5%) had a minor complication during the postoperative period. Discussion: This series presents results similar to other authors, with a lower rate of postoperative complications. Conclusion: The Body contouring surgery are safe procedures, which provides a solution to the bodily sequels after massive weight loss according to our experience.

show abstract

Long-Term Quality-of-Life Outcomes After Body Contouring Surgery: Phase IV Results for the Body-QoL® Cohort

Cited by 15 publications

References 32 publications

Subcutaneous Mastectomy Improves Satisfaction with Body and Psychosocial Function in Trans Men: Findings of a Cross-Sectional Study Using the BODY-Q Chest Module

Subcutaneous Mastectomy Improves Satisfaction with Body and Psychosocial Function in Trans Men: Findings of a Cross-Sectional Study Using the BODY-Q Chest Module

Identification and validation of a 17-gene signature to improve the survival prediction of gliomas

Cirugía de contorno corporal en pacientes con pérdida masiva de peso en un hospital universitario. Estudio de frecuencias

Contact Info

Product

Resources

About