Long-term use of Vitamin-C in chronic obstructive pulmonary disease

Dey, Debkanya; Sengupta, Sayoni; Bhattacharyya, Parthasarathi

doi:10.4103/lungindia.lungindia_959_20

Cited by 2 publications

(2 citation statements)

References 4 publications

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“…Similarly, people that use combustible tobacco and consume a diet rich with vitamin C exhibit slower rates of pulmonary decline (FEV 1 ) when compared to those with low vitamin C intake [ 112 ]. This finding was confirmed in patients with COPD, with daily doses of 400 milligrams of vitamin C associated with better lung function (FEV 1 percent predictive and FEV 1 /FVC) [ 15 ], and daily doses of 2 g/day were associated with fewer pulmonary exacerbations over a six-month period [ 113 ]. Additionally, significant improvements in antioxidant capacity and vascular function were also observed in patients with COPD (GOLD stage I–IV) after an acute dose of a combination of vitamin C, vitamin E, and α-lipoic acid [ 114 ].…”

Section: Vitamins a B C And Ementioning

confidence: 90%

“…In regard to vitamin C, a meta-analysis of ten randomized controlled trials including nearly 500 participants showed a significant improvement in lung function in individuals that supplemented 400 milligrams of oral vitamin C per day [ 15 ]. Additional benefits with fewer pulmonary exacerbations have been described in patients with COPD that received two grams of daily oral vitamin C supplementation [ 113 ]. In general, vitamin C poses few health risks and has been deemed safe to consume with no lasting health consequences, even in circumstances where extremely high concentrations are ingested in a single dose [ 124 ].…”

Section: Vitamins a B C And Ementioning

confidence: 99%

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The Role of Nutrition in the Development and Management of Chronic Obstructive Pulmonary Disease

Heefner,

Simovic,

Mize

et al. 2024

Nutrients

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Chronic obstructive pulmonary disease (COPD) is a prevalent lung condition associated with significant morbidity and mortality. The management of COPD classically involves pulmonary rehabilitation, bronchodilators, and corticosteroids. An aspect of COPD management that is currently lacking in the literature is nutritional management, despite the prevalence of inadequate nutritional status in patients with COPD. In addition, certain nutritional imbalances have been reported to increase the risk of COPD development. This review summarizes the current literature on the role diet and nutrients may play in the risk and management of COPD development.

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Section: Vitamins a B C And Ementioning

confidence: 90%

Section: Vitamins a B C And Ementioning

confidence: 99%

The Role of Nutrition in the Development and Management of Chronic Obstructive Pulmonary Disease

Heefner,

Simovic,

Mize

et al. 2024

Nutrients

View full text Add to dashboard Cite

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The Effectiveness of Supplementation with Key Vitamins, Minerals, Antioxidants and Specific Nutritional Supplements in COPD—A Review

et al. 2023

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Currently, an increasing amount of evidence supports the notion that vitamins C, D and E, carotenoids, and omega-3 fatty acids may protect against the progression of chronic respiratory diseases. Although chronic obstructive pulmonary disease (COPD) primarily affects the lung, it is often accompanied by extrapulmonary manifestations such as weight loss and malnutrition, skeletal muscle dysfunction, and an excess of harmful oxidants, which can lead to a decline in quality of life and possible death. Recently, the role of various vitamins, minerals, and antioxidants in mitigating the effects of environmental pollution and smoking has received significant attention. Therefore, this review evaluates the most relevant and up-to-date evidence on this topic. We conducted a literature review between 15 May 2018 and 15 May 2023, using the electronic database PubMed. Our search keywords included COPD, chronic obstructive pulmonary disease, FEV1, supplementation: vitamin A, vitamin D, vitamin E, vitamin C, vitamin B, omega-3, minerals, antioxidants, specific nutrient supplementations, clinical trials, and randomized controlled trials (RCTs). We focused on studies that measured the serum levels of vitamins, as these are a more objective measure than patient self-reports. Our findings suggest that the role of appropriate dietary supplements needs to be reconsidered for individuals who are predisposed to or at risk of these conditions.

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Long-term use of Vitamin-C in chronic obstructive pulmonary disease

Cited by 2 publications

References 4 publications

The Role of Nutrition in the Development and Management of Chronic Obstructive Pulmonary Disease

The Role of Nutrition in the Development and Management of Chronic Obstructive Pulmonary Disease

The Effectiveness of Supplementation with Key Vitamins, Minerals, Antioxidants and Specific Nutritional Supplements in COPD—A Review

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