Long-Term Visual Outcomes of Secondary Intraocular Lens Implantation in Children with Congenital Cataracts

Xiao, Rong; Ji, Yinghong; You, Fang; Jiang, Yongxiang; Lü, Yi

doi:10.1371/journal.pone.0134864

Cited by 25 publications

(31 citation statements)

References 26 publications

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“…BCVA was evaluated using the Teller Acuity Card Test (Vistech, Dayton, Ohio, USA) in preverbal children or the Snellen chart or “E” charts in older children. The results were converted to the logarithm of the minimum angle of resolution (LogMAR) for statistical analysis 3 38 . The BCVA was recorded at the last follow-up visit after surgery.…”

Section: Methodsmentioning

confidence: 99%

“…Although visual acuity can be surgically restored in children with CC, there is great variability in visual outcomes following cataract surgery; some children achieve good postoperative visual acuity, whereas others obtain poor visual outcomes. It has been reported that 5.3% (4/76) of eyes achieve a best-corrected visual acuity (BCVA) of greater than 1.0 and that 7.9% (6/76) of eyes achieve a BCVA of less than 0.1 after bilateral cataract extraction and secondary intraocular lens (IOL) implantation 3 .…”

mentioning

confidence: 99%

“…Over the past decade, various studies have assessed visual outcome following bilateral CC, but the majority of these studies have been small sample sized series 4 5 6 . Although it has been reported that numerous factors may affect the final visual outcome after CC surgery 3 7 8 9 10 11 12 13 14 15 16 , the crucial factors remain uncertain. A better understanding of the effects of the related factors on visual outcome, considering both direction and amplitude in children with CC, is the fundamental step toward vision restoration.…”

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confidence: 99%

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Visual Outcome and Related Factors in Bilateral Total Congenital Cataract Patients: A Prospective Cohort Study

Zhang

Lin

et al. 2016

Sci Rep

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This study is to evaluate the visual outcome and identify its crucial related factors in children undergoing cataract surgery for bilateral total congenital cataract (CC). This prospective study included consecutive bilateral total cataract patients undergoing primary surgery at Zhongshan Ophthalmic Center (ZOC), Guangzhou, China from Jan 2010 to May 2014. Visual outcome was estimated by best-corrected visual acuity (BCVA) at last follow-up. Potential related factors, including gender, age at last follow-up, age at primary surgery, surgical procedure, postoperative complications (PCs), frequency of follow-up and changes in spectacles were evaluated. Eighty-eight children (176 eyes) were included in the cohort. The mean post-operative BCVA (logMAR) was 1.07 ± 0.53 at the mean follow-up duration 31.07 ± 19.36 months. Multivariable generalized estimating equations (GEEs) showed BCVA was significantly associated with PCs, age at last follow-up and age at primary surgery. Partial correlation analysis indicated age at primary surgery was positively correlated with BCVA controlling for the other factors, both for the whole age range (R = 0.415, P < 0.001) and age >6 months (R = 0.867, P < 0.001). Better visual acuity was related to early primary surgery and low PC occurrence in children with bilateral total CC. Timely surgical intervention and strict control of PCs would be potential steps to achieving better visual outcome.

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Section: Methodsmentioning

confidence: 99%

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confidence: 99%

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confidence: 99%

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Visual Outcome and Related Factors in Bilateral Total Congenital Cataract Patients: A Prospective Cohort Study

Zhang

Lin

et al. 2016

Sci Rep

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“… 11 Parental cooperation was defined according to their compliance for at least 50% of recommended patching hours by asking them at follow-up visits. 12 Partial compliance was considered if parents did not have compliance more than 50% of a day in all periodic follow-ups.…”

Section: Methodsmentioning

confidence: 99%

Long-term visual outcome of congenital cataract at a Tertiary Referral Center from 2004 to 2014

Rajavi

Mokhtari

Sabbaghi

et al. 2015

Journal of Current Ophthalmology

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PurposeTo assess the long-term visual acuity (VA) outcome after congenital cataract surgery at Imam Hossein Medical Center (Tertiary Referral Center) (2004–2014).MethodsIn this descriptive study, records of 120 patients with a history of congenital cataract surgery were studied. Those with traumatic, metabolic cataract, aged <5 years at the last visit who were not able to respond VA testing accurately and follow-up < 6 months were excluded. Cases with incomplete files were recalled and reexamined. Finally, the records of 42 patients (71 eyes) were included.ResultsIn this study, 20 males and 22 females with a mean age of 11.80 ± 6 years at their last visit were studied. Bilateral and unilateral cataract was seen in 69% and 31% of cases, respectively. Posterior and anterior subcapsular opacity was the most common (53.70%) and rarest (1.90%) type of congenital cataract, respectively. The mean age at the time of operation and surgical interval was 65 ± 66.6 (range: 1–200) and 12.9 ± 23.5 (range: 0–96) months, respectively. The most common method of refractive error correction was pseudophakia plus glasses (56.3%) with the mean best corrected visual acuity (BCVA) of 0.29 ± 0.28 LogMAR., The mean BCVA was 0.7 ± 0.53 LogMAR for aphakic patients correcting by glasses. In our study, amblyopia (56%), glaucoma (23.90%), and posterior capsular opacity (16.40%) were observed during their follow-ups on an average of 76 ± 65 months (median: 60, range: 6–240). Unilateral cataract, aphakia, nystagmus, female gender, and strabismus were risk factors of VA loss.ConclusionBased on our results, 56% of cases showed amblyopia. It could be due to late operation (especially in unilateral cases), longer surgical interval between two eyes, and no compliance of amblyopia therapy. Early detection through screening may reduce the rate of amblyopia. Refractive errors, visual acuity, amblyopia, glaucoma, posterior capsular opacity, and compliance of amblyopia therapy should be checked regularly at follow-up visits.

