Long-term safety and durability of novel intra-aortic percutaneous mechanical circulatory support device

Lu, Carolyne; Krisher, James A.; Benavides, Omar M.; Palmer, Aaron Zeff; Edidin, Avram A.; Durst, Chris; Heuring, Jace

doi:10.1016/j.healun.2022.10.005

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2024

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“…This device has demonstrated efficacy in enhancing perfusion of the kidneys to facilitate diuresis without the penalty of renal injury [2][3][4][5]. Its long-term safety and durability has been evaluated in both animal models and humans, with its first human pilot study demonstrating positive results [2][3][4][5][6]. Prior to this case, a single unmodulated nominal setting was prescribed.…”

Section: Discussionmentioning

confidence: 99%

First Description of Novel End-Organ Effects by Speed Modulation Using the Aortix™ Device

Bhandari,

Dunham,

Bassily

et al. 2024

Case Reports in Cardiology

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Aortix™ is a novel percutaneous mechanical circulatory support device designed to facilitate diuresis in patients with cardiorenal syndrome. We describe for the first time the development of end-organ hypoperfusion from excess blood acceleration at the nominal setting and demonstrate through temporal-perfusion marker curves, the potential for speed modulation to optimize results. This will inform future device development and investigation of patient-specific device titration.

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