2024
DOI: 10.1101/2024.04.08.24305500
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Longitudinal course of inflammatory-cognitive subgroups across first treatment severe mental illness and healthy controls

Linn Sofie Sæther,
Thor Ueland,
Beathe Haatveit
et al.

Abstract: Background While inflammation is associated with cognitive impairment in severe mental illnesses (SMI), there is substantial heterogeneity and evidence of transdiagnostic subgroups across schizophrenia (SZ) and bipolar (BD) spectrum disorders. There is however, limited knowledge about the longitudinal course of this relationship. Methods Systemic inflammation (C-Reactive Protein, CRP) and cognition (nine cognitive domains) was measured from baseline to 1 year follow-up in first treatment SZ and BD (n=221), and… Show more

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