Long-term Survivors with Adult Acute Leukemia in Complete Remission: Complications and Return to Work

Abstract

For addressing, and eventually being able to predict and prevent, both disease-related complications and changes in social status in long-term acute leukemia survivors, the follow-up is the most important factor after treatment. To this end, we assessed the complications following the attainment of complete remission in adult acute leukemia patients and the changes in social status of patients surviving more than 5 years after disease onset. In our study population of 42 survivors, 24 (57.1%) suffered from various combinations of 18 types of identified complications including posttransfusion hepatitis, diabetes mellitus, and idiopathic osteonecrosis. Regarding fertility, 9 live births were recorded in this cohort, from 2 female patients and the partner of a male patient. Of these 42 long-term survivors, at the time of this report 48.5% were working full- or part-time, 9.0% were unemployed, 30.3% were homemakers, and 12.2% were retired.

Cancer and the risk for taking early retirement pension: A Danish cohort study

“…Nevertheless, a relative risk for employment of 0.70 (95% CI 0.6-0.8) and an odds ratio for quitting working of 3.03 (95% CI 1.2-7.4) in two large studies from Finland [12] and the USA [13], respectively, support our finding of an increased risk for taking ERP among leukaemia patients. Studies in Japan and the USA did not, however, observe an effect among leukaemia survivors [7,8], but the small number (n542) of patients in the Japanese study and the low response rate (v50%) in the cross-sectional study in the USA cast doubt on these findings.…”

“…Up to 50% of all cancer patients are confronted with work-related problems after treatment for cancer [4,5], determined by factors such as cancer site [6][7][8][9], age [8,10], income [10], job type [11,12] and late effects [13]. In a society where social benefits are provided by the state irrespective of the socioeconomic position of the recipient, ERP might be a good alternative to problems at work or unemployment after diagnosis and treatment for cancer.…”

Cytochrome P4501A1 and Glutathione S Transferase Gene Polymorphisms in Patients with Aplastic Anemia in India

“…The incidence of AA appears to be relatively high in Asia compared with the West [17,18,19]. Recently, in a population-based study, it was documented that the incidence of AA in Bangkok was approximately twice as high as in Europe or Israel [20].…”