Long-term Results Using Adjunctive Mitomycin C in Optic Nerve Sheath Decompression for Pseudotumor Cerebri

Spoor, Thomas C.; McHenry, John G.; Shin, Dong Ho

doi:10.1016/s0161-6420(95)30759-2

Cited by 35 publications

(19 citation statements)

References 13 publications

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“…In that series, revision ONSD was performed with stabilisation of vision in about 50% of cases. 15 Adjuvant mitomycin C has been used in such cases apparently without adverse effects to the optic nerve, 16,17 although there is a dosedependent toxic effect on the VEP in a rabbit model. In our clinic, patients with failed ONSD are generally referred for shunting rather than revision surgery.…”

Section: Long-term Results From Onsd and Revision Onsdmentioning

confidence: 99%

Optic nerve disorders: role of canal and nerve sheath decompression surgery

Acheson

2004

Eye

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Optic nerve sheath decompression (ONSD) maintains a role in the management of visual loss complicating papilloedema in selected patients primarily with idiopathic intracranial hypertension. The evidence base for this intervention is reviewed and audit data on visual outcomes for patients with acute, chronic, and atrophic forms of papilloedema are contrasted. Optic canal decompression has a role in the management of compressive optic neuropathies complicating mass lesions arising from paranasal sinuses and intracranially and can be achieved by transethmoidal, transbasal, and open craniotomy routes. The evidence base supporting this intervention in traumatic optic neuropathy and in primary bone disease causing canal stenosis (in particular fibrous dysplasia) is reviewed where the indications are more controversial.

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Section: Long-term Results From Onsd and Revision Onsdmentioning

confidence: 99%

Optic nerve disorders: role of canal and nerve sheath decompression surgery

Acheson

2004

Eye

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“…7 Up to 35 per cent initially successful optic nerve sheath decompressions failed due to excessive scarring, brosis, vascularity and fat adhesion at the surgical site. 8 We feel optic nerve sheath decompression of the intracanalicular portion will be more effective than the orbital portion, as it is without any fat and gives better compensatory space for distension. 5 The endoscopic method is free from complications of orbitotomy such as iris sphincter paresis and accommodation paresis.…”

Section: Discussionmentioning

confidence: 98%

Modified endoscopic optic nerve decompression in idiopathic intracranial hypertension

2003

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“…Prompt medical and subsequent surgical treatment is essential to maintaining and preserving visual function. CSF diversion reduces visual decline and improves visual acuity, but in a few cases despite maximal surgical intervention, progressive decline in visual function can occur due to a progressive optic neuropathy secondary to a elevation in CSF pressure after an ONSF [33] irreversible damage to the optic nerve prior to ONSF [33,34], a fibrosis of the fenestration [35], a retinal reperfusion injury post ONSF [36], shunt failure, unmodified risk factors M a n u s c r i p t 13 especially obesity or poor visual function ( VA, VF, CV) at initial referral [17]. The latter three, were significant factors in our patients who had progressive worsening of their visual function.…”

Section: Discussionmentioning

confidence: 99%