Long-term visual outcomes of penetrating keratoplasty for Peters anomaly

Abstract

The results of delayed PKP in Peters anomaly were not inferior compared to the results of PKP performed at an earlier period in previous studies. If other congenital ophthalmic anomalies were present or graft rejection occurred within 1 month after PKP, the chance of graft failure was significantly increased.

Optimising keratoplasty for Peters' anomaly in infants using spectral-domain optical coherence tomography

“…Previous studies have shown that about 50% of patients with anterior segment dysgenesis develop glaucoma 38. The incidence of cases accompanied by glaucoma in our study was similar to that in previous reports 3 4 8. Assessing SD-OCT parameters may be useful for exploring the reason for high intraocular pressure in patients and for categorising Peters' anomaly, although independent studies with a larger sample size are warranted to verify our findings.…”

“…Corneal vascularisation was observed in 18 eyes (40.9%). A graft host disparity of 0.5–1.0 mm was used for the keratoplasty as described before 4. In the current study, the mean host cornea bed and the mean donor cornea button diameters were 6.3±0.2 and 7.1±0.2 mm, respectively.…”

“…Ophthalmic evaluations before corneal transplantation included slit-lamp and SD-OCT examinations of the anterior segment, intraocular pressure measurement (Tono-Pen XL; Reichert Technologies, DePew, New York, USA), and a fundus examination with an indirect ophthalmoscope. The technique used for penetrating keratoplasty was the same as previously described by Chang and colleagues 4. Lensectomy combined with anterior vitrectomy was performed if cataracts or lenticulo-corneal adhesions were identified 25.…”

“…Clinical features of patients with Peters' anomaly have been widely reported 5–8. Because, corneal opacity can impair visual development in infants, corneal transplantation is recommended as early as possible 4 9–12. The surgery-related ophthalmic examination of infants is often challenging because of the difficult cooperation in infants.…”

Type II Peter’s anomaly with histopathological proof: a case report

“…Whether the IOL implantation will be performed depends on the age and ocular condition of patient [18, 19]. By measuring the size, location, and density of the opacity, penetrating keratoplasty may be considered, especially when the opacity obstructs the optical pathway [24]. Meanwhile, postoperative optical correction and occlusion therapy are necessary for better visual recovery.…”