Long-Term Results of Extracorporeal Shockwave Therapy for Peyronie's Disease

Srirangam, Shalom J.; Manikandan, Ramaswamy; Hussain, Jawad; Collins, Gerald N.; O'reilly, P. H.

doi:10.1089/end.2006.20.880

Cited by 28 publications

(12 citation statements)

References 20 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Extracorporeal shockwave therapy (ESWT), which was introduced from urologists in order to destroy kidney stones, has been tested in penile fibromatosis (Evidence level Ib) [5]. Another study reported that about half of all ESWT treated patients had a significant reduction in penile angulation [6]. Given these observations in penile fibromatosis, we started to perform a randomized-controlled trial to evaluate high-energy focussed ESWT in palmar fibromatosis, Dupuytren’s contracture (DupuyShock) [7].…”

Section: Resultsmentioning

confidence: 99%

High-energy focussed extracorporeal shockwave therapy reduces pain in plantar fibromatosis (Ledderhose’s disease)

Knobloch

Vogt

2012

BMC Res Notes

View full text Add to dashboard Cite

BackgroundPlantar fibromatosis is a benign disease creating nodules on the medial plantar side of affected patients. While surgical removal is regarded as the therapeutic mainstay, recurrence rates and impairment of daily activities remains substantial. High-energy focussed extracorporeal shockwave therapy has been suggested to be potentially effective in plantar fibromatosis in terms of pain reduction.HypothesisHigh-energy focussed extracorporeal shockwave therapy reduces pain in plantar fibromatosis.FindingsA total number of six patients (5 males, 58±4 years) were included with plantar fibromatosis (Ledderhose’s disease) associated with pain. Three patients were operated on previously, one had concomitant Dupuytren’s contracture. High-energy focussed ESWT was applied using a Storz Duolith SD1 (2000 impulses, 3 Hz, 1.24 mJ/mm2) in two sessions with 7 days between. Pain was 6±2 at baseline, 2±1 after 14 days and 1±1 after 3 months. Softening of the nodules was noted by all patients. No adverse effects were noted.ConclusionsHigh-energy focussed extracorporeal shockwave energy reduces pain in painful plantar fibromatosis (Morbus Ledderhose). Further large-scale prospective trials are warranted to elucidate the value of high-energy focussed extracorporeal shockwave therapy (ESWT) in plantar fibromatosis in terms of recurrence and efficacy.

show abstract

Section: Resultsmentioning

confidence: 99%

High-energy focussed extracorporeal shockwave therapy reduces pain in plantar fibromatosis (Ledderhose’s disease)

Knobloch

Vogt

2012

BMC Res Notes

View full text Add to dashboard Cite

show abstract

“…Although initial studies failed to demonstrate any efficacy of extracorporeal shock wave therapy (ESWT) for the treatment of PD [142][143][144], more recent studies suggest a possible role of ESWL in the reduction of pain [145][146][147].…”

Section: Eswlmentioning

confidence: 99%

The Management of Peyronie’s Disease: Evidence-based 2010 Guidelines

Ralph,

Gonzalez-Cadavid,

Mirone

et al. 2010

The Journal of Sexual Medicine

320

437

View full text Add to dashboard Cite

Introduction The field of Peyronie’s disease is evolving and there is need for a state-of-the-art information in this area. Aim To develop an evidence-based state-of-the-art consensus report on the management of Peyronie’s disease. Methods To provide state-of-the-art knowledge regarding the prevalence, etiology, medical and surgical management of Peyronie’s Disease, representing the opinion of leading experts developed in a consensus process over a 2-year period. Main Outcome Measures Expert opinion was based on grading of evidence-based medical literature, widespread internal committee discussion, public presentation, and debate. Conclusions The real etiology of Peyronie’s disease and the mechanisms of formation of the plaque still remain obscure. Although conservative management is obtaining a progressively larger consensus among the experts, surgical correction still remains the mainstay treatment for this condition.

show abstract

“…Nevertheless, ESWT is described as a nonsurgical treatment of Peyronie's diseases in humans. This disorder of the penis is characterized by dense, fibrous plaque formation in the tunica albuginea sometimes associated with calcification or ossification and clinically causing pain, distortion, and erection problems 12 . Despite the lack of conclusive evidence of effects of ESWT 13 in the treatment of Peyronie's disease, it was shown to have minimal adverse effects and to be safe.…”

Section: Discussionmentioning

confidence: 99%

The Use of Radial Extracorporeal Shockwave Therapy in the Treatment of Urethral Urolithiasis in the Horse: A Preliminary Study

Verwilghen

Ponthier

Galen

et al. 2008

Veterinary Internal Medicne

View full text Add to dashboard Cite

Background: Radial extracorporeal shockwave therapy (ESWT) is widely used in equine practice for the treatment of orthopedic problems. However, its original use as a lithotripsy device in human and canine urology led us to postulate that it could be used as an alternative to the surgical treatment of urethral calculi in horses.Hypothesis: Radial ESWT can easily and safely fragment calculi in the distal urethra of the horse. Animals: Two postmortem cases and 1 live case of obstructive urinary disease admitted at the Veterinary Teaching Hospital of Liege.Methods: A radial shockwave device was directly applied to the urethra in an attempt to fragment calculi. An ex vivo trial was performed on the same retrieved calculi to investigate pressure settings in order to obtain complete fragmentation of the calculus.Results: In all cases, radial ESWT was able to fragment the calculus partially, enabling retrieval of the remaining fragments via the urethra. Much higher pressure settings than those used for in vivo partial fragmentation were necessary to obtain complete destruction of the calculi ex vivo.Conclusions and Clinical Importance: This brief report suggests the use of radial ESWT as a safe and useful alternative to more invasive surgical management of urethral calculi in horses.

show abstract

Long-Term Results of Extracorporeal Shockwave Therapy for Peyronie's Disease

Cited by 28 publications

References 20 publications

High-energy focussed extracorporeal shockwave therapy reduces pain in plantar fibromatosis (Ledderhose’s disease)

High-energy focussed extracorporeal shockwave therapy reduces pain in plantar fibromatosis (Ledderhose’s disease)

The Management of Peyronie’s Disease: Evidence-based 2010 Guidelines

The Use of Radial Extracorporeal Shockwave Therapy in the Treatment of Urethral Urolithiasis in the Horse: A Preliminary Study

Contact Info

Product

Resources

About