Longitudinal assessment of lung function decline in the occupational setting

Redlich, Carrie A.; Tarlo, Susan M.

doi:10.1097/aci.0000000000000153

Cited by 8 publications

(2 citation statements)

References 36 publications

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“…In a recent review lung function tests have shown to be able to identify novel occupational respiratory diseases such as flavoring-related lung disease [24].…”

Section: Discussionmentioning

confidence: 99%

Pulmonary functionality among workers of a Central Italy waste-to-energy plant: a retrospective study

Coppeta

Pietroiusti

Policardo

et al. 2019

J Occup Med Toxicol

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Background We are observing a growing trend towards the use of waste incineration in waste-to-energy (WTE) plants in Italy. Various authors started to investigate their potential health effects, but without univocal outcomes. The aim of this study is to assess whether or not main pulmonary function indexes could be decreased in a group of workers employed in a municipal solid WTE plant located in Central Italy, and if there’s a correlation between the levels of exposure to airborne pollutants and alterations in the pulmonary apparatus. Methods The study was conducted with a retrospective cohort approach. We reviewed data from clinical records of 58 waste-to-energy plant workers undergoing annual health surveillance in the period 2010–2015. We considered the exposure to airborne dust and the main parameters of respiratory function (FVC, FEV1, Tiffeneau Index and FEF 25–75%) at time zero and after a period of 5 years. We divided our study population into two groups: low (< 1 mg/m3) and high (> 1 mg/m3) exposure. We estimated odds ratios (OR) with 95% confidence interval (95% CI) adjusted for potential confounders. Results We observed a decrease in lung function parameters both in high and in low exposure group after a five-years exposure period. FEV1, FEV1/VC ratio and FEF 25–75% were worst in more exposed group, even if this difference resulted not significant at Wilcoxon test. Conclusions Active employee in WTE plants is associated to a non-significant worsening in the main parameters of lung function after 5 years exposure. Clinical significant of these variations need to be assessed.

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“…In a recent review lung function tests have shown to be able to identify novel occupational respiratory diseases such as flavoring-related lung disease [24].…”

Section: Discussionmentioning

confidence: 99%

Pulmonary functionality among workers of a Central Italy waste-to-energy plant: a retrospective study

Coppeta

Pietroiusti

Policardo

et al. 2019

J Occup Med Toxicol

View full text Add to dashboard Cite

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“…Most workplace-based studies examining occupational exposures and lung function have been cross-sectional in design and focused on specific exposures or employment. Coal miners, gold miners, farmers, bakers, timber, cotton textile manufacturing, and asbestos and construction workers have all been assessed, [43][44][45] and large general population cohorts have confirmed the occupational contribution to lung function decline. 45 Data from longitudinal studies do exist but are difficult to merge given the differences between exposures.…”

Section: The Issue Of Longitudinal Change Assessed By Spirometry In O...mentioning

confidence: 95%

Physiology and Biomarkers for Surveillance of Occupational Lung Disease

Yates

2023

Semin Respir Crit Care Med

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Respiratory surveillance is the process whereby a group of exposed workers are regularly tested (or screened) for those lung diseases which occur as a result of a specific work exposure. Surveillance is performed by assessing various measures of biological or pathological processes (or biomarkers) for change over time. These traditionally include questionnaires, lung physiological assessments (especially spirometry), and imaging. Early detection of pathological processes or disease can enable removal of a worker from a potentially harmful exposure at an early stage. In this article, we summarize the physiological biomarkers currently used for respiratory surveillance, while commenting on differences in interpretative strategies between different professional groups. We also briefly review the many new techniques which are currently being assessed for respiratory surveillance in prospective research studies and which are likely to significantly broaden and enhance this field in the near future.

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