“…A range of multi-millennial projections available so far have focused primarily on the evolution of surface air temperature (SAT), atmospheric CO 2 , oceanic pH, sea level and the Atlantic Meridional Overturning Circulation (AMOC) (Plattner et al, 2008;Eby et al, 2009;Zickfeld et al, 2013;Golledge et al, 2015;Winkelmann et al, 2015;Clark et al, 2016;Zickfeld et al, 2017;Pfister and Stocker, 2016;Lord et al, 2016;Ehlert and Zickfeld, 2017). Fewer long-term model simulations have focused on oceanic oxygen (Yamamoto et al,15 2015; Matear and Hirst, 2003;Schmittner et al, 2008;Mathesius et al, 2015). We show that the oceanic oxygen equilibration timescale is considerably longer than its thermal equilibration timescale and that oceanic oxygen changes are dominated by changes in Atlantic and Indo-Pacific overturning, predictive variables to be considered in future multi-millennial projections with General Circulation Models (GCMs).…”