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“…Konjenital kataraktların görülme sıklığı 10000 doğumda 1,2-6 arasında değişmektedir. Okul öncesi çocuklarda körlük nedenlerinin %10'unu oluştururken, yaklaşık % 34'ü de ailesel özellik taşımaktadır (1,(4)(5)(6)(7)(8).…”

Section: Discussionunclassified

Three Cases of Bilateral Congenital Spear Cataract Involvement in Three Members of the Same Family

Unsal¹,

Eltutar²,

Kizilay³

et al. 2016

Istanbul Med J

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GirişKonjenital katarakt doğumda var olan lens opasiteleridir ve dünyada çocuklarda önlenebilir kör-lük nedenlerinden en sık görülenidir (1, 2). Dolayısıyla zamanında teşhis edilip tedavisinin dü-zenlenmesi önemlidir. Biz de literatürde çok sık görülmeyen otozomal dominant geçişli mızrak katarakt tanılı hastaların çocuklarının da göz muayenelerinin ayrıntılı yapılıp, katarakt dışında ambliyopi ve/veya şaşılık açısından da değerlendirilmesi gerektiğini düşünerek anneanne, anne ve kızından oluşan bir ailedeki bilateral mızrak katarakt olgularını sunmak istedik. Olgu SunumuOlgu 1: 79 yaşında bayan hasta. Sağ ve sol görmesi gözlük ile 0,3 logMAR unit olarak saptandı. Ön segment muayenesinde bilateral, uçları sivri, mızrak şekilli, lens nükleusundan lens korteksine doğru uzanmış kristal gibi parlayan lens opasiteleri saptandı (Resim 1). Fundus doğaldı. Göz içi basınçları normal seviyede idi. Çocukluktan beri aynı düzeyde görmesi olduğunu belirtti. Katarakt operasyonu düşünülmedi. Hasta takibe alındı. The aim of this study was to present bilateral spear cataracts in a grandmother, mother, and daughter of the same family. A 79-year old female patient. The best corrected visual acuity was 0.3 logMAR units in the right and left eyes. An anterior segment examination revealed a bilateral spear cataract. The posterior segment was normal. Intraocular pressure was within the normal range. As the patient said that she has had the same level of vision acuity since childhood, cataract surgery was not considered. Follow-up was recommended. A 45-year-old female presented to our clinic for a routine eye examination. The best corrected visual acuity was 0.4 logMAR units in the right eyes and 0.1 logMAR units in the left eye. During the slit lamp examination, bilateral congenital spear cataracts were detected. Bilateral intraocular pressure levels were within the normal range. An 8-year-old female presented to our clinic for a routine eye examination. Evaluation of crystalline lenses revealed bilateral congenital spear cataracts. After cycloplegic examination was performed, refractive errors in the right and left eyes were detected. These were (+1.00 α 90°) and +1.00 (-2.50 α 5°), respectively. The best corrected visual acuity was found to be 0.05 logMAR units in the right eye and 0.2 logMAR units in the left eye. Against the possibility of amblyopia of the left eye, patching of the right eye and follow-up were recommended. Opacities involve the outer layer of the embryonic nucleus and inner layer of the infantile nucleus. It is thought that they are crystals containing tyrosine and calcium sulfate. They disturb the vision and are prone to carry an autosomal dominant trait. Our cases comprise a grandmother, mother, and daughter of the same family. Due to this type of cataract, a high rate of lenticular astigmatism comorbidity is commonly seen. Keywords: Congenital cataract, spear cataract, genetic switchAynı aileden üç olguda konjenital bilateral mızrak katarakt olgusunu sunmayı amaçladık. 79 yaşında bayan hasta. Sağ ve sol görmesi g...

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Long-Term Visual Outcomes of Secondary Intraocular Lens Implantation in Children with Congenital Cataracts

Cited by 25 publications

References 26 publications

Visual Outcome and Related Factors in Bilateral Total Congenital Cataract Patients: A Prospective Cohort Study

Visual Outcome and Related Factors in Bilateral Total Congenital Cataract Patients: A Prospective Cohort Study

Long-term visual outcome of congenital cataract at a Tertiary Referral Center from 2004 to 2014

Three Cases of Bilateral Congenital Spear Cataract Involvement in Three Members of the Same Family

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