2024
DOI: 10.1002/alz.14439
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Longitudinal cognitive performance of participants with sporadic early onset Alzheimer's disease from LEADS

Dustin B. Hammers,
Ani Eloyan,
Alexander Taurone
et al.

Abstract: INTRODUCTIONEarly‐onset Alzheimer's disease (EOAD) manifests prior to the age of 65, and affects 4%–8% of patients with Alzheimer's disease (AD). The current analyses sought to examine longitudinal cognitive trajectories of participants with early‐onset dementia.METHODSData from 307 cognitively normal (CN) volunteer participants and those with amyloid‐positive EOAD or amyloid‐negative cognitive impairment (EOnonAD) were compared. Cognitive trajectories across a comprehensive cognitive battery spanning 42 month… Show more

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