Long-Term Single-Center Results of Management of Ethmoid Adenocarcinoma: 95 Patients over 28 Years

Gabory, L. de; Maunoury, A.; Maurice-Tison, S.; Abdulkhaleq, Habib Merza; Darrouzet, V.; Bébéar, J. P.; Stoll, D.

doi:10.1245/s10434-010-0933-3

Cited by 58 publications

(73 citation statements)

References 42 publications

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“…De Gabory et al [11] in their 2010 study detected a mean recurrence rate involving ADK of 30% in the literature, in accordance with that of our study.…”

Section: Discussionsupporting

confidence: 93%

See 1 more Smart Citation

Postoperative Correlation of Radiological and Surgical Findings in Management of Ethmoid Sinus Adenocarcinoma

Prampart¹,

Djennaoui²,

Çiftci³

et al. 2017

Arch Otolaryngol Rhinold

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“…De Gabory et al [11] in their 2010 study detected a mean recurrence rate involving ADK of 30% in the literature, in accordance with that of our study.…”

Section: Discussionsupporting

confidence: 93%

“…endoscopic optics, endonasal instrumentation, intensitymodulated conformal radiotherapy…) clinical evolution nevertheless demonstrates a high rate of locoregional recurrence (30% of cases on average) involving complications principally due to complex anatomy and proximity to important anatomic structures [11][12][13].…”

Section: Discussionmentioning

confidence: 99%

Postoperative Correlation of Radiological and Surgical Findings in Management of Ethmoid Sinus Adenocarcinoma

Prampart¹,

Djennaoui²,

Çiftci³

et al. 2017

Arch Otolaryngol Rhinold

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“…Our DFS, CSS and OS of 58, 60 and 58 % are similar to other European published series [10]. These values are also similar to the previous published results of adenocarcinomas at our institution [6], which found had values of CSS and OS at 5 years of 69 and 49 %.…”

Section: Discussionsupporting

confidence: 92%

“…Many patients are diagnosed in advanced stages [10], as occurred in our series with more than two thirds of the patients presenting in T3-T4 stages and with a mean time between first symptoms and diagnosis of 7 months. The most common symptoms were nasal obstruction, rhinorrhoea and epistaxis, and the ethmoid sinus was the most frequent affected sinus; this data are similar to other previous published works [4].…”

Section: Discussionsupporting

confidence: 52%

Adenocarcinomas of the sinonasal tract: a case series from an Oncology Centre in Northern Portugal

Veloso-Teles

Ribeiro

Silva

et al. 2014

Eur Arch Otorhinolaryngol

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Sinonasal malignant neoplasms are rare and adenocarcinomas account for 10-20 % of these cancers. Our aim is to characterise the clinical presentation, risk factors and outcomes of patients with adenocarcinoma treated at our institution. Retrospective review of medical records of patients with sinonasal adenocarcinomas, treated at IPO-Porto from January 2008 until December 2012. Twenty-eight patients with adenocarcinomas were selected from a total of 53 patients with sinonasal cancers. There was a male predominance (93 %), a mean age at diagnosis of 56 years and a rate of occupational wood dust exposure of 71 %. The most common treatment option was surgery followed by adjuvant radiotherapy. The 5 year disease-free and cancer-specific survival was 58 and 60 %, respectively. The following factors had negative impact on disease-free survival: advanced AJCC stage (p = 0.014); skull base invasion (p = 0.002); poorly differentiated or mucinous subtypes histology (p = 0.034) and imaging findings of residual tumour before adjuvant radiotherapy (p < 0.001). Endoscopic tumour resection was not associated with adverse outcomes. The role of volume-modulated arch therapy in the treatment of sinonasal tumours has to be clarified. The higher rate of adenocarcinomas among sinonasal cancers in this series comparing with previous reports, even from our institution, suggests that this pathology is rising in Northern Portugal. Despite substantial local failure, sinonasal adenocarcinomas have a relatively favourable prognosis in terms of cancer-specific survival.

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“…Many studies dealing with ADC often compare patients with different origins, different stages or histological subtypes pooled from several institutions [2] or included during a long period of time [9,10]. As long as complete extirpation of the tumour is achieved, the current debate in ADC management is about the most appropriate surgical approach.…”

Section: Discussionmentioning

confidence: 99%

Comparison of endoscopic and external resections for sinonasal instestinal-type adenocarcinoma

Mortuaire

Leroy

Vandenhende‐Szymanski

et al. 2016

Eur Arch Otorhinolaryngol

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Endoscopic sinus surgery (ESS) is considered as a valid option in the management of nasal adenocarcinoma (ADC). Comparative studies with open approaches are still required. A monocentric retrospective study was carried out from May 2002 to December 2013, including 43 patients with intestinal-type adenocarcinoma of the ethmoid sinus. Non-resectable tumours or recurrences were excluded. Before 2008, open approach with lateral rhinotomy (LR) was performed as the gold standard of treatment. From 2008, ESS was systematically used as a first-line option as long as a complete resection was achievable. Adjuvant radiation therapy was delivered (RT) for all the patients. LR and ESS were performed in, respectively, 23 and 20 patients. The two groups were comparable in terms of age, occupational dust exposure, histopathological subtypes, and T stage based on the pathological assessment of the specimen (10 pT2, 26 pT3, 2 pT4a, and 5 pT4b). The tumour origin was mainly located in the olfactory cleft with the involvement of the cribriform plate in 60 % of patients. No major complication was observed in ESS group with a reduced hospital stay (5.6 vs 7.6 days). The disease-free survival was not different between LR and ESS groups over a mean follow-up period of 6.6 years. Even for local advanced stages with skull base involvement, we confirm the reliability and the advantages of ESS in terms of oncological outcomes and morbidity. We advocate complete excision of the olfactory cleft to ensure an appropriate control of the tumoral origin.

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Long-Term Single-Center Results of Management of Ethmoid Adenocarcinoma: 95 Patients over 28 Years

Cited by 58 publications

References 42 publications

Postoperative Correlation of Radiological and Surgical Findings in Management of Ethmoid Sinus Adenocarcinoma

Postoperative Correlation of Radiological and Surgical Findings in Management of Ethmoid Sinus Adenocarcinoma

Adenocarcinomas of the sinonasal tract: a case series from an Oncology Centre in Northern Portugal

Comparison of endoscopic and external resections for sinonasal instestinal-type adenocarcinoma

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