Long-term treatment response to continuous cycling course in bipolar disorders: A meta-analysis.

Tundo, Antonio; Crescenzo, Franco De; Gori, Davide; Cavalieri, Paola

doi:10.1016/j.jad.2018.08.067

Cited by 3 publications

(3 citation statements)

References 19 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…We Within the context of those substantial differences, it is worth noting that the proportions of WMH respondents who reported being helped were higher than the proportion of bipolar patients found to have good long-term treatment response in observational studies of treatment samples, 34 possibly suggesting that patients in the community have a broader definition of helpfulness than the definitions used in clinical studies. We also found less consistent evidence for significant predictors of patient-reported helpfulness than in the clinical literature on predictors of treatment response, [35][36][37] suggesting that the determinants of patient perceptions of treatment helpfulness might be different from the determinants of clinical definitions of treatment success.…”

Section: Discussionmentioning

confidence: 91%

Perceived helpfulness of bipolar disorder treatment: Findings from the World Health Organization World Mental Health Surveys

et al. 2021

View full text Add to dashboard Cite

Bristol-Myers Squibb. We thank the staff of the WMH Data Collection and Data Analysis Coordination Centres for assistance with instrumentation, fieldwork, and consultation on data analysis. None of the funders had any role in the design, analysis, interpretation of results, or preparation of this manuscript. The views and opinions expressed in this report are those of the authors and should not be construed to represent the views of the World Health Organization, other sponsoring organizations, agencies, or governments. The Argentina survey -Estudio Argentino de Epidemiología en Salud Mental (EASM) -was supported by a grant from the

show abstract

Section: Discussionmentioning

confidence: 91%

Perceived helpfulness of bipolar disorder treatment: Findings from the World Health Organization World Mental Health Surveys

et al. 2021

View full text Add to dashboard Cite

show abstract

“…Several reviews of the subject exist in the current literature. These include narrative reviews[ 4 , 24 , 27 , 30 , 32 ], systematic reviews[ 6 , 16 , 17 , 29 , 31 ], and meta-analyses[ 5 , 18 , 20 , 21 , 33 ] ( includes a complete list of all the reviews consulted).…”

Section: Introductionmentioning

confidence: 99%

Role of adjunctive nonpharmacological strategies for treatment of rapid-cycling bipolar disorder

Chakrabarti,

Jolly,

Singh

et al. 2023

World J Psychiatry

View full text Add to dashboard Cite

Rapid-cycling bipolar disorder (RCBD) is a phase of bipolar disorder defined by the presence of ≥ 4 mood episodes in a year. It is a common phenomenon characterized by greater severity, a predominance of depression, higher levels of disability, and poorer overall outcomes. It is resistant to treatment by conventional pharmacotherapy. The existing literature underlines the scarcity of evidence and the gaps in knowledge about the optimal treatment strategies for RCBD. However, most reviews have considered only pharmacological treatment options for RCBD. Given the treatment-refractory nature of RCBD, nonpharmacological interventions could augment medications but have not been adequately examined. This review carried out an updated and comprehensive search for evidence regarding the role of nonpharmacological therapies as adjuncts to medications in RCBD. We identified 83 reviews and meta-analyses concerning the treatment of RCBD. Additionally, we found 42 reports on adjunctive nonpharmacological treatments in RCBD. Most of the evidence favoured concomitant electroconvulsive therapy as an acute and maintenance treatment. There was preliminary evidence to suggest that chronotherapeutic treatments can provide better outcomes when combined with medications. The research on adjunctive psychotherapy was particularly scarce but suggested that psychoeducation, cognitive behavioural therapy, family interventions, and supportive psychotherapy may be helpful. The overall quality of evidence was poor and suffered from several methodological shortcomings. There is a need for more methodologically sound research in this area, although clinicians can use the existing evidence to select and individualize nonpharmacological treatment options for better management of RCBD. Patient summaries are included to highlight some of the issues concerning the implementation of adjunctive nonpharmacological treatments.

show abstract

“…Consequently, patients with psychiatric comorbidities such as SUDs are often excluded. Moreover, a substantial proportion of BD patients show inadequate response to medication ( 18 ). Medication patterns in community BD samples and naturalistic settings often diverge from guidelines, increasing the risk of poor clinical outcome ( 19 ).…”

Section: Introductionmentioning

confidence: 99%

Preventive Medication Patterns in Bipolar Disorder and Their Relationship With Comorbid Substance Use Disorders in a Cross-National Observational Study

et al. 2022

View full text Add to dashboard Cite

ObjectiveThe potential role of sub-optimal pharmacological treatment in the poorer outcomes observed in bipolar disorder (BD) with vs. without comorbid substance use disorders (SUDs) is not known. Thus, we investigated whether patients with BD and comorbid SUD had different medication regimens than those with BD alone, in samples from France and Norway, focusing on compliance to international guidelines.MethodsSeven hundred and seventy patients from France and Norway with reliably ascertained BD I or II (68% BD-I) were included. Medication information was obtained from patients and hospital records, and preventive treatment was categorized according to compliance to guidelines. We used Bayesian and regression analyses to investigate associations between SUD comorbidity and medication. In the Norwegian subsample, we also investigated association with lack of medication.ResultsComorbid SUDs were as follows: current tobacco smoking, 26%, alcohol use disorder (AUD), 16%; cannabis use disorder (CUD), 10%; other SUDs, 5%. Compliance to guidelines for preventive medication was lacking in 8%, partial in 44%, and complete in 48% of the sample. Compliance to guidelines was not different in BD with and without SUD comorbidity, as was supported by Bayesian analyses (highest Bayes Factor = 0.16). Cross national differences in treatment regimens led us to conduct country-specific adjusted regression analyses, showing that (1) CUD was associated with increased antipsychotics use in France (OR = 2.4, 95% CI = 1.4–3.9, p = 0.001), (2) current tobacco smoking was associated with increased anti-epileptics use in Norway (OR = 4.4, 95% CI = 1.9–11, p < 0.001), and (3) AUD was associated with decreased likelihood of being medicated in Norway (OR = 1.2, 95% CI = 1.04–1.3, p = 0.038).ConclusionSUD comorbidity in BD was overall not associated with different pharmacological treatment in our sample, and not related to the level of compliance to guidelines. We found country-specific associations between comorbid SUDs and specific medications that warrant further studies.

show abstract

Long-term treatment response to continuous cycling course in bipolar disorders: A meta-analysis.

Cited by 3 publications

References 19 publications

Perceived helpfulness of bipolar disorder treatment: Findings from the World Health Organization World Mental Health Surveys

Perceived helpfulness of bipolar disorder treatment: Findings from the World Health Organization World Mental Health Surveys

Role of adjunctive nonpharmacological strategies for treatment of rapid-cycling bipolar disorder

Preventive Medication Patterns in Bipolar Disorder and Their Relationship With Comorbid Substance Use Disorders in a Cross-National Observational Study

Contact Info

Product

Resources

About