Longitudinal Left Ventricular Strain in Hypertrophic Cardiomyopathy: Correlation with Nonsustained Ventricular Tachycardia

Abstract

Lower end-systolic peak longitudinal strain obtained by 2D speckle tracking was a predictor of NSVT in HCM patients. This parameter could become a useful tool in stratifying SCD risk in this population.

Four‐Dimensional Speckle Tracking Echocardiography in Patients with Hypertrophic Cardiomyopathy

“…Normal strain is the deformation components along the main axes of a coordinate system. Reduced longitudinal function, which is mainly due to subendocardial fibers, may be explained by the fact that subendocardium is more vulnerable to perfusion abnormalities and arrhythmia 22,23 and more affected by interstitial fibrosis than other segments. Radial strain has been reported to be normal or reduced in HCM, 12 whereas circumferential strain has been found to be either increased, normal, or reduced.…”

Comparison of Resting and Exercise Echocardiographic Parameters as Indicators of Outcomes in Hypertrophic Cardiomyopathy

“…26 Two studies have shown regional longitudinal strain < 10% to be an independent predictor of relatively soft cardiac events, such as nonsustained ventricular tachycardia. 27,28 Concerning more serious cardiac events, Saito et al 15 showed in 48 patients with HCM that GLS was significantly lower in patients with myocardial fibrosis on cardiac magnetic resonance imaging than in those without. Multivariate analysis revealed GLS to be an independent predictor of the percentage of late gadolinium enhancement.…”

Non-invasive imaging and monitoring cardiotoxicity of cancer therapeutic drugs

“…More novel techniques such as strain imaging with 2D echocardiography has been used to detect subclinical LV dysfunction and has demonstrated predictive value in disease states such as cardiac amyloidosis, 65 hypertrophic cardiomyopathy, 66 as well as determining viability prior to revascularization in patients with CAD. 67 In a cohort of asymptomatic survivors of pediatric malignancy, strain and strain rate were decreased when compared with normal controls.…”