Long-term Survival After Radiofrequency Ablation of Complex Unresectable Liver Tumors

Amersi, Farin

doi:10.1001/archsurg.141.6.581

Cited by 113 publications

(82 citation statements)

References 27 publications

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“…Radiofrequency ablation therapy in the treatment of small renal tumors has been an alternative to other methods of treatment due to high radiological and oncological efficacy [2]. Radiofrequency ablation therapy is applied with success in the treatment of liver, kidney, lung, bone and breast tumors [3]. Radiofrequency ablation therapy can be performed to treat small renal cell carcinoma by both percutaneous and laparoscopic approaches.…”

Section: Sirmentioning

confidence: 99%

Radiofrequency Ablation Treatment in Small Renal Masses

Karakose

Yüksel

2014

Med Sci and Discov

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Section: Sirmentioning

confidence: 99%

Radiofrequency Ablation Treatment in Small Renal Masses

Karakose

Yüksel

2014

Med Sci and Discov

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“…Although the approach of RFA was not shown to influence survival, there was a trend towards a higher rate of recurrence with percutaneous RFA (PcRFA) (15.1%) compared to open (6.7%) and laparoscopy (9%) in a study by Bleicher et al of 153 patients treated for a total of 447 liver tumours [8]. In addition, several studies had consistently reported significantly higher complication rates with PcRFA relative to operative approaches [9,10]. Despite the perceived technical simplicity with PcRFA, the cooperation of patients' respiratory effort following sedation poses difficulty in accurate probe placement [11].…”

Section: Delivery Of Rfamentioning

confidence: 99%

Resection and Ablation for Colorectal Liver Metastases

Ng¹

2013

J Gastrointest Dig Syst

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The surgical approach combining resection and ablation allows for a greater number of patients with colorectal liver metastases who would otherwise be considered to have unresectable disease to be given an opportunity to undergo a curative attempt surgery. Ablation results in local destruction of tumour and is often employed in lesions that are in locations which are not easily resectable. This may involve the use of radiofrequency ablation that causes thermal destruction or cryotherapy that freezes tumours. This review examined the literature reporting resection and ablation of colorectal liver metastases.

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“…Radiofrequency ablation (RFA) is an important and minimal-invasive treatment option for hepatic tumors and metastases [1][2][3][4][5][6][7]. It belongs to the energy-based ablation modalities and relies on proper needle electrode placement into the tumor via an open, laparoscopic or percutaneous approach.…”

Section: Introductionmentioning

confidence: 99%

Characterization of benign periablational enhancement following multipolar radiofrequency ablation using perfusion CT in an in-vivo porcine liver model

Vahldiek

Thieme

Gemeinhardt

et al. 2017

JCB

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Abstract. PURPOSE:Thermal ablation is an important interventional option in the management of liver tumors. Immediate postablational imaging regularly shows periablational enhancement. This peripheral hyperperfusion may induce heat-sink effects which could contribute to incomplete tumor ablation. To reduce the effect of hyperperfusion the feeding vessels source must be known. The aim of this study was to dynamically characterize the type of blood supply of the periablational enhancement zone immediately after hepatic radiofrequency ablation (RFA) using perfusion CT. METHODS:We used an in-vivo porcine liver model. Multipolar RFA was performed in healthy pig livers. Immediate postablational perfusion CT was acquired. The contrast enhancement over time of the peripheral ablation zone, the aorta and the portal vein were recorded. Time differences of the peak periablational enhancement to the peak arterial perfusion and to the peak portalvenous perfusion were calculated and analyzed. RESULTS: The perfusion peak of the periablational enhancement zone always occurred in mean 8.1 s after the arterial peak in the aorta and in mean 16.9 s before the peak in the portal vein. CONCLUSIONS: Benign periablational enhancement is a result of primary arterial and not portalvenous hyperperfusion. In order to reduce heat sink effects, peri-ablational arterial balloon occlusion or transarterial chemoembolization may be beneficial during RFA.

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Long-term Survival After Radiofrequency Ablation of Complex Unresectable Liver Tumors

Abstract: Hypothesis: Radiofrequency ablation (RFA) may improve survival of high-risk patients with unresectable and refractory tumors.Design: Retrospective analysis of a prospective database.

Cited by 113 publications

References 27 publications

Radiofrequency Ablation Treatment in Small Renal Masses

Radiofrequency Ablation Treatment in Small Renal Masses

Resection and Ablation for Colorectal Liver Metastases

Characterization of benign periablational enhancement following multipolar radiofrequency ablation using perfusion CT in an in-vivo porcine liver model

